Did you know that fully half of the talks at the Santa Cruz Developmental Biology Meeting this year will be chosen from submitted abstracts? It's true! Great opportunities for trainees and PIs, too! @socdevbio.bsky.social @rashmi-priya.bsky.social @lowelab.bsky.social scdb2026.sites.ucsc.edu

Another awesome iteration of the Santa Cruz Developmental Biology meeting. I can't wait! scdb2026.sites.ucsc.edu

very cool combination of creative experiments and modeling: www.science.org/doi/full/10....

organs develop in a dynamic environment where their boundaries are constantly changing shape, relaxing, compressing, etc. in synchrony with the embryo. see how this inspired us to create a material for optimal organoid bioprinting & self-organization! www.nature.com/articles/s41...

Stress-relaxing granular bioprinting materials enable complex and uniform organoid self-organization - Nature Materials

A tunable granular biomaterial matrix is developed to support long-term bioprinting. Stress relaxation at high strains and long timescales is shown to be important for tissue self-organization in inte...

nature.com

Such an absolute honour 🙏 Thank You @bscb-official.bsky.social Incredibly lucky to be surrounded by the most supportive colleagues and community. This award truly belongs to my wonderful, wonderful lab @crick.ac.uk

British Society for Cell Biology@bscb-official.bsky.social · 7mo ago

We are delighted to announce that @rashmi-priya.bsky.social from @crick.ac.uk has been awarded the 2026 Women in Cell Biology Early Career medal You can read about Rashmi's prize-winning work on heart morphogenesis here: bscb.org/wicb-early-c...

🚨Do sign up to our mailing list for this very exciting joint talk by Profs Marino Arroyo and Xavier Trepat on active morphogenesis on Wednesday 21st Jan🚨

Theory of Living Matter Group@tlmcambridge.bsky.social · 7mo ago

🚨Our first talk this new year would be a joint theory/experiment talk by Prof. Marino Arroyo and Prof. Xavier Trepat @xaviertrepat.bsky.social describing some of their recent work together on active morphogenesis🧫. Sign up to our mailing list for a zoom link to this talk and other upcoming talks🚨

1. Excited to share CONCORD, out in @NatureBiotech, an ML framework for single-cell analysis addressing integration, dimensionality reduction, and denoising in one go by @qinzhu1.🔗 www.nature.com/articles/s41... Check out this CONCORD model of worm development resolving differentiation trajectories:

Mind blown 🤯

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology

McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

nature.com

First, check out my recent bioRxiv preprint w/ @oweinerlab.bsky.social: www.biorxiv.org/content/10.1... We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!

A mechanical origin for implantation defects in embryos from aged females

Women over 35 experience a marked reduction in fertility. The origin of these fertility defects appears to reside in the implantation capacity of the embryo itself, but the mechanistic basis of this i...

biorxiv.org

Very excited to be co-organizing this meeting next February. Fellow collective behavior enthusiasts, this one is for you!

EMBL Events@events.embl.org · 12mo ago

✨ How do bird flocks form or diseases emerge? Join the brand-new EMBO | EMBL Symposium #EESCollectivity and explore how collective behaviours arise from fundamental principles across biological systems 🧬🦠🐒 💻 s.embl.org/ees26-01-bl ✒️ Submit your abstract by 18 Nov

Aria Huang's @azyhuang.bsky.social paper is out on beautiful embryonic kidney 3D cultures that branch properly and enable live defect analysis. She also finds intriguing effects of adhesion and stiffness on explant size, shape, and nephron formation - boundary conditions matter! rdcu.be/eBSUK

🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨ “A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶 🔗 www.biorxiv.org/content/10.1... #devbio #biophysics 🧵⤵️

One month left for ECRs to apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn, @zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys. 📆Apply by 23 May biologists.com/workshops/no... #BiologistsWorkshops

Join us for our next #ForceTalk on "Mechanics of blastocyst morphogenesis" with Dr Jean-Leon Maitre @maitrejl.bsky.social of Institut Curie: 🗓️ 7 May 2025 🕒 15:00 - 16:00 BST Online and open to all, link to join 👉 www.kcl.ac.uk/events/force... #mechanobiology @kingsnmes.bsky.social

Early-career researchers can apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn, @zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys. 📆Apply by 23 May biologists.com/workshops/no... #BiologistsWorkshops

Many congratulations to @jcornwallscoones.bsky.social on the award of a Schmidt Science Fellowship Now he just needs to find a lab to host him for his post-doc www.crick.ac.uk/news/2025-04...

Crick PhD student awarded Schmidt Science Fellowship

Jake Cornwall Scoones, PhD student in the Developmental Dynamics Laboratory at the Francis Crick Institute, has been awarded a prestigious Schmidt Science Fellowship to support his research into how c...

crick.ac.uk

Since I started my PhD in 2013, I have been tantalised by a question: can we measure or evaluate the transcriptional and mechanical states of cells in a tissue at the same time? I pursued this question as a postdoc and then as a PI! A🧵on the answer we have found 👇:

1. Struggling to integrate single-cell datasets? Finding it hard to resolve clear differentiation trajectories? Reveal the underlying structure in your data with CONCORD.

Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social Predictable Engineering of Signal-Dependent Cis-Regulatory Elements www.biorxiv.org/content/10.1... 1/11

Predictable Engineering of Signal-Dependent Cis-Regulatory Elements

biorxiv.org

Congratulations Laura Avinyo! @lauavinyo.bsky.social and Heura Cardona! First paper of your PhD 🎉. doi.org/10.1242/dev.... Beautiful quantified trajectory of how the skeletal pattern of the gene Sox9 emerges during limb development. @embl.org @barcelonacollaboratorium.com

Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀 ▶️ www.science.org/doi/10.1126/...

Material-like robotic collectives with spatiotemporal control of strength and shape

The vision of robotic materials—cohesive collectives of robotic units that can arrange into virtually any form with any physical properties—has long intrigued both science and fiction. Yet, this visio...

science.org

Excited that our new lab website is starting to come together - thanks to the team, particularly Pauline Marangoni and Zhulin Dixon, for assembling this, and stay tuned for additional updates ophirkleinlab.org

Home - Klein Lab

We are interested in understanding how organs form in the embryo and how they renew and regenerate in the adult. We research how development and regeneration

ophirkleinlab.org

Aria Huang's @azyhuang.bsky.social pre-print just came out on effects of adhesion and stiffness on global kidney explant size, shape and nephron forming efficiency. Along the way, she achieves beautiful 3D cultures that retain proper branching geometry, check it out! biorxiv.org/cgi/content/...

Engineering kidney developmental trajectory using culture boundary conditions

Kidney explant cultures are traditionally carried out at air-liquid interfaces, which disrupts 3D tissue structure and limits the interpretation of developmental data. To overcome this limitation, we ...

biorxiv.org

Co-organizing the GRC Mammary Gland Biology and Neoplasia meeting this coming spring in Maine with Traci Lyons. Submit your abstracts for short talk consideration! www.grc.org/mammary-glan...

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...

My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social doi.org/10.1242/dev.... Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....

Right on the $$$

James Briscoe@jamesbriscoe.bsky.social · 2y ago

A stimulating workshop on the subject of Waddington Landscapes in Lyon last week, prompted me to compose some thoughts on dynamical landscapes, gene regulatory networks, and single cell transcriptomics briscoelab.org/morphogenalia/

Hello world!