Because t^2 = F when two groups are being compared, negative F-values correspond to imaginary t-values. Imaginary t-values mean your effect is unbelievably strong.

The AI can’t color inside two lines indicating the boundary of cortical layer and trying to gaslight me into believing F statistics can be negative

Vinny Costa@vincentcostaphd.bsky.social · last wk.

The AI is hallucinating the accuracy of its brain region label annotations and is trying to gaslight me into believing there are 4 lights, so yes, absolutely we’re 3-4 years away from all neuroscientists filing for unemployment.

The apical dendrite looks great, and does wonders in a slice. What does it do in the living cortex? It depends on the cell. A causal spatial role for apical dendrites in the cortex www.biorxiv.org/content/10.6... by @anyiliu.bsky.social with @kenneth-harris.bsky.social and @fedrossi.bsky.social

📣New paper! How does the sleeping brain help us to integrate new experiences while managing memories from the past? For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n www.nature.com/articles/s41... 🧪🧠📈👩‍🔬#OpenAccess

Experience reorganizes content-specific memory traces in macaques - Nature Neuroscience

In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep and can sometim...

nature.com

Why do people stop pursuing goals they care about❓ Motivational deficits are among the most disabling symptoms, yet current treatments often have only modest effects. In @lillyt.bsky.social new paper, she asks if we're missing an important piece of the puzzle 🧠 #neuroscience #cogpsyc #psychscisky

Arousal shapes motivation: an integrative framework for understanding motivational deficits - Translational Psychiatry

Translational Psychiatry - Arousal shapes motivation: an integrative framework for understanding motivational deficits

nature.com

🚨 Want to start your lab in Marseille on a broad neuronal/brain development theme? There's an exciting tenure track opportunity at @inp-marseille.bsky.social and others Marseille institutes! Check more details here: neuro-marseille.org/en/blog/juni... or contact me if you have any question

Elnahal cited the thousands of scientists who contacted him from around the globe as indicating that OHSU has something special in terms or resources. You did. It was a primate center. With the new plan & colony reduction, you lose it. You reap what you sow. In this case, mediocrity & uncertainty

The Transmitter @thetransmitter.bsky.social · last wk.

The board of directors at Oregon Health & Science University has voted unanimously to develop a plan to scale down the university’s primate research center and pivot its focus to new approach methodologies. #neuroskyence By @callimcflurry.bsky.social www.thetransmitter.org/nonhuman-pri...

Good article and good to hear prominent NHP voices like Peter Strick speaking up about this unforced error. President Elenahal is delusional if he believes his statement that the scientific community is going to continue collaborations with ONPRC. Oregon and OHSU are now a scientific backwater.

The Transmitter @thetransmitter.bsky.social · last wk.

The board of directors at Oregon Health & Science University has voted unanimously to develop a plan to scale down the university’s primate research center and pivot its focus to new approach methodologies. #neuroskyence By @callimcflurry.bsky.social www.thetransmitter.org/nonhuman-pri...

I did not think I would be running a snark filled RCR course in public today.

Board passed the resolution.

Vinny Costa@vincentcostaphd.bsky.social · 2w ago

The President of OHSU Shereef Elnahal and the OHSU Board of Directors will be voting to effectively gut research and shutdown the Oregon National Primate Research Center on 7/27/2027. Public comments can be submitted here until 3PM EST today. savescienceoregon.org/contact

Lacks did sign a consent form. The problem was that it wasn't informed consent (i.e.there was no attempt make sure she read & understood the form) and the form did not explain types of research planned. One can argue for very broad consents, but the Q about what uses need to be explicit is the same.

Seriously? I mean I guess when you hyperscale the compute the whole world looks like a flesh carnival to be devoured for longevity optimization. It needs to be super specific to protect. People have no idea what the tissue could be used for in the future and it’s not for you to decide for them.

Someone needs to retake their human ethics refresher course module. Consent forms are specific for a reason.

Blake Richards@tyrellturing.bsky.social · last wk.

Okay, at the risk of getting yelled at here, my reaction is, who cares? Like, whoever this happened to consented to having their cells used for scientific research. Why does it matter if they end up being used for organoids to study neural computation? The article doesn't give a good answer, IMO.

The AI is hallucinating the accuracy of its brain region label annotations and is trying to gaslight me into believing there are 4 lights, so yes, absolutely we’re 3-4 years away from all neuroscientists filing for unemployment.

Zapping without mapping = no bueno ! Cool paper www.science.org/doi/full/10....

