Kip Ludwig

@wildpiguk.bsky.social

Former NIH Program Director for Neuroengineering. Current Co-Director of Wisconsin Institute for Translational Neuroengineering (WITNe). Opinions are official positions of the U.S Government and Lyle Lovett.

I’ve just come to the shocking self-realization that both my science and comedy writing are essentially the same thing. I bluntly say a bunch of blatantly obvious things that for whatever reason people have sub consciously avoided thinking about. Ironically, I never caught that before myself.

Roughly half of intracortical microelectrodes lose recording capability within a year of implantation. The B.I.O.N.I.C. Lab at Pitt is hiring a postdoc to attack the mechanism on two parallel grant-funded threads. 🧵 (1/7)

I keep seeing how #Elon #Musk will be the world's first trillionaire with the SpaceX IPO. If you take the value of all wealth and assets, the whole world is estimated at ~450 trillion dollars. There are ~8.3 billion people. For 1 person to have 1/450 of ALL OF IT is neither sustainable nor ethical.

They published it at 412 pages on a Friday afternoon, the slot networks call "take out the trash." OMB-2026-0034 lets political appointees override peer review, ban publication funding, and terminate grants without cause. They gave you 45 days. They're counting on you not reading it.

OMB just published 412 pages in the Federal Register (Docket OMB-2026-0034) giving political appointees authority to terminate any NIH grant, override peer review scores, and block you from publishing with federal funds. Comment period closes ~July 13. Thread 🧵

Bild

⚠️ Late Friday afternoon, May 15, while reporters were leaving for the weekend, HHS quietly cut more NIH staff and began moving senior career employees into "at-will" status under the renamed Schedule F. No press release. No published list. A "first tranche," with more to come. 🧵

Bild

🧠 Half of animals receiving the most commonly used clinical brain stimulation frequency developed seizure-like activity. But only after six weeks. Long past the point where most safety studies stop looking. New paper, final version out in Biomaterials. 🧵

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🗑️ Every neuron in your brain has a waste management system. When it fails near a chronically implanted electrode, the cell does not die immediately. It accumulates damage quietly, for weeks, before it shows up in your recordings. 🧵

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🚨 Congress held NIH and NSF budgets roughly flat. Scientists celebrated. Here is what actually happened. NIH awarded 4,641 fewer grants in FY2025 than the 4-year avg. New awards dropped 14%. Over $1.3B never reached investigators. NSF awards fell 22%. The money was there.

This is only true for people who understand neither science nor economics. The NIH budget for this year is FIFTY times larger than OpenAI’s $1B pledge. The foundation of US science & innovation is public funding. The private sector cannot replace it. US science is being killed

roon @tszzl
the private sector has been remaking its own versions of NIH, ARPA etc as these public science institutions have seen structural decline and defunding and it will be supercharged by the funding NPV of machine intelligence and its firepower at allocation decisions