youtube.com/shorts/zp2dS... New on YouTube - is crit care board certification the Skeleton Key to better patient outcomes? Join me on YouTube to learn more and expect another video on Thursday!
Andrew DeSio BBBBCCCCCCCIDPPPPS
@andrewdesio.bsky.social
Crit Care, ID, Cards, whatever! Still the Super Saiyan of pharmacy! Catch me on YouTube! - https://youtube.com/@ketaminerx?si=yYbBgVKMvKDbxG8A
New gram negative guidance!? Already? I’ll take it! But where’s the updated pdf? Will have to break this one down! www.idsociety.org/practice-gui...
🔥Just published 🔥NEJM SNAP RCT In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky www.nejm.org/doi/full/10....
Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia | NEJM
Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ...
nejm.org
What happens when the mortality benefit of a miracle sepsis drug suddenly… disappears? Join me for a quick discussion on Xigris and the origins of Surviving Sepsis! youtube.com/shorts/DK98X...
Xigris, Eli Lilly, and the Surviving Sepsis Marketing Machine
YouTube video by KetamineRx
youtube.com
EPIC-Fail - why is the EPIC Sepsis Model HORRIBLE at detecting sepsis? youtube.com/shorts/bWA21...
EPIC Fail - Why is the EPIC Sepsis Model so HORRIBLE at Detecting Sepsis?
YouTube video by KetamineRx
youtube.com
This guy shows up to your emergency department, and the trauma team is asking for antibiotic recs. So, what do we cover with, and for how long? Join me on YouTube for a quick discussion on antibiotics for penetrating brain injuries! youtube.com/shorts/TsW3d...
youtube.com/shorts/MpcQh... This was a fun one to research! How to treat hydrofluoric acid burns in a few minutes!
So You're Dissolving In A Barrel Of Hydrofluoric Acid... Now What?
YouTube video by KetamineRx
youtube.com
youtu.be/Iv8bWucZapg?... Hey gang! Join me on YouTube for a deeper discussion on the data behind phenylephrine for septic shock! Full video is out now!
Feeding on pressors? Probably! Join me on YouTube for full videos, or Instagram and TikTok (KetamineRx everywhere) for more shorts like this!
Stop by my YouTube and let's chat about PIPPEN - Is it time for to go There And Back Again with Pip-Tazo, or do we leave it back at Bag End until there's more data?
The PIPPEN Trial - A Second Breakfast for Zosyn in Penicillin-Allergic Patients?
YouTube video by KetamineRx
youtu.be
Howdy BlueSky! Started a YouTube channel recently to share knowledge and have a little fun learning to shoot and edit videos! Stop by and check it out if you're interested, got a few videos up now! youtu.be/lRfe96SQp5Y?...
I Survived Surviving Sepsis 2026 - Was it Worth it?
YouTube video by KetamineRx
youtu.be
Just gotta say how much I appreciate simple little studies like this that save a lot of wasted energy looking for alternatives for patients that need meds while breastfeeding. So simple yet so reassuring. pubmed.ncbi.nlm.nih.gov/39405564/
Investigating the Transfer of Lisinopril Into Human Milk: A Quantitative Analysis - PubMed
Lisinopril is commonly prescribed to manage conditions such as hypertension and heart failure. Although concerns about fetal toxicity have traditionally limited the use of lisinopril in women of repro...
pubmed.ncbi.nlm.nih.gov
It’s true what they say about reviewer 2! Time to fix up these manuscripts and resubmit, womp womp
Enjoying a nice comfy break from social media and capturing a couple top 3 finishes while that’s still achievable! Gotta get better about coming back here, feel like I’m just not as caught up with the latest lit these days!
These won’t last, but I’ll take the Ws and podiums when I can!
Is fifth third just like, the worst bank?
Dang, first manuscript rejected from JTACS. At least lots of helpful feedback, hopefully we can rework things a bit and get it accepted somewhere. Fingers still crossed on the prospective paper, hopefully that one makes it!
