Andrea Galmozzi @andreagalmozzi.bsky.social @uw-medicine.bsky.social and co-workers show that white and brown #adipose tissues share a convergent fibro-adipogenic progenitor population. #metabolism www.embopress.org/doi/full/10....

RESEARCH | ‪@dylanduerre.bsky.social @andreagalmozzi.bsky.social‬ et al. - ‪@uwmadison.bsky.social‬ Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which impairs #thermogenesis 🐁🌡️ www.nature.com/articles/s42...

Haem biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue - Nature Metabolism

Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which reduces UCP1 levels and impairs thermogenesis.

nature.com

Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social

Dylan Duerre@dylanduerre.bsky.social · last yr.

Excited to share that work from my PhD is now available in @natmetabolism.bsky.social! Here, we uncover a link between heme production, BCAA metabolism, and thermogenesis—implicating heme synthesis in #aging, #obesity, and #T2D. Link to paper: urldefense.com/v3/__https:/... A Thread (1/15)

Here in @cellmetabolism.bsky.social we come together as a community to share our ideas and propose experiments to help resolve ongoing debates in the field of adipocyte #thermogenesis. @mcgillgci.bsky.social www.cell.com/cell-metabol...

Pleased to announce the publication of our new manuscript, "Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging" in Nature Aging today! www.nature.com/articles/s43... Free link: rdcu.be/d1DGk

Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging - Nature Aging

Yeh et al. explore the effects of restricting dietary protein, or isoleucine specifically, in aged mice. They uncover benefits to metabolic health and certain indicators of aging and a sexually dimorp...

nature.com

🚨 Tenure track positions at Physiology Dept UMN. Join a vibrant research environment: med.umn.edu/physiology med.umn.edu/aging med.umn.edu/about/center... Areas of interest: aging biology, molecular metabolism, cardiovascular, inflammation, stress etc. Apply here: z.umn.edu/9zxj