A nice timeline of the #LTEE in the #MSU Spartan #Science magazine: spartanscience.natsci.msu.edu/evolution-in...
spartanscience.natsci.msu.edu
Aathmaja
@aathmaja.bsky.social
Immigrant, Mom of 2, Microbial Geneticist, Postdocing at Chris Waters lab @ Michigan State University
A nice timeline of the #LTEE in the #MSU Spartan #Science magazine: spartanscience.natsci.msu.edu/evolution-in...
spartanscience.natsci.msu.edu
Professor Bonnie Bassler is awarded the Copley Medal for her discovery of the universality of chemical communication in bacteria and for her idea that interfering with this communication could form the basis of novel anti-bacterials. #RSMedals https://royalsociety.org/medals-and-prizes/copley-medal/
Check out my recent review on the roles of divalent metals in regulating cyclic di GMP signaling in bacteria share.google/LS5Dtk0N9Mgq...
Roles of divalent metals in the regulation of cyclic di-GMP signaling in bacteria | Journal of Bacteriology
Bacteria thrive in a wide range of environments, from soil and water to colonization of host organisms, and they must rapidly adapt to fluctuating conditions to survive and propagate. One of the key m...
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Check out this squid-vibrio postdoc position at Penn State with my colleague Tim Miyashiro, especially if you have a background in proteomics/metabolomics. psu.wd1.myworkdayjobs.com/PSU_Academic...
Postdoctoral Position - BMB
APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...
psu.wd1.myworkdayjobs.com
MGI postdoctoral researcher Dr. Aathmaja Anandhi Rangarajan @aathmaja.bsky.social will be presenting a talk to Biology on Tap on April 2nd entitled "Swim Alone or Stick Together: How Bacteria Decide Their Lifestyle." Join her at 7 pm on 4/2 at the Michigan Wildlife Conservancy!
as many of you know, I'm not Christian but always loved Christmas. My wish: may the light in you and your loved ones shine bright may that light comfort and inspire others may our lights dispel darkness and fear may they give the gift of hope may we walk in light, unafraid, towards what is to be
Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon. blog.genesmindsmachines.com/p/we-still-c...
We still can’t predict much of anything in biology
Biology is hard. Yes, even for AI.
blog.genesmindsmachines.com
New cures feel sudden, but the seeds were planted decades ago by basic scientists. Which seeds will turn into cures? Unpredictable looking forward, a straight line looking back. 🧪🧬 🧵
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
bbc.com
Check out my recent publication on how zinc and quorum sensing affects cyclic di GMP in V. cholerae. share.google/JaOJv48OAhH4...
A cyclic di-GMP phosphodiesterase in the VSP-2 island of Vibrio cholerae is regulated by zinc and quorum sensing | mBio
Vibrio cholerae colonizes estuarine environments and human hosts, where it transitions between motile and sessile states using the second messenger cyclic di-GMP (cdG). cdG levels change in response to a variety of signals and are controlled by the activity of diguanylate cyclases and phosphodiesterase (PDEs), enzymes that make and degrade cdG. In this work, we show that Zn2+ and the cell density regulator HapR repress ZpdA, the PDE present in the Vibrio seventh pandemic 2 island, at the level of transcription, and that Zn2+ unexpectedly alters the PDE activity of ZpdA protein itself. Our study highlights the role of metal availability as an important signaling cue that controls V. cholerae biology.
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I'm back home with my dad and have thoughts about being an Indigenous scientist and academic. I'm writing this in real time so it might get disrupted and will have typos. I am fairly successful by academic standards. I have a tenure track job, wrote papers, have grant funding, mentor students.
Excited to attend my first ASM microbe this year at LA. Will be presenting my postdoctoral work from Waters lab on "Zinc regulation of cyclic di-GMP in V. Cholerae" in Room 408B from 3.30-3.45 on June 20th. Looking forward to seeing you all there. #asm2025
Excited to be representing the Waters lab alongside @aathmaja.bsky.social at #ASMicrobe! Interested how phages use contingency loci as bet hedging strategy? I’ll be talking about this Sat 6/21 from 10-10:15am at “Predicting Microbial Evolution” 403A, LACC
I wrote this in a week where it felt like professoring while parenting (and equally, parenting while professoring) was impossible. This feeling ebbs and flows. Seems like Mothers Day is as good a time as any to share, maybe it will help someone else feel less alone. The More Paradox 1/8
Check out my recent work from Waters lab where we delineated the role of zinc in the regulation of phosphodiesterase that cleave cyclic di-GMP in V.cholerae. thanks to all the collaborators who helped shape this work. www.biorxiv.org/content/10.1...
A horizontally acquired cyclic di-GMP phosphodiesterase regulated by zinc and quorum sensing
The second messenger cyclic di-GMP (cdG) in V. cholerae is indispensable for the regulation of biofilm formation, motility, and a variety of other important bacterial behaviors in the majority of bact...
biorxiv.org