Research Briefings about our paper in Nature Genetics (atlas of human facial development): www.nature.com/articles/s41....

Human facial development atlas illuminates enhancer-based control of facial individuality - Nature Genetics

The facial skeleton is essential for eating, breathing, kissing, speech and personal identity. Our spatiotemporally resolved cell atlas of human embryonic craniofacial development will facilitate a de...

nature.com

Human faces are unique. Though our appearance changes greatly as we age, it is our embryonic development that sets the course for a lifetime of individuality. Read more in our recent publication: www.nature.com/articles/s41...

Atlas of cell types and regulatory elements underlying human facial diversity - Nature Genetics

Single-cell transcriptomics, spatial transcriptomics and chromatin accessibility maps of the human craniofacial region in developing embryos provide insights into the mechanisms underlying facial vari...

nature.com

DNA barcoding systems that uniquely label progenitors allow us to trace their fate. Marine Secchi highlights a #preprint presenting a novel method to analyse complex clonal patterns @sergeyisaev.bsky.social @alekerickson.bsky.social @adameykolab.bsky.social prelights.biologists.com/highlights/c...

Clonal embeddings allow exploratory analysis of lineage-resolved single-cell data - preLights

DNA barcoding systems that uniquely label progenitors allow us to trace their fate. This preprint presents a novel method to analyse complex clonal patterns.

prelights.biologists.com

We are still seeking a postdoc experienced in dev bio to join our lab for a project investigating the epigenetic regulation of cell fate in the early face. Deadline for this call is in few days, so please share this post. www.su.se/download/18....

Stargate SG-1 Season 3 Episode 5 "Learning Curve" is about a planet where the aliens rely solely on nanoscale swarms of robots in brain of a few kids that get lobotomized in order to distribute their knowledge (nanobots) to their society. Without the computers, these aliens were unable to learn.

Does this company's validation blot look like a cut paste job? I can't get over the straight line under the band, subtle difference in background, and what looks like a remnant of another band. Wishing for good HOXA7 antibody for mouse fixed-frozen tissue IHC if anybody knows one...

Our newest paper on mammalian dental evolution, out today as the cover article in @science.org, lead by @narimanechatar.bsky.social with a team of fantastic early career scientists!!! 🎉🥳 “Performance trade-offs define a fundamental dental dichotomy in mammals” www.science.org/doi/10.1126/...

Fluorescence Friday 🔬 By Julia Orio 👏 #FluorescenceFriday #Cells #Microscopy #CellBiology #Cytoskeleton @crg.eu @prbb.org

New favorite way to color code microscopy data: this is a real 3D confocal image of an unidentified larvae stained for actin (muscles fibers here). Looks like a watercolor painting! #microscopy #ImageJ #FluorescenceFriday #microscopyMonday

Grateful to the Swedish Hjärnfonden for supporting our lab's project (in collaboration with Emma Andersson) in which we will attempt to gain a deeper understanding of the signaling and regulatory mechanisms underlying brain-face co-variation in mammals. Thank you!

We are seeking a motivated postdoc to join our lab at Stockholm University for a 2yr project investigating how GRNs shape the developing face using high-throughput fate mapping and perturbations. Experience with in vivo models, functional genomics, and bioinformatics are a plus. Let me know!

And universities are being further gutted by new rules requiring 'temporary' visa holders (mist academics come on J or H1Bs) to return to their home countries to apply for green cards. Our universities are being torn apart. This will affect at least 5 people on my immediate projects.

Green Card Processes and Procedures | USCIS

Each Green Card category have specific steps and procedures to follow. Listed below are some general processes and procedures to help you apply either while in the United States (known as “adjustment ...

uscis.gov

Carl T. Bergstrom@carlbergstrom.com · 4mo ago

“Units of the NIH are privately directing grantees to request permission in advance for any co-authorship with a scholar affiliated with a foreign institution, even if all the work was done in the United States.” Grantees also told to remove papers with foreign authors from progress reports.

Happy #FluorescenceFriday! I captured this shot of a group of embryonic macrophages expressing LifeAct and H2B migrating inside tissue. These cells can use lamellipodia, filopodia, or blebs to migrate, and are frequently switching between these different modes or combining them. So fascinating.

