Thrilled to share our new paper deriving an ”Exposome Network” of functional connectivity capturing multidimensional env. exposures in youth, now out in DCN! 🌟🧠 doi.org/10.1016/j.dc... Huge thank you Sarah Lichenstein, @yiplab.bsky.social & our amazing Connecticut Collab! ❤️ #devpsy #neuroimaging

Arielle Keller@ariellekeller.bsky.social · 9mo ago

Happy New Preprint Friday!* Thrilled to share new results in collab with Sarah Lichenstein & @yiplab.bsky.social showing our brain's functional connections reflect the environments we grow up in! tinyurl.com/exposomeConnectivity #neuroskyence #PsychSciSky #DevPsy #cognition *can this be a thing??

What a week! #CPC2026 was amazing, and it was such a joy to co-organize & host it here at Yale with @robbrutledge.bsky.social @xiaosigu.bsky.social @yiplab.bsky.social @francesghart.bsky.social & Al Powers & Katie Myerscough (our MVP!) Some highlights... 🧵

…and a powerhouse presentation on modeling of suicidal thoughts from @adanyajohnson.bsky.social #cpc2026 @shirleybwang.bsky.social

Thought provoking talk on analysis of intensive longitudinal data from @teaguerhenry.bsky.social #cpconf2026

Excited for the first day of the annual Computational Psychiatry Conference, this year held at Yale www.cpconf.org! We have a rockstar list of keynote speakers including @danisbassett.bsky.social @adredish.bsky.social and many more! #CPC2026

Computational Psychiatry Conference

New Haven, USA (July 14-16, 2026)

cpconf.org

Is the whole more than the sum of its parts? Considering global and local features of the connectome improves prediction of individuals and phenotypes direct.mit.edu/imag/article...

Is the whole more than the sum of its parts? Considering global and local features of the connectome improves prediction of individuals and phenotypes

Abstract. Popular methods for analyzing the brain’s functional connectome examine statistical associations between pairs of atlas-defined brain regions, viewing the strength of these links as independ...

direct.mit.edu

New this year: free trainee pre-conference on July 13 organized by @cehaeffner.bsky.social @adanyajohnson.bsky.social Pre-conference tickets are free for main conference attendees but space is limited to 75 people so register early! www.cpconf.org/faq-cpconf20...

📣🔥 Early bird registration now open for 2026 Computational Psychiatry Conference cpconf.org at Yale July 14-16. Late-breaking abstracts now open (deadline: May 8) Trainee pre-conference (July 13) registration open (free!) See you in New Haven! #CPConf2026

Computational Psychiatry Conference

New Haven, USA (July 14-16, 2026)

cpconf.org

Our latest work looking at the neuroanatomical basis of impulsivity in youth is out now in Molecular Psychiatry!

Neuroanatomy reflects individual variability in impulsivity in youth - Molecular Psychiatry

Molecular Psychiatry - Neuroanatomy reflects individual variability in impulsivity in youth

nature.com

🚨 New preprint alert! 🚨 Transdiagnostic latent factor models of psychopathology are widely assumed to improve brain-behaviour associations. So we decided to test this directly and found that they don't. A short 🧵 Link: www.biorxiv.org/content/10.6... 1/10

Excited to share our latest paper in which we discuss merging theory-and data- driven computational psychiatry in a large transdiagnostic cohort study (N=2400) www.biologicalpsychiatrycnni.org/article/S245... Christopher Pittenger, Godfrey Pearlson @annierhcheng.bsky.social @sobp-org.bsky.social

Threading the needle: Practical considerations for merging theory-driven computational psychiatry with data-driven analytics to enhance precision health at scale

The rapidly evolving field of computational psychiatry enables quantification of specific cognitive processes, and their underlying mechanisms, in a translational and potentially scalable manner, usin...

biologicalpsychiatrycnni.org

Yesterday we said goodbye to our beloved kitty Coco. We miss her terribly but I am glad I was able to immortalize her in Figures 1 and 2 of my 2021 Synthese paper. Hopefully she will meet Fodor's Greycat in kitty heaven.

Important call for action on the integration of research programs across species. Meaningful progress in the brain sciences will require cross-field collaborations and research that spans human and non-human animal models.

Nanthia Suthana@suthanalab.bsky.social · 6mo ago

The biggest problem holding neuroscience back right now isn’t data or tools, thanks in large part to the BRAIN Initiative. It’s fragmentation across species. I wrote this to hopefully spark discussion around an issue that can only be solved as a community👇 www.thetransmitter.org/animal-model...

Me getting to know a new dataset...

My new chapter of Better Code, Better Science on AI-assisted coding is now complete! It's been completely revised in an attempt to futureproof it. Comments welcome. bettercodebetterscience.github.io/book/ai-codi...

Coding with AI - Better Code, Better Science

bettercodebetterscience.github.io

If you work at the intersection of computational neuroscience and machine learning, consider applying for this postdoc position (January 2027 start date): academicpositions.harvard.edu/postings/15868 An opportunity to work with a great group of people across Harvard, MIT, and UC Berkeley.

