Alexander Huth

@alexanderhuth.bsky.social

Interested in how & what the brain computes. Professor in Neuroscience & Statistics UC Berkeley

Really excited about our new work on aphasia! Even in fairly profound aphasia, we can recover semantic maps through visual stimuli and use them to decode language. This is a big step! Language BCIs in aphasia might be possible!

@jerrytang.bsky.social · 4mo ago

We're excited to share our new study on decoding brain activity in participants with post-stroke aphasia! We think this is an important step towards cognitive brain-computer interfaces for patients with language disorders www.biorxiv.org/content/10.6... 1/8

Thank you for your responses, Valentin! On this: I tried to match the contrast values to your results — the "true" ΔCBF is based on your reported 7.7% from Table S1; others are from Figure 2b,c. The noise-free simulation shows ΔCBF ranging from -7..7%, well within the -15..30% range in your Fig. 3b.

Valentin Riedl@vavatin.bsky.social · 7mo ago

MRI-data are noisy, but your simulation uses error-terms and SNRs beyond real data quality (i’d guess your CBF signal is around 5x weaker than imaging data, the real T2* changes are around 5x higher), so sure, you’ll easily (intentionally?) get more noise propagation.

This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!

Eiko Fried@eikofried.bsky.social · 7mo ago

Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity. www.nature.com/articles/s41...

📣 New preprint from the Braga Lab! 📣 The ventral visual stream for reading converges on the transmodal language network Congrats to Dr. Joe Salvo for this epic set of results Big Q: What brain systems support the translation of writing to concepts and meaning? Thread 🧵 ⬇️

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New Open dataset alert: 🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience! N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks! 🧵below

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New paper with @rjantonello.bsky.social @csinva.bsky.social, Suna Guo, Gavin Mischler, Jianfeng Gao, & Nima Mesgarani: We use LLMs to generate VERY interpretable embeddings where each dimension corresponds to a scientific theory, & then use these embeddings to predict fMRI and ECoG. It WORKS!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Evaluating scientific theories as predictive models in language neuroscience https://www.biorxiv.org/content/10.1101/2025.08.12.669958v1

In our new paper, we explore how we can build encoding models that are both powerful and understandable. Our model uses an LLM to answer 35 questions about a sentence's content. The answers linearly contribute to our prediction of how the brain will respond to that sentence. 1/6

The preprint of my 1st project in grad school is up 🙌 We propose a simple, information-theoretic model of how humans remember narratives. We tested it with the help of open-source LLMs. Plz check out this thread for details ➡️ Many thanks to my wonderful advisors! It's been a fun adventure!!

Alexander Huth@alexanderhuth.bsky.social · last yr.

New paper with @mujianing.bsky.social & @prestonlab.bsky.social! We propose a simple model for human memory of narratives: we uniformly sample incoming information at a constant rate. This explains behavioral data much better than variable-rate sampling triggered by event segmentation or surprisal.

New paper with @mujianing.bsky.social & @prestonlab.bsky.social! We propose a simple model for human memory of narratives: we uniformly sample incoming information at a constant rate. This explains behavioral data much better than variable-rate sampling triggered by event segmentation or surprisal.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Efficient uniform sampling explains non-uniform memory of narrative stories https://www.biorxiv.org/content/10.1101/2025.07.31.667952v1

Hey, if you need a breather from the news, we have pretty brain pics to distract you! We made an interactive viewer showing images optimized to elicit responses from different places in the brain. Link to viewer in 🧵

Mark Lescroart@neuromdl.bsky.social · last yr.

In a new paper led by @matthewshinkle.bsky.social, we use a pre-trained deep neural network (DNN) to model brain activity and to make detailed visualizations of feature selectivity across many brain areas. In plain English: we make pretty pictures of what different parts of the brain like to see.

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Many cognitive neuroscientists ignore the cerebellum but it's long past time to pay more attention to it (and fund more cerebellum grants). Not just for basic science: the cerebellum is commonly affected by pediatric brain tumors, leading to lifelong motor AND cognitive deficits. Must-read paper 👇🏼

Ignoring the cerebellum is hindering progress in neuroscience

Traditionally considered a motor structure, the cerebellum has been shown to play a key role in several cognitive functions. However, for decades, the…

sciencedirect.com

Very pleased to share our recent work, in which we use LLMs for automated discovery of interpretable models of animal behavior 🪰🐀🕵️‍♀️ that take the form of Python programs 🐍 See below for a summary of key results by @pcastr.bsky.social!

Pablo Samuel Castro@pcastr.bsky.social · 2y ago

Can LLMs be used to discover interpretable models of human and animal behavior?🤔 Turns out: yes! Thrilled to share our latest preprint where we used FunSearch to automatically discover symbolic cognitive models of behavior. 1/12