In this fascinating pre-print, authors tried to address clinical safety in LLMs by just ... asking nicely for it to apply a cost function penalizing under-triage. And it kind of works! But probably not well enough to rely upon. #medsky #MLsky www.evidencetriage.com/p/llms-can-b...

LLMs Can Be Commanded To Be Less Risky

In their own strange, probabilistic way.

evidencetriage.com

It is not "the PERC rule". That is all.

I Have Spoken The Mandalorian

ALT: I Have Spoken The Mandalorian

static.klipy.com

Can I interest you in an other Epic/ML/RRT fantasy of "hundreds of lives saved" by an alert? #medsky #MLsky www.evidencetriage.com/p/ai-guided-...

AI-Guided Rapid Response "Reduces Mortality"

But what do these interventions actually *do*?

evidencetriage.com

Remember these Texas Medical Center dashboards where they documented how many extra ICUs they opened?

Gabriel Bosslet@gbosslet.bsky.social · 3d ago

RFK Jr said these words today on national television "There were ICUs that were empty all over the country including in New York at the height (of the pandemic)" hahahahahahahahahahahahahahahahahahahahahahahahahahahahaha You are a fucking idiot hahahahahahahahahahahahahahahahaha <sobs silently>

Which peptide fixes your back Asking for a friend

New addition to the GRADE evidence framework: advertorial When a $180B company has to pay to publish a study from high-profile U.S.-based academic institutions as Open Access in The Lancet Regional Health Americas ... www.thelancet.com/journals/lan...

Whole-blood point of care biomarker testing following traumatic brain injury

In 2018, the U.S. Food and Drug Administration (FDA) first approved a blood test to aid clinical decision-making regarding CT imaging in patients following mild traumatic brain injury (TBI).1 This was...

thelancet.com

Let’s take two things that are almost free and make you pay money for them again.

MedPage Today@medpagetoday.com · 2w ago

The FDA approved a combination tablet of 325-mg acetaminophen and 110-mg naproxen sodium (Tylenol with Naproxen) for over-the-counter pain relief, the agency announced Friday. https://www.medpagetoday.com/neurology/painmanagement/122343

Another example of journals paying reviewers and reaping the benefits. It is a substantial investment on the part of the journal, however, and remains to be seen what sustainable models will ultimately emerge. #medsky www.evidencetriage.com/p/how-would-...

How Would You Like to Make £220?

(You don't have to review for free!)

evidencetriage.com

It's all well and good to develop a predictive or prescriptive model, but what's the actual health system impact? The real world wants to know. #medsky #mlsky www.evidencetriage.com/p/the-actual...

The Actual Consequences of Decision-Support

AI edition!

evidencetriage.com

Trust everyone.

­­　­　­　the­　­­　­　­ postes@rem.bsjky.team · 3w ago

Stop scrolling and post 2 characters who bring you happiness.

Alex Horne & Greg Davies' Handshake

ALT: Alex Horne & Greg Davies' Handshake

static.klipy.com

Seth Trueger@mdaware.org · 3w ago

Stop scrolling and post 2 characters who bring you happiness.

"LLMs are structurally indifferent to truth"

Anthony Moser@anthonymoser.com · 8mo ago

while i am not an academic i did see this coming and post about it on bluesky, which is why i am quoted in this article

“Murderbot, I see your performance reliability is dropping. I believe I may have something for that.” cc: @marthawells.com

Yep, the YEARS criteria are safe to use for exclusion of PE in patient with active cancer. #medsky www.evidencetriage.com/p/cancer-can...

Cancer Can't Stop YEARS

Keep cutting down those CTPAs with "Hydra".

evidencetriage.com

Can we use LLMs to screen patient safety "eTriggers" for missed opportunities for diagnosis? Yes (probably) – but bland one-shot prompting of general purpose models isn't going to do the trick. #medsky #MLsky www.evidencetriage.com/p/the-llm-as...