Mental health is shaping survival after heart disease—yet we rarely treat it that way. A new meta-analysis of 22 million people links PTSD, anxiety, depression & insomnia with higher risk of acute coronary syndrome. jamanetwork.com/journals/jam...

🌟 Job alert! We are looking for a postdoc to join a multidisciplinary research team working on the Individually Measured Phenotypes to Advance Computational Translation at Yale (IMPACT-Y) study. postdocs.yale.edu/posts/2026-0...

The postdoctoral associate will lead and contribute to the analysis of behavioral task data using computational modeling approaches, working closely with me, @robbrutledge.bsky.social, and with IMPACT-Y leadership, Drs. @yiplab.bsky.social, Chris Pittenger and Godfrey Pearlson.

Neuro friends: Any one ever try tract-tracing studies in the insula or cingulate (in rats or mice) and find a connection there? It keeps showing up in resting-state studies and outside of pIC to pACC inhibitory projections here (pubmed.ncbi.nlm.nih.gov/37605272/), I can't find much else!

Inhibitory insula-ACC projections modulate affective but not sensory aspects of neuropathic pain - PubMed

The insula and anterior cingulate cortex (ACC) are brain regions that undergo structural and functional reorganization in neuropathic pain states. Here, we aimed to study inhibitory parvalbumin positive (PV+) posterior insula (pIC) to posterior ACC (pACC) projections, and to evaluate the effects of …

pubmed.ncbi.nlm.nih.gov

Looking for a postdoc in #computationalpsychiatry? Apply here to join an interdisciplinary team and work with a large longitudinal transdiagnostic dataset postdocs.yale.edu/posts/2026-0... @RobbRutledge @xiaosigu @DrChrisPitt @PearlsonGodfrey @ACNPorg @YaleMed

🔥🔥SAVE THE DATE!!🔥🔥 Join us at Yale for the 2026 Computational Psychiatry Conference July 14-16, 2026 www.cpconf.org @xiaosigu.bsky.social @yiplab.bsky.social @shirleybwang.bsky.social @alpowers7.bsky.social See you in New Haven!

Computational Psychiatry Conference

New Haven, USA (July 14-16, 2026)

cpconf.org

Awesome work here from @ariellekeller.bsky.social er.bsky.social linking the exposome to the developing functional connectome—check it out!! www.biorxiv.org/content/10.1... 1/2

Arielle Keller@ariellekeller.bsky.social · 9mo ago

Happy New Preprint Friday!* Thrilled to share new results in collab with Sarah Lichenstein & @yiplab.bsky.social showing our brain's functional connections reflect the environments we grow up in! tinyurl.com/exposomeConnectivity #neuroskyence #PsychSciSky #DevPsy #cognition *can this be a thing??

Happy New Preprint Friday!* Thrilled to share new results in collab with Sarah Lichenstein & @yiplab.bsky.social showing our brain's functional connections reflect the environments we grow up in! tinyurl.com/exposomeConnectivity #neuroskyence #PsychSciSky #DevPsy #cognition *can this be a thing??

Amazing opportunity to work at the intersection of complex clinical psychiatry and advanced neuroimaging research!!!

Avram Holmes@avramholmes.bsky.social · 9mo ago

Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness? @holmeslab-bhi.bsky.social is hiring! @cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social

Been thinking for a few years about what I call the *replication ceiling*: the maximum replicability of an effect given constraints in data in which replication takes place (power, measurement error, sampling variability, etc). This leads to a maximum theoretical replicability which can be achieved.

Take a look at our paper! Led by @francimandi.bsky.social in the Lake lab: "Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice" !!!! www.biorxiv.org/content/10.1...

Francesca Mandino@francimandi.bsky.social · 9mo ago

Talking about spooky stuff…try to do awake mouse fMRI. Oh, you want it spookier? Try to add simultaneous Ca2+ imaging. Now, do it all again, longitudinally…. So proud to finally have this out!!! 🐭 🧠 🧲 Go read…if you dare!! 👻 www.biorxiv.org/content/10.1...

Really interesting, brief ideas paper. Clearly relevant to treatment research-- the mechanism by which you leave an illness state is unlikely to just be the opposite of the mechanism by which you entered it (can see how this might apply to e.g. SSRIs in depression).

Shirley Wang@shirleybwang.bsky.social · 9mo ago

Thrilled to share a new paper in @jamapsychiatry.com on path asymmetry in complex dynamic systems of psychopathology! jamanetwork.com/journals/jam... With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳

Check out the latest work from this superstar team to learn how you can go from big data to small data with transfer learning to advance precision psychiatry! 🧠

Sarah Yip@yiplab.bsky.social · 9mo ago

Excited to share this review in @biologicalpsych.bsky.social on using transfer learning to leverage large MRI datasets & enhance precision psychiatry!! www.biologicalpsychiatryjournal.com/article/S000... Fun collab with rockstars @diawang.bsky.social @bttyeo.bsky.social @avramholmes.bsky.social

Anybody else worried that because of the long standing Republican war on SNAP people are going to experience painful hunger. Lets do something. @nanopharmnc.bsky.social and i are going to donate to some local nc food banks. Join us! Gonna match up to $500.