Arjuna Rajakumar PhD

@arjunarajakumar.bsky.social

EvoDevo biologist - Post Doc Lehmann lab Whitehead Institute ants + flies germ cells, eusociality & endosymbisis

Excited to share some of our new work on Queen and Worker caste determination in ants!! Especially, the surprisingly role early embryonic development plays!

Virtual Gastrulation Zoom Talks@vgzt2021.bsky.social · 7d ago

🐜 Ant societies meet embryonic mechanics! Join @arjunarajakumar.bsky.social and @surajshankar.bsky.social for two fascinating talks exploring caste determination and robust fate timing. 📅 Oct 2 | ⏰ 10 AM ET / 7 AM PT 🔗 Scan the poster’s QR code to join us and bring your questions! #evodevo #dev

One of the best studied places in Drosophila and they find stunning new things. Biology never stops giving 🧪

Arjuna Rajakumar PhD@arjunarajakumar.bsky.social · 3w ago

So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8 www.biorxiv.org/content/10.6...

Drosophila stage 10b embryo w/HCR staining marking two germ cell clusters. One will successfully colonize the gonad and the other, like tears in the rain, will be lost forever

This work would not have been possible without the incredible snATAC-seq atlas of the Drosophila embryo from @diegoisworking.bsky.social @jshendure.bsky.social and @eileen-furlong.bsky.social which helped us discover that germ cells retain a totipotent chromatin state throughout development!

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Arjuna Rajakumar PhD@arjunarajakumar.bsky.social · 3w ago

So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8 www.biorxiv.org/content/10.6...

Drosophila stage 10b embryo w/HCR staining marking two germ cell clusters. One will successfully colonize the gonad and the other, like tears in the rain, will be lost forever

Incredibly excited to share my new preprint! 🪰🧬 Ever wondered how germ cells can specify their fate without having a dedicated transcriptional program? We found that germ cells keep the uncommitted chromatin state of the early embryo www.biorxiv.org/content/10.6...

Decoupling Transcription from Cell Fate Preserves Germ Cell Totipotency

Only germ cells can give rise to a totipotent embryo, yet a conserved transcriptional program for germ cell identity remains elusive. Profiling Drosophila primordial germ cells (PGCs) across embryogen...

biorxiv.org

Polyphenism - one genome producing different forms - is common in eusocial insects. @arjunarajakumar.bsky.social explores the molecular basis for Pharaoh ant caste development. Queens produce two egg types, giving rise to fertile queens or sterile workers, & queen:worker changes over time. #2026SDB

Excited to announce the Arsenault Lab is launching this fall at Mississippi State! We'll be using ants as a model to tackle fundamental questions in evolutionary biology and evo-devo through genetics and genomics techniques. Please reach out if you're interested, or share with someone who might be!

Please don’t stop sharing and posting your science because of the current attack on it, it is still valuable and reminds us what the fight is for

Incredibly excited to rejuvenate my scientific social network on Bluesky! Current and past research interests include germline immortality, protein folding and organelle remodeling during development. Looking forward to what lies ahead!