Andrew Lin

@andrewclin.bsky.social

Neuroscientist studying olfaction

Birds have a thick retina devoid of blood vessels - so how do they ensure sufficient oxygen availability? They don't - neurons rely on glycolysis, metabolizing glucose released from the pecten. Insane new study that includes comparative data on lizards and crocs.🧪 www.nature.com/articles/s41...

Oxygen-free metabolism in the bird inner retina supported by the pecten - Nature

While the photoreceptor outer segments in the bird outer retina have access to oxygen, the inner retina operates under chronic anoxia, supported by anaerobic glycolysis in the retinal neurons.

nature.com

Step into a Europe-wide community of neuroscience leaders. Junior & mid-career group leaders: apply by 30 Jan to become a FENS-Kavli Network Scholar and connect, collaborate, and contribute to shaping neuroscience in Europe. rb.gy/havqur

Bild

How is valence computed in the brain? Check out our new preprint about a single cell that integrates excitatory and inhibitory input across modalities according to valence and impacts behavioral decisions. An exciting collaboration across many labs. Enjoy reading! www.biorxiv.org/content/10.1...

A multisensory, bidirectional, valence encoder guides behavioral decisions

A key function of the brain is to categorize sensory cues as repulsive or attractive and respond accordingly. While we have some understanding of how sensory information is processed in the sensory pe...

biorxiv.org

Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...

Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells

Abstract figure legend: We tested the effects of expressing the bacterial voltage-gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expressi...

doi.org

Dear All, I believe that this thread will become one of my most important contributions to the fly field (I hope I will make other contributions)! Here, I introduce the Soy Milk Machine Fly Food Method, a.k.a., DeepCook!#Drosophila#NewPI

Bild

This article shows that "non-responsive" neurons can still add to the Fisher Info about object location in the midbrain of weakly electric fish: www.jneurosci.org/content/45/3... Brings me back to one of my usual bugbears in #neuroscience, i.e. don't judge a cell's function by its tuning curve! 🧪

Nonresponsive Neurons Improve Population Coding of Object Location

Understanding how heterogeneous neural populations represent sensory input to give rise to behavior remains a central problem in systems neuroscience. Here we investigated how midbrain neurons within ...

jneurosci.org