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Alejandro Adam
@aleadam.bsky.social
Cell and #vascular #biologist obsessed with transcriptional control of #inflammation Associate professor at Albany Medical College in Upstate New York. www.adamlabs.org https://orcid.org/0000-0001-6285-7235 #AcademicSky #science #endothelium #shock
Happy to share that we received a long awaited NOA for an MPI R01 with my fabulous colleague and friend @gabbyfredman.bsky.social to study how endothelial cells regulate atherosclerosis progression and stability and how we can leverage resolution mechanisms encoded by ECs to promote plaque stability
Jenna Norton is absolutely right. Thank you for speaking up. @holdenthorp.bsky.social, as someone that grew under a military dictatorship, I can safely say that keeping your head down is not an effective act of resistance. As scientists, we do our work by keeping our head up and speaking the truth.
A problematic stance from someone like @holdenthorp.bsky.social who has the position & privilege that comes with being Editor-in-Chief of Science Journals. Yes, scientists need to continue to do science. But science leaders can't leave the risk that comes with speaking up to others. 🧵1/8
GIFT LINK to this very important news story: share.inquirer.com/sIiF3w
The hidden ICE blueprint that should horrify every American | Will Bunch
An internal Department of Homeland Security document shows how ICE plans to cram thousands of detained human beings inside a Georgia warehouse.
share.inquirer.com
What's more shocking than ICE's plan to cram as many 8,500 humans into massive, soul-crushing warehouses? Seeing the actual DHS floor plan that echoes slavery ships and history's worst gulags with no rec space but a gun range for guards My new column on the camps www.inquirer.com/opinion/ice-...
😲 This is THE most amazing thing I've seen this year. (And that's saying something!) A ResistDance retelling of ICE murdering Renee Good & Alex Pretti enacted through dance‼️😭 Performed by First Amendment Troop in DC. 🤍
I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee.. A few points and new information that bioscientists may find interesting... A 🧵
pretty wild statement re: Republican Chris Madel drop from race for MN governor: "Saying he cannot support the national GOP's 'stated retribution on citizens of our state, nor can I count myself a member of a party that would do so."
NAVBO is joining the January 21st Day of Action to urge increased FY26 funding for medical research! 🧪🫀🔬 ✅ Join us: speak4.app/lp/6t01dslt/... #SupportCures #FundMedicalResearch #CuresCantWait
Make Your Voice Heard!
Both the House of Representatives and the Senate have advanced draft spending bills that maintain federal funding for lifesaving...
speak4.app
Trump joins a not-so-long list of people who have acquired someone else's Nobel medal, including... uh... Joseph Goebbels. www.nobelpeaceprize.org/press/press-...
ROV pilots filmed this giant phantom jelly, or Stygiomedusa gigantea, at 253 meters during an ROV descent to explore the Colorado-Rawson submarine canyon wall. #ArgentinianDeepSeeps
@governor.ny.gov we’re set on one goal in 2026: getting EBRI up & running so New Yorkers get the benefits ASAP after such a hard year for many. EBRI is a transformative investment bringing new medicines & money that can solve other priorities in education, healthcare, transport for the long term.
a cartoon of spongebob reading a piece of paper with the words my new year 's resolutions above him
ALT: a cartoon of spongebob reading a piece of paper with the words my new year 's resolutions above him
media.tenor.com
As a doctor and scientist working to advance health, science, and economic growth in NY, I’m urging @governor.ny.gov to invest in the Empire Biomedical Research Institute to keep the state competitive, sustain jobs, and grow our life science economy. @gothamist.com reports: tinyurl.com/5fab5k7u
NY medical schools press Gov. Hochul to put up billions for scientific research
The request comes amid continuing uncertainty over federal funding, with research and thousands of jobs on the line.
tinyurl.com
Join us in Fort Myers to #connect, #share, and #learn from the leading #DiseaseResearchers at #Pathobiology2026! Submit your abstract and register to save by by January 20 pathobiology2026.asip.org #DiseaseMechanisms #ASIP2026 #CareerDevelopment #PathobiologyResearch
I stumbled across the 300th Episode of South Park, SHOTS!!! One on the most funny/not funny things I have seen in a while. It is about vaccinations and concerns about vaccine hesitancy and that vaccinations cause people to become "artistic". www.youtube.com/watch?v=QZ40...
