I am delighted to announce that our Review article on B cell metabolism is out in Nature Reviews Immunology. We dissect mechanistic and translational developments in the field. Deeply grateful to my co-authors and supervisors @ajclarke.bsky.social, Christoph Hess and Glenn Bantug.

Nature Reviews Immunology@natrevimmunol.nature.com · 5d ago

📢New Review article by @yfy1.bsky.social, @sciencedad24.bsky.social, Christoph Hess & @ajclarke.bsky.social provides a comprehensive 'Guide to B cell metabolism' www.nature.com/articles/s41...

This week in #Science #Immunology: a fantastic paper on #GerminalCenter #BCell #immunometabolism! Check it out!

Hannah Isles@hannah-isles.bsky.social · 2y ago

This week in #ScienceImmunology: Germinal Center B cells require asparagine (Asn) #metabolism for their function. GC B cells can acquire exogenous Asn from their local environment, but when Asn is limited, they utilise the enzyme asparginine synthetase. @ajclarke.bsky.social @yfy1.bsky.social

This week in #ScienceImmunology: Germinal Center B cells require asparagine (Asn) #metabolism for their function. GC B cells can acquire exogenous Asn from their local environment, but when Asn is limited, they utilise the enzyme asparginine synthetase. @ajclarke.bsky.social @yfy1.bsky.social

Asparagine availability controls germinal center B cell homeostasis

Asparagine metabolism is a critical regulator of germinal center B cell function.

science.org

Thrilled to share our latest work on how the non-essential amino acid #asparagine metabolically regulates germinal centers. Huge thanks to my PhD supervisor @ajclarke.bsky.social, colleagues, and collaborators at the @ndorms.bsky.social @ox.ac.uk and @crick.ac.uk www.science.org/doi/10.1126/...

Asparagine availability controls germinal center B cell homeostasis

Asparagine metabolism is a critical regulator of germinal center B cell function.

science.org