The LLM As QA Judge

A good low-risk administrative application, but still a ways to go.

evidencetriage.com

🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️ One milkshake to rule the boys, one milkshake to find them, one milkshake to bring the boys and in my yard to bind them 🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️🕯️

Every city's got an ominous megastructure.

Seth Trueger@mdaware.org · last mo.

Every city's got an ominous megastructure #bean

Conceptually, this is a fun project – and I agree continuous feedback is an important component of practicing medicine. That said, tossing additional anecdotes into your decision-making workflow will contribute to recency and availability biases. 🙃 #medsky www.michiganmedicine.org/health-lab/h...

How AI is helping emergency physicians learn from their patients

How the “Tell Me What Happens Next” initiative is being used by the Department of Emergency Medicine’s new Division of Clinical Informatics using artificial intelligence.

michiganmedicine.org

Stay With Your Group

Nearly 3 out of 4 clinicians are concerned about widespread clinical deskilling from overreliance on automation. Also, as patients increasingly bring AI-generated research to medical appointments, doctors and nurses find themselves spending more time acting as validators of outside data. #MedSky 3/5

All Whites have had their moments to celebrate, but an uphill climb left to go.

Fresh Blog: Is oseltamivir assassinating ICU patients? ☠️ The REMAP-CAP trial has concluded with >98% certainty that oseltamivir is killing patients. ☠️ This is an extraordinary claim that requires extraordinary evidence. #1/2... #EMIMCC

In case you missed it – this week's AI preview of our glorious clinician-replacement medical future. This week it's called "MIRA". #medsky #MLsky www.evidencetriage.com/p/mira-a-pre...

MIRA, A Preview Of The Endgame

Full-stack clinical replacement, closer every day.

evidencetriage.com

Hear me out … ketaperidol.

Anand Swaminathan@emswami.bsky.social · 2mo ago

Haloperidol is a Fantastic Multi-Tasker -Sedation of the agitated patient -Potent antiemetic particularly in gastroparesis (PMID 28320545) + CHS (PMID: 33160719) -Excellent in migraines (PMID 27510942) -Refractory sickle cell disease pain + chronic abdominal pain youtube.com/shorts/A5Ju5... #EMIMCC

Did you like getting your AI for free? It is the beginning of the "costs getting passed on to the user" reckoning .... #mlsky www.aguidetocloud.com/blog/microso...

Microsoft Copilot Cowork — New 2026 Pricing Guide

Microsoft Copilot Cowork pricing in plain English — the new two-part model (Copilot seat + Copilot Credits), what drives cost, and how to manage it.

aguidetocloud.com

When lipstick* on a pig turns it into a $10B unicorn. * the lipstick cost $20B. www.mcsweeneys.net/articles/ai-...

AI Economics for Dummies

“Xavier owns an apartment that he rents out at a loss of $1 billion/month. Seeing this success, he decides to make financial commitments to construct $850 bi...

mcsweeneys.net

Is it carbon monoxide

Cosmic Marvel@dailycosmicmarvel.bsky.social · 2mo ago

The villain of ‘SPIDER-MAN: BRAND NEW DAY’ is described as “a powerful villain no one can even see.” (via spidermanbrandnewday.movie/synopsis/)

An imminent question in the Southern Hemisphere, but not far off for the North – do we still keep giving oseltamivir to our critically unwell patients? How about the general hospital population? What about other antivirals – is "viral load" enough of a surrogate? www.remapcap.org/oseltamivir-...

How precarious is the valuation of OpenEvidence – when anyone can get better performance out of a general-purpose LLM, or even the much-maligned generative search result in Google? #medsky #mlsky www.evidencetriage.com/p/openeviden...

OpenEvidence, The Ten Billion Dollar Chimera

Is it better, or is it branding?

evidencetriage.com

Do you like using bicarbonate in cardiac arrest? Couldn't hurt! Do you hate using bicarbonate in cardiac arrest? Waste of time! You're both right; never change. #medsky www.evidencetriage.com/p/bicarb-is-...

Bicarb Is Dead ... Or For The Dead?

Let the debates continue!

evidencetriage.com