Finally! Antibiotics are not non-inferior to appendectomy despite a generous 20% non-inferiority margin They are actually inferior: www.thelancet.com/journals/lan... in the @thelancet.bsky.social #MedSky
Also I must have misremembered, this study found a cut-off of 284 WBCs for older women with UTI academic.oup.com/cid/article/...
Current Pyuria Cutoffs Promote Inappropriate Urinary Tract Infection Diagnosis in Older Women
The degree of pyuria can help distinguish urinary tract infection (UTI) in older women from asymptomatic women with and without bacteriuria. We demonstrate
academic.oup.com
Love this since every lab I’ve seen has topped out at 200+! Think my current one is 180+, with abnormal lab reported at >8 😢
Jonathan Ryder, MD@jonathanrydermd.bsky.social · 2y agoMaybe! I'm glad they studied this, as its an often excluded population. 10 WBCs isn't hard to generate in the urine (e.g., in older women, the cut-off should probably be like 600+), so if someone really has a UTI, you might still get some inflammation albeit less than others?
Important article for #AMSSky, #TxID, #UTISky, and #IDSky in @cidjournal.bsky.social: In neutropenic & non-neutropenic cancer patients w/ & w/o catheters, the absence of nitrite/leukocyte esterase or WBC<10 had high NPV for clinically significant bacteriuria academic.oup.com/cid/advance-...
🆕💫Multicenter retrospective study @cidjournal.bsky.social Impact of Fluconazole Resistance on the Outcomes of Patients With Candida parapsilosis Bloodstream Infections #idsky #EMIMCC academic.oup.com/cid/advance-...
Impact of Fluconazole Resistance on the Outcomes of Patients With Candida parapsilosis Bloodstream Infections: A Retrospective Multicenter Study
Despite global concerns about fluconazole resistance in Candida parapsilosis, its impact on mortality remains unexplored. Our study found no increased mort
academic.oup.com
NEW PREPRINT! Enjoyed working with @tom-parks.bsky.social and @petedodd24.bsky.social on immortal time bias In its simplest form, ITB results from misallocation of person time, i.e. pre treatment time in intervention group being counted as time on treatment www.medrxiv.org/content/10.1... [1/n]
Recent studies reinforce the benefits of oral antibiotics, as well as shorter durations of therapy in BJIs with supporting evidence 🆕💫 Review article Bone Voyage: Navigating Updates in the Management of Bone and Joint Infections #idsky link.springer.com/article/10.1...
Bone Voyage: Navigating Updates in the Management of Bone and Joint Infections - Current Infectious Disease Reports
Purpose of Review Advancements in the management of bone and joint infections (BJIs) aim to improve outcomes while challenging long-standing treatment practices. This review discusses key updates, inc...
link.springer.com
What a cool study and a powerful demonstration that Tuberculosis is largely a disease of poverty. In Brazil a large scale intervention which provided cash monthly to families living in poverty led to profound reductions in TB cases. Up to 50% among the poorest groups. www.nature.com/articles/s41...
Effects of conditional cash transfers on tuberculosis incidence and mortality according to race, ethnicity and socioeconomic factors in the 100 Million Brazilian Cohort - Nature Medicine
Participation in Brazil’s Bolsa Familia Program, one of the largest conditional cash transfer programs in the world, was associated with large reductions in tuberculosis incidence and mortality among ...
nature.com
Though "Oral is the New IV" with antibiotics (h/t @bradspellberg.bsky.social), it's not always easy to convince reluctant inpatient clinicians -- especially (in my experience) surgeons, who want to treat "aggressively". Interesting dynamic ... blogs.jwatch.org/hiv-id-obser...
On the Inpatient ID Consult Service, Oral Antibiotics Have a Rocky Road to Acceptance
Having just completed a stint doing inpatient ID consults, I came away impressed with three things: Staph aureus remains the Ruler of Evil Invasive Pathogens in the hospital setting. You can “jinx” a ...
blogs.jwatch.org