Focused ultrasound blood-brain barrier opening reveals a paradoxical remote metabolic response in the primate brain

Using focused ultrasound to open the BBB paradoxically induces metabolic stress in distant brain regions.

science.org

Yale is hiring in developmental psychology (open rank )! We're especially interested in complementing and broadening our area, including via somewhat less traditionally central such as cross-cultural and comparative approaches. Feel free to reach out with questions!

The President of OHSU Shereef Elnahal and the OHSU Board of Directors will be voting to effectively gut research and shutdown the Oregon National Primate Research Center on 7/27/2027. Public comments can be submitted here until 3PM EST today. savescienceoregon.org/contact

Our new study ⬇️inspired by the question: does psilocybin influence meta-learning and cortical processing of unexpected uncertainty? Why is this important? Meta-learning may be critical for therapeutic effects of psychedelics and how the trip creates a window that facilitates clinical intervention

Just low key checking on feasibility of getting from Barcelona to Paris and back since #RLDM2027 and #AmygdalaGRC2027 are both in Europe at the same time.

Visual illustration of respect to our teams doing this work... absolutely perfect sectioning when you've got one shot onto specialized slides with precious tissue is a LOT of pressure. Shout out on this one to Staff Scientist Sara Maurer and RA Felix Siewe for some exciting upcoming data collection!

Keri Martinowich@martinowk.bsky.social · 2mo ago

Thanks @vincentcostaphd.bsky.social - truly appreciate the respect for what our teams @lieberinstitute.bsky.social are doing on the spatial data generation front - they're amazing. I can't take the credit, so I'm going to use this as an excuse to give a shout out to the people running that engine.

This is awesome and one reason why I am so excited about the RMA technology @jerzyszablowski.bsky.social has developed with his lab. Theranos was a great idea ruined by a fraud. The blood supply can be repurposed as a diagnostic tool in so many cool ways. www.sciencedirect.com/science/arti...

Watchdog Progressive@watchdogprg.bsky.social · 2w ago

Wow! >>> UCLA researchers develop low-cost blood test to detect multiple cancers and other diseases from a single sample. newsroom.ucla.edu/releases/ucl...

It's been a year in the making but I am happy to announce our UNC Neurophysiology core facility is online. What do we do? Patch clamp (from almost anything), calcium imaging, ABR, EEG, and more! Ready to help labs, research institutes, and companies anywhere! Details: www.med.unc.edu/neurophyscore/

is crystal pepsi made by the crystalline entity

The mammalian cortex is a polycule in Bushwick.

Just listening to Nelly Furtado’s song Promiscuous while reading that Nature paper about how there is no neuronal specialization in the mouse brain outside visual cortex, with this paper from @rudebecklab.bsky.social & @zachzeisler1.bsky.social open in the background www.cell.com/current-biol...

Comparative basolateral amygdala connectomics reveals dissociable single-neuron projection patterns to frontal cortex in macaques and mice

Zeisler et al. compare the projection patterns of single BLA neurons from mice and macaques using MAPseq. They reveal that BLA projections, particularly to frontal cortex, exhibit a number of differen...

cell.com

🚨Postdoc position available in computational/theoretical neuroscience at NIMH! The intramural NIH research community is great (amazing collaborators, no worrying about grants, lots of opportunities for professional development). Please repost! www.training.nih.gov/jobs/pd-0931...

A periodic reminder - don't use an LLM to write your emails to prospective PhD supervisors, lest they be people like me that will just delete your message without replying.

Just submitted my comments on the OMB proposed rule. Gets yours in before tomorrow afternoon.

Jenna Norton@jenna-m-norton.bsky.social · 4w ago

Keep those comments on the OMB proposed rule coming! www.insidehighered.com/news/governm...

Our labs first paper! Some 😳 surprising effects. Turns out everything comes back to context 🤓

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 4w ago

Ventral tegmental area acetylcholine generates appetitive and aversive incentive motivation https://www.biorxiv.org/content/10.64898/2026.07.09.737546v1

Vehicle glove compartments used to be filled with paper road atlases for every state you would visit. The really nice ones were printed on glossy, thick paper stock for when you invariably spilt your coffee on them. Also, gas cost < $1 a gallon.

Alex Navarro@alexnavarro.bsky.social · 4w ago

people talk a lot about pre/post-internet microgenerations but let me hear from all the others in my microgeneration, the “printing maps off Mapquest” microgeneration.