This was a fun chat with @vickquezada.bsky.social (check out their work at www.vickquezada.art)

Edge Effects@edgeeffectsmag.bsky.social · 3w ago

Artist Vick Quezada and evolutionary biologist Jeffrey Ross-Ibarra join M. Hamilton for Edge Effects' Botanical Imagination series to explore the co-evolution of humans and maíz (corn) through the lenses of cultural history, art and performance, science, and language. 🌽🎙️

📚😅🎉 Yay!! I just submitted the complete manuscript of my upcoming book to the publisher! Learn to easily and clearly interpret (almost) any stats model w/ R or Python. Simple ideas, consistent workflow, powerful tools, detailed case studies. Read it for free @ marginaleffects.com #RStats #PyData

I’ve long used FiveThirtyEight’s interactive “Hack Your Way To Scientific Glory” to illustrate the idea of p-hacking when I teach statistics. But ABC/Disney killed the site earlier this month :( So I made my own with #rstats and Observable and #QuartoPub ! stats.andrewheiss.com/hack-your-way/

Craig Smail wrote up a really nice Preview of @nikhilmilind.dev's paper where we try to explain why large effect variants tend to affect traits in the same direction on average, which we think about in terms of the non-linearity of gene dosage response curves. www.cell.com/cell-genomic...

Gene dosage differences and non-linear impacts on complex traits

Large differences in gene dosage are usually associated with opposite phenotypic effects but show a bias toward one direction in aggregate genome wide. Milind et al. suggest that this is explained by ...

cell.com

Introducing my 1st R package. I built this to address common misunderstandings of linear models i often see in intro biostats students. this is strongly paternalistic and aims to improve students' understanding of intro stats comments welcome yanivjb.github.io/honestlm/ #Rstats #ggplot2 #biostats

Jeremy Hollis’ detective story on centromeric histone chaperones (HJURP/Cal1) is now published after peer review with a few extra goodies. @jeremyahollis.bsky.social @nlehrbach.bsky.social @cbmoens.bsky.social @irinakitop.bsky.social @basicsci.fredhutch.org www.science.org/doi/10.1126/...

Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

Animals encode a rapidly evolving, essential cell cycle gene previously thought to be absent.

science.org

Jeremy Hollis@jeremyahollis.bsky.social · 5mo ago

We have some genetic sleuth work to share with you! What started as a rotation project turned into nothing short of an amazing collaboration between 4 labs in the zoo that is @basicsci.fredhutch.org. We found an essential histone chaperone long thought to be missing in most animals 🕵️‍♂️ bit.ly/4uf8sxz

As our three-month stay in Helsinki comes to an end, I’m leaving with a deeper appreciation for sauna, Moomins, the sea, pine seed development, my family, and especially my collaborator/host/friend @pyhatanja.bsky.social, and her lab members.

How is fertilisation different between flowering plants🌺 and naked-seed plants, like conifers🌳? This illustration has been commissioned by @pyhatanja.bsky.social and Robert Kesälahti and is now freely available on Wikimedia Commons under a CC BY 4.0 licence Link: bit.ly/4w9pyhq 🧪 #SciArt #EduSky

Good news everyone 🥳 Our (w @vincentab.bsky.social) primer on models as prediction machines (with the marginaleffects package) is finally officially published!> journals.sagepub.com/doi/10.1177/...

Models as Prediction Machines: How to Convert Confusing Coefficients Into Clear Quantities - Julia M. Rohrer, Vincent Arel-Bundock, 2026

Psychological researchers usually make sense of regression models by interpreting coefficient estimates directly. This works well enough for simple linear model...

journals.sagepub.com

Coming up in March! Join @sortee.bsky.social for a webinar with @daxkellie.bsky.social on good, shareable, and reproducible R code - register here: events.humanitix.com/sortee-webin...

SORTEE Webinar: On what makes good sharable and reproducible R code, how to do it, and why it’s good for science

For this month's SORTEE webinar, Dr. Dax Kellie from the Atlas of Living Australia will present on good, sharable, and reproducible R code in science

events.humanitix.com

Yo Dawg! I heard you like biorxiv preprints

Stephen Turner@stephenturner.us · 5mo ago

Hey - there's a preprint about the bioRxiv preprint server published as a preprint on the bioRxiv preprint server: bioRxiv: the preprint server for biology www.biorxiv.org/content/10.1...

postd without comment

roses are red why hello tom you predict with a BLUP estimate with a BLUE

I asked chat gpt to rewrite "I’m Comic Sans, Asshole" www.mcsweeneys.net/articles/im-...

