Avram Holmes

@avramholmes.bsky.social

Lab website: https://holmeslab.rutgers.edu/

Kudos to @science.org for this self-analysis of the peer review process. These kind of data are never shared and don't have to be. Wildly refreshing to see it out in the open. Editorial and peer review dynamics at elite general science journals | Science Advances www.science.org/doi/10.1126/...

Editorial and peer review dynamics at elite general science journals

Analyses of deidentified data reveal complex interactions that quantify success at elite general science journals.

science.org

My friend and BJJ coach Thiago Brito was picked up by ICE on the way to coach our kid's team at their biggest tournament of the year and needs our help. 30 years in education/coaching, built an amazing community through discipline, compassion, and love. Please share/donate gofund.me/58fcfb35e

Donate to Help Thiago Fight for His Future, organized by Jeffrey Jones

Many of you know Thiago—not just as an incredible Brazilian Jiu-Jitsu instructor, but… Jeffrey Jones needs your support for Help Thiago Fight for His Future

gofund.me

Thank you so much @rutgersbhi.bsky.social for the thoughtful write up of our study that's out now in @natcomms.nature.com!! 🧠

Avram Holmes@avramholmes.bsky.social · 2w ago

Nice write up of @carrisacocuzza.bsky.social's latest work using brain dynamics to study transdiagnostic symptom profiles. @holmeslab-bhi.bsky.social, @rutgersbhi.bsky.social, and @rutgersu.bsky.social. Likely of interest to @hitop-system.bsky.social oriented folks.

A video of a patient who responded well to personalized TMS: www.temasekreview.com.sg/community-st...

temasekreview.com.sg

Thomas Yeo@bttyeo.bsky.social · 2mo ago

Our TMS algorithm is now published in @imagingneurosci.bsky.social doi.org/10.1162/IMAG... If you are coming to @ohbmofficial.bsky.social @ohbmtrainees.bsky.social, come check out our poster about our open label trial. Poster number 1152 Monday, Jun 15 | 14:45-15:45 Tuesday, Jun 16 | 13:30-14:30

Hemispheric specialization is core to brain organization, but its biological basis has been unclear. New @holmeslab-bhi.bsky.social paper links neurochemical & cellular asymmetries to left-lateralized language & right-lateralized attention networks, with implications for evolution & psych illness.

Loïc Labache@loiclabache.bsky.social · last mo.

Happy to share that our work is finally published in @commsbio.nature.com! We identify molecular and cellular signatures of hemispheric specialization, linking language and attention to distinct neurotransmitter, mitochondrial, & cellular organization across the cortex 🧠 doi.org/10.1038/s420...

Happy to share that our work is finally published in @commsbio.nature.com! We identify molecular and cellular signatures of hemispheric specialization, linking language and attention to distinct neurotransmitter, mitochondrial, & cellular organization across the cortex 🧠 doi.org/10.1038/s420...

Molecular and cellular correlates of human cortical lateralization - Communications Biology

Multimodal analyses reveal the molecular and cellular asymmetries underlying human cortical lateralization. Distinct neurotransmitter, mitochondrial, and cellular gradients support left-lateralized la...

doi.org

Loïc Labache@loiclabache.bsky.social · last yr.

🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization 🔗 doi.org/10.1101/2025... 🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇 #neuroskyence

Synaptic loss in schizophrenia isn't random. New PET imaging work from our group, led by @sidchop.bsky.social, shows it's left-lateralized, follows neurochemical gradients, and may propagate outward from inferior frontal cortex through axonal networks, independent of MRI grey matter changes

Sidhant Chopra@sidchop.bsky.social · last mo.

🧠 New work showing prominent and widespread 𝘪𝘯 𝘷𝘪𝘷𝘰 pre-synaptic terminal reductions in people with schizophrenia.🧠 nature.com/articles/s41... Strongest effects in left hemisphere, but synaptic loss didn't track with MRI grey matter alterations, but did align with..👇1/4

Here's bonus slides on cross-validation tests, separate from our preprint. Covering: 1. paired (sign-flip) permutation test 2. label-swap permutation test 3. sample-level vs fold-averaged stats 4. a common misapplication of the corrected t-test 5. three bootstrap variants 1/N

Thomas Yeo@bttyeo.bsky.social · 3mo ago

In a meta-analysis of 210 biomedical AI studies that statistically compared models under cross-validation, 97% used invalid statistical tests. Here's our new preprint doi.org/10.64898/202... led by @tianchu.bsky.social @hetuli.bsky.social @shaoshiz.bsky.social @nichols.bsky.social 1/N