I am hereby exclusively calling #LLM based #AI word guessing programs. #dontbelievethehype
Kip Ludwig
@wildpiguk.bsky.social
Former NIH Program Director for Neuroengineering. Current Co-Director of Wisconsin Institute for Translational Neuroengineering (WITNe). Opinions are official positions of the U.S Government and Lyle Lovett.
I’m one of 155 physicians & scientists who signed this open letter calling on elected officials to end the vilification & harassment of scientists like Peter Hotez & Anthony Fauci We urge them to “stop these witch-hunts” www.medpagetoday.com/washington-w...
Stop 'Harassment' of Fauci, Scientists Urge Politicians
Open letter signed by 155 physicians, scientists ahead of Congressional testimony
medpagetoday.com
Whew, the editors of @science.org are getting real.
The Assault On Science Funding Continues
science.org
I co-sign this great summary from @dereklowe.bsky.social . The goal is to destroy academic science, and these are the reasons. And all the “gold standard” and “needs reform” and “not high risk” stuff is transparent bullshit to hide the ball on what they are doing.
Thoughts on the various Trump administration proposals to revamp US science funding - and what they all have in common:
100% on target—this is the way to think about the Trump science plan.
Once you understand that this is a model of science written by non-scientists who hate universities but love venture capital and redirecting money to political allies, everything makes a lot more sense. www.nytimes.com/2026/07/22/u...
Long-term safety and efficacy of intracortical microstimulation in humans www.science.org/doi/10.1126/... "electrodes maintained sufficient activity for 2 to 10 years; #ICMS #BCI #NeuroTech
Long-term safety and efficacy of intracortical microstimulation in humans
Intracortical microstimulation in humans is safe and efficacious for up to 10 years.
science.org
“if I was trying to ruin American leadership in scientific research this is pretty much the kind of rule I would write.” Worth reading the whole thing from @dandrezner.bsky.social . I have two things to add to what he says: 1/
Good morning. Nothing to see here, just the possible end of American scientific research as we know it. open.substack.com/pub/danieldr...
I’ve just come to the shocking self-realization that both my science and comedy writing are essentially the same thing. I bluntly say a bunch of blatantly obvious things that for whatever reason people have sub consciously avoided thinking about. Ironically, I never caught that before myself.
Regardless of party, can we all agree not to support very bad people? The #whataboutism has got to stop. #goodpeopleoverparty
www.nytimes.com/2026/07/06/u... an ominous trend: graduate admissions are down 15 percent from last year, on top of an 11 percent decrease from the previous year we are destroying our seed corn
Research Universities Are Admitting Fewer Ph.D.s, a Bad Sign for Science
nytimes.com
“Our study reveals prevalent brittleness in the presence of simple adversarial transformations: leading systems can guess the correct answer even with key inputs removed yet may get confused by the slightest prompt alterations…” #AI www.nature.com/articles/s41...
Evaluating the robustness and readiness of large frontier models in health AI applications - Nature Medicine
Adversarial evaluation of leading AI models uncovers gaps between benchmark success and robustness, highlighting limitations in current health AI benchmarks and their ability to capture clinically rel...
nature.com
Roughly half of intracortical microelectrodes lose recording capability within a year of implantation. The B.I.O.N.I.C. Lab at Pitt is hiring a postdoc to attack the mechanism on two parallel grant-funded threads. 🧵 (1/7)
A @nejm.org editorial today on the Office of White House Management and Budget (OMB) regarding their new funding proposal and politicization of science www.nejm.org/doi/full/10....
The good news is knowing IS half the battle. The bad news is the other half usually involves killing people. #GIJoe kind of glossed over that part growing up.
They published it at 412 pages on a Friday afternoon, the slot networks call "take out the trash." OMB-2026-0034 lets political appointees override peer review, ban publication funding, and terminate grants without cause. They gave you 45 days. They're counting on you not reading it.
Neuropixels + Optogenetics = Neuropixels Opto Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors. Today in @natmethods.nature.com doi.org/10.1038/s415... Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
OMB just published 412 pages in the Federal Register (Docket OMB-2026-0034) giving political appointees authority to terminate any NIH grant, override peer review scores, and block you from publishing with federal funds. Comment period closes ~July 13. Thread 🧵
The White House today announced it plans to make major changes in how the U.S. government manages research funding. https://scim.ag/43HgW4s
White House seeks to tighten political oversight of grantmaking
Sweeping proposed rule, now open for comments, would also restrict foreign collaborations and remove federal funding for open-access fees
scim.ag
⚠️ Late Friday afternoon, May 15, while reporters were leaving for the weekend, HHS quietly cut more NIH staff and began moving senior career employees into "at-will" status under the renamed Schedule F. No press release. No published list. A "first tranche," with more to come. 🧵
This is the slow death of NIH by design. The architect is Russell Vought. He is the man who architected the RIFs & probationary terminations. He devised the multiyear funding and censorship schemes. If you don't like what you see, let's get him impeached: actionnetwork.org/forms/civil-...
Civil Servants Demand: Impeach Russell Vought
The Office of Management and Budget Director Russell Vought is the central architect driving the destruction of your government. Russell Vought created lawlessness in every part of the Trump administ...
actionnetwork.org
NEW: A serious staffing shortage — of the Trump admin's own making — is delaying the agency's ability to send billions to universities around the country, leaving labs reeling in the meantime. “I thought we were at rock bottom”, a senior NIH official said. “We are below rock bottom now.”
🧠 Half of animals receiving the most commonly used clinical brain stimulation frequency developed seizure-like activity. But only after six weeks. Long past the point where most safety studies stop looking. New paper, final version out in Biomaterials. 🧵
🗑️ Every neuron in your brain has a waste management system. When it fails near a chronically implanted electrode, the cell does not die immediately. It accumulates damage quietly, for weeks, before it shows up in your recordings. 🧵
I would like to announce that I will also be blocking the Straight of #Hormuz in addition to the #UnitedStates and #Iran. Our dog Lily will be joining me. So now it’s like really, really quadruple blocked. Especially if you are a squirrel. 🐿️
Slaughtering our golden goose: massive budget cuts for US science proposed again by Trump administration www.nature.com/articles/d41...
Massive budget cuts for US science proposed again by Trump administration
Budget proposal would also curb federal payments for scientific publishing.
nature.com
🚨 Congress held NIH and NSF budgets roughly flat. Scientists celebrated. Here is what actually happened. NIH awarded 4,641 fewer grants in FY2025 than the 4-year avg. New awards dropped 14%. Over $1.3B never reached investigators. NSF awards fell 22%. The money was there.
Our new paper. This one is important for anyone doing rodent #vagus nerve stimulation studies. iopscience.iop.org/article/10.1...
Prevalence of sympathetic fibers within the rat cervical vagus, and functional consequence on physiological effects mediated by vagus nerve stimulation (VNS)
Prevalence of sympathetic fibers within the rat cervical vagus, and functional consequence on physiological effects mediated by vagus nerve stimulation (VNS), Deshmukh, Ashlesha, Chen, Rex Chin-Hao, Chin, Justin, Knudsen, Bruce, Trevathan, James, Shoffstall, Andrew J, Ludwig, Kip
iopscience.iop.org
This is only true for people who understand neither science nor economics. The NIH budget for this year is FIFTY times larger than OpenAI’s $1B pledge. The foundation of US science & innovation is public funding. The private sector cannot replace it. US science is being killed