Me to students: "Don't just take a screenshot of your R output and paste it in your document, thats unprofessional" NYT to ME:

{livelink} walked so {webrarian} could run. Mini browser-based #rstats environments powered by #webR and its 4-panel editor. YAML config, build, preview. Done. R package coming soon. #pyodide folks, stay tuned.

Congrats @jeffgroh.bsky.social et al. Some avocado trees open female-phase flowers in the morning & then male in afternoon. Others show complementary pattern (m->f), to synchronize pollination of two types. Jeff show this to be a >45Mya polymorphism at a transcription factor across 100s of species.

bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social · 8mo ago

Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado https://www.biorxiv.org/content/10.64898/2025.12.22.695989v1

posted without comment

Available now in @asn-amnat.bsky.social ! Taking on some big-scale natural history: processed >40k @inaturalist.bsky.social images of Monarda fistulosa using computer vision to query for flower presence and phenotype flower color: doi.org/10.1086/739413

High-throughput iNaturalist image analysis reveals flower color divergence in Monarda fistulosa | The American Naturalist: Vol 0, No ja

doi.org

Patrick McKenzie@patrickmckenzie.bsky.social · last yr.

New preprint out today! A really fun collaboration with @shchurch.bsky.social and Robin Hopkins in which we study flower color variation in Monarda fistulosa using iNaturalist data. We process >40,000 images and use them to phenotype flower color in >16,000 observations: doi.org/10.1101/2025...

i dont knoe eho needs to hear this (but someone does) you should not use file.choose() BUT IF YOU DO PLEASE DO NOT PUT IT IN A RMARKDOWN FILE

Crying Pc GIF

ALT: Crying Pc GIF

media.tenor.com

1. We ( @jbakcoleman.bsky.social, @cailinmeister.bsky.social, @jevinwest.bsky.social, and I) have a new preprint up on the arXiv. There we explore how social media companies and other online information technology firms are able to manipulate scientific research about the effects of their products.

Proud of the latest edition of my free intro biostats book. gitrepo: github.com/ybrandvain/b... book: ybrandvain.github.io/biostats/ Not complete but at a good point to take a break, and I think its quite usable dm me with comments , ideas etc

Really excited to share our new paper on #causalinference & #climatechange attribution out in #EcologyLetters today! Are you asking "how much" or "if" climate change has impacted your system, then this paper is for you! 🧪🌏🌐🍁🌺🌱🌿 onlinelibrary.wiley.com/doi/10.1111/...

A Causal Inference Framework for Climate Change Attribution in Ecology

Accurately attributing ecological shifts to climate change remains a significant challenge. Here, we present an accessible causal inference framework designed for climate change attribution in observ...

onlinelibrary.wiley.com

working on my material for next semester. this one ended up on the cutting room floor

Starting now on @Twitch -- twitch.tv/realgoodai I'll be discussing teaching, learning, feedback adn textbooks in the llm era with @RealGoodAi realgoodai.org

Fauci is not exactly Vavilov but Lysenkoists in charge might send him to an El Salvadorian gulag

Two research teams from @cnrs.fr @sbroscoff.bsky.social carried a comparative analysis in flowering plants that supports the prediction that inbreeding, such as self-fertilization, selects for higher recombination rates: doi.org/10.1093/jeb/... Brazier et al. (@romanstet.bsky.social)

Mating system and the evolution of recombination rates in seed plants

Abstract. Meiotic recombination is a central mechanism underlying sexual reproduction among eukaryotes. In many species, the recombination rate is strongly

doi.org

Just made promptdown public. It's a plain-text interface for working with LLMs using literate programming. See and edit the full prompt each turn. No cramped input boxes, no hidden context, no append-only chat. Still early alpha, feedback welcome! github.com/t-kalinowski...

"illustrates how marvellously flexible plant reproductive systems can be." ...discovery that sunflower seeds can develop without fertilization and endosperm (!) 🌾🧪https://www.nature.com/articles/d41586-025-00904-8

Sunflower ‘virgin births’ enable accelerated crop breeding

The discovery that sunflower seeds can develop without fertilization reveals a pathway to accelerate improvement of this crop — and potentially others.

nature.com