Cartmans Mum gets a shot
YouTube video by Cat Uploader
youtube.com
Last week, ICE arrested and separated a father and son after a routine check-in. Six-year-old Yuanxin had just enrolled in the first grade at an elementary school in Astoria. Now he's in custody, alone. ICE won't say where. This cruelty serves no one. It must end.
My wife has been HIV+ for 34 years. She’s alive today b/c work of activists who destigmatized the virus, pushed medical science to adapt & find ways to treat it, & advocated for gov health programs that helped fund her care. The current U.S. regime may want to go back in time, but we won’t let them.
Since AI slop is again all over Scientific Reports, a thread on the economics of grey-zone publishing. Why does slop keep getting published? What does it mean for science? How can we stop this? Background readings: Understand the strain: tinyurl.com/2b6wxx5r Stop the drain: tinyurl.com/3jfscscy
Socialism is what they called public power. Socialism is what they called social security. Socialism is what they called the growth of free and independent labor organizations. Socialism is their name for almost anything that helps all the people. —Harry Truman, 1952
This team are searching for new "Asgard archaea" to sequence. Let's talk about why these bacteria-like organisms are so fascinating, why they're named for Norse mythology, and why looking at them is unlocking a better understanding of our own genomes. Once considered a type of oddball bacteria🦠...
#AsgardArchaea team, led by @archaeal.bsky.social fr @texasscience.bsky.social — sequencing the DNA collected fr mouth of Rio de la Plata to the continental shelf of Uruguay to detect Asgards, a group of single-celled organisms & our closest microbial relatives on the tree of life. bit.ly/3MdniTH
So, I have read articles written by people who claim that the entire concept of modern medicine is bad, because "artificially" saving people's lives has put a stop to human evolution by letting genetically inferior people breed. Great that those folks are in charge of the CDC now.
EXCLUSIVE: CDC to end all monkey studies. Decision handed down by recent college grad and former DOGE employee who is now deputy chief of staff at the agency. Animals were being used in studies of HIV prevention. Some may be euthanized. My latest for @science.org
Congratulations Margarida Barroso @barroso8.bsky.social for receiving the Carpenter Ranch Award from @histochemicalsoc.bsky.social ! So well deserved!
I wanted to share probably the most important sermon I’ve given and it’s while I’m being arrested. It’s torture pure and simple what happens at #Broadview. I’m ok, though I was thrown to the ground and choked with my pectoral cross. A review of the video shows I was peaceful - did I deserve this?
Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao. #neuroskyence bit.ly/47MXYLH
Without monkeys, neuroscience has no future
Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.
bit.ly
Previously shared: Systemic shock can lead to vascular dysfunction and organ failure. This issue’s cover features work by Alejandro P. Adam @aleadam.bsky.social showing inflammatory cytokines drives endothelial stress via cytoplasmic DNA. www.jci.org/articles/vie...
Vinculin is a simple adapter protein right? Wrong! That’s been the prevailing view for the 46 years since it was discovered. Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains. www.science.org/doi/10.1126/...
The mechanical response of vinculin
Vinculin buffers force via dynamic domain unfolding/refolding under physiological load and lacks a stable head-tail lock.
science.org
Here's a quick thread with pics summarizing the paper. Many thanks for all the hard work at Albany Med and by our collaborator Pilar Alcaide!
Very proud of this work that is now out on JCI describing a new #signaling pathway downstream of the #cytokine IL-6 in the #endothelium with implications in #sepsis and #shock. Short thread with a summary coming later today. For now just enjoy that gorgeous image taken by my student Fatma Awadalla!