A day in the life of a growing hiPSC spheroid expressing endogenously mStayGold-tagged histone 3.3 for #FluorescenceFriday and the #Snouty aficionados. 28 hours (and >50,000 exposures) later and they are still going! Home-brewed volume projection.

Jane Fisher (American Artist, born 1961) "Untitled (Woman on Underwater Steps)", 1989. Oil on Canvas, 48 × 62 inches. Private Collection. #art #painting #artist #BlueSkyArt

During morphogenesis, different tissue interacts with one another, either mechanically or biochemically. Patrick P.L. Tam and Pragathi Masamsett show that the anterior mesendoderm can pattern head formation in mouse embryos by regulating WNT signalling. Check it out here: doi.org/10.1016/j.cd...

Reptiles with longer Wikipedia pages tend to be bigger. The relationship is a power law with exponent = 0.85. I guess humans really like writing about big lizards? The longest article is the Komodo Dragon.

140,000 fake citations in 2025 alone 😱 www.nature.com/articles/d41...

Hallucinated citations highest in social sciences preprints site

More than 140,000 fake citations across four research repositories were identified in papers and preprints published in 2025 alone.

nature.com

Ukrainian artist, Olga Grigoreva Klimova Self portrait

The extent of “photoshop artistry” at play is appalling. These antibodies might as well work just fine, but it really erodes the trust when there is a systematic effort into lying.

Sholto David@sholtodavid.bsky.social · 4mo ago

Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!

'We primarily do comparative analysis using human stem cells/organoids and genetically modified mouse models, with some minor use of frog models. We use this approach because, for developmental anomalies, it is impossible to assess true function without in vivo models' @karenjliu.bsky.social

Why in vivo models of disease remain indispensable

Summary: The call to arms for alternatives to model organisms of disease will fail without ongoing integration with – and validation against – complex animal models and support from the animal modelli...

journals.biologists.com

Clipping lost on roundtrip to tiny

Have you recently (or nearly) defended your PhD and are interested in gene regulatory networks (GRNs), cell fate decisions, and the evolution of skeletal form? Let's apply together for the Wallenberg DDLS Postdoc Call 2026 (deadline for this is March 31). 1/n www.scilifelab.se/data-driven/...

DDLS Research School Postdoc call 2026

Call for Academic and Industrial Postdoctoral Fellowships in Data-Driven Life Science 2026 Generic Description of the DDLS Postdoc Program The SciLifeLab and Wallenberg National Program for Data-Drive...

scilifelab.se

Thanks to both the Petrus och Augusta Hedlunds Stiftelse, and the Åke Wiberg Stiftelse, for their generous decisions in 2025 to support my group's research into molecular mechanisms of brain-face covariation and birth defects affecting the facial skeleton.

A Cooper's Hawk getting escorted out of the air space by a Barn Swallow.

In our latest #SETILive #podcast, artist Jennifer Willet talks about the experience of creating an artwork that represented the seemingly opposing viewpoints of biogenesis from our two 2025 Drake Award winners. Listen to the full podcast: www.seti.org/seti-live/ 🧪 👩‍🔬 🐡

looks useful

Yogesh Goyal@goyallab.bsky.social · last yr.

Excited to share our latest by my postdoc Ben KS: we use statistical physics & Bayesian inference to model genome-wide perturbation outcomes. Remarkably, perturbation responses are encoded in gene "chatter" even before the perturbation–a fundamental insight with broad implications shorturl.at/2LHbw

www.science.org/doi/10.1126/...

Superstable lipid vacuoles endow cartilage with its shape and biomechanics

Conventionally, the size, shape, and biomechanics of cartilages are determined by their voluminous extracellular matrix. By contrast, we found that multiple murine cartilages consist of lipid-filled c...

science.org

pubmed.ncbi.nlm.nih.gov/38294852/

N-cadherin and β1 integrin coordinately regulate growth plate cartilage architecture - PubMed

Spatial and temporal regulation of chondrocyte maturation in the growth plate drives growth of many bones. One essential event to generate the ordered cell array characterizing growth plate cartilage ...

pubmed.ncbi.nlm.nih.gov