Mom does know best; her gut microbial community plays a central role in establishing the infant microbiome. This paper is a fresh look at uniparental transmission of gut microbes.

Trishla Sinha@trishlasinha.bsky.social · 2d ago

1/12 After years of work, we are incredibly excited to share our study, published yesterday in @nature.com : “Maternal influences on gut microbiome and health” 🎉🦠 www.nature.com/articles/s41... A thread on what we found 🧵👇

🚨Out now!! A big congratulations to everyone for this huge effort! Read the highlights below! 👇🏻

Trishla Sinha@trishlasinha.bsky.social · 2d ago

1/12 After years of work, we are incredibly excited to share our study, published yesterday in @nature.com : “Maternal influences on gut microbiome and health” 🎉🦠 www.nature.com/articles/s41... A thread on what we found 🧵👇

🚨 Our new study on the maternal and infant gut microbiome is now published in @nature.com ! 🧬 A big congratulations to all the authors and collaborators involved in this work! 🙌 Huge thanks to all participating families for making this research possible. 💛 🔎 Read the highlights below 👇

Trishla Sinha@trishlasinha.bsky.social · 2d ago

1/12 After years of work, we are incredibly excited to share our study, published yesterday in @nature.com : “Maternal influences on gut microbiome and health” 🎉🦠 www.nature.com/articles/s41... A thread on what we found 🧵👇

1/12 After years of work, we are incredibly excited to share our study, published yesterday in @nature.com : “Maternal influences on gut microbiome and health” 🎉🦠 www.nature.com/articles/s41... A thread on what we found 🧵👇

Maternal influences on infant gut microbiome and health - Nature

The maternal gut microbiome is a predictor of infant eczema.

nature.com

📢 Applications open! Join us for our upcoming Viromics Workshop! 🧬 Learn cutting-edge metagenomic assembly, viral identification, and annotation pipelines. 🗓️ Dates: Oct 14-16 ⏰ (Extended) Deadline: Aug 20, 2026 🔗 Apply here: forms.gle/pJFLDCNEBvAe... #Viromics #Bioinformatics #AcademicSky

Last week, members of the Groningen Microbiome Hub participated in the 𝗗𝘂𝘁𝗰𝗵 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲 𝗗𝗮𝘆 𝟮𝟬𝟮𝟲 held at the @umcgroningen.bsky.social, joining researchers from across the Netherlands to share the latest developments in microbiome science.

Happy to have presented my poster on our findings from the maternal and early-life gut virome in the Lifelines NEXT cohort at #IHMC2026 last week. It was also a pleasure to explore South Korea 🇰🇷 with members of @gromicrobiome.bsky.social #HumanMicrobiome #Virome @ihmc2026seoul.bsky.social

New week, new conference! 🇰🇷 Excited that our team will be strongly represented at the #IHMC Conference in Seoul from 3–5 June. @ihmc2026seoul.bsky.social If you're attending, here’s where you can find us 👇 #IHMC2026 #HumanMicrobiome #MicrobialGenomics #Virome #ComputationalBiology #HumanHealth

We had an amazing time at #ViBioM2026 last week in Vilnius 🇱🇹🤝 Researchers from around the world shared insights on virus #metagenomics, #phylogeny, protein & RNA biology, and #ML approaches. Huge thanks to all organizers, helpers, and our sponsors (GoVilnius, Viruses/MDPI, @febsopenbio.bsky.social)!

🌟 Day 1 of #ViBioM2026 at Vilnius University 🏛️ with a warm welcome by Manja, Gytis, and Ingrida – we already feel at home! Excited to start a full programme of talks, posters, and discussions on computational approaches in #virology. #viralgenomics #datascience #virusevolution

Oxidative stress constrains evolution of bacteriophage host-range diversity academic.oup.com/ismej/advanc... #jcampubs

🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...

Diversity-generating retroelements for programmable targeted hypermutagenesis - Nature Biotechnology

Diversity-generating retroelements are engineered for directed evolution in E.coli.

nature.com

Excited to share that our review: “𝗧𝗵𝗲 𝗶𝗻𝗳𝗮𝗻𝘁 𝗴𝘂𝘁 𝘃𝗶𝗿𝗼𝗺𝗲: 𝗸𝗻𝗼𝘄𝗻𝘀, 𝘂𝗻𝗸𝗻𝗼𝘄𝗻𝘀, 𝗮𝗻𝗱 𝗮𝘃𝗲𝗻𝘂𝗲𝘀 𝗳𝗼𝗿 𝗳𝘂𝘁𝘂𝗿𝗲 𝘀𝘁𝘂𝗱𝗶𝗲𝘀” written together with Nataliia Kuzub has just been published in 𝗘𝗻𝗴𝗶𝗻𝗲𝗲𝗿𝗶𝗻𝗴. Check the 𝗽𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 here and see the thread below: 👇 doi.org/10.1016/j.en...

Now online! Phages communicate across species to shape microbial ecosystems

Phages communicate across species to shape microbial ecosystems

Gallego-del-Sol et al. show that arbitrium-coding phages can sense non-cognate peptide signals from other phages to regulate lysis-lysogeny decisions. This crosstalk affects lysis-lysogeny outcomes of phage infections, mixed lysogenic communities, and polylysogens. Our results demonstrate that crosstalk is an important mechanism that drives phage interactions in microbial communities.

dlvr.it

Have you developed a new #bioinformatics tool to understand #phage or #virus? Make sure you add it to #awesome-virome github.com/shandley/awe...

Whenever I presented Phold, I was frequently asked "can you do the same beyond phages?" We ( @oschwengers.bsky.social @linsalrob.bsky.social @binomicalabs.org et al) finally did it with Baktfold github.com/gbouras13/ba... www.biorxiv.org/content/10.6...

Finally out! 🥂 link.springer.com/article/10.1... We used 3 different methods to profile fecal DNA and analysed how gut microbiome composition and human cell fractions define disease severity in IBD pediatric patients. Many thanks to my supervisor Moran Yassour and our collaborators 🧵⬇️

Human DNA levels in feces reflect gut inflammation and associate with presence of gut species in IBD patients across the age spectrum - Microbiome

Background Feces represent a complex biological matrix that provides valuable information about intestinal physiology and gut microbial activity. Comprehensive fecal DNA sequencing is mostly utilized ...

link.springer.com

Our team is very well represented at 𝗠𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝗺𝗲 𝘁𝗼 𝗟𝗶𝗳𝗲 conference this week! Here’s where you can find us 👇 𝗧𝗵𝘂𝗿𝘀𝗱𝗮𝘆, 𝗠𝗮𝗿𝗰𝗵 𝟭𝟵 – Session 1 🍼 𝗧𝗿𝗶𝘀𝗵𝗹𝗮 𝗦𝗶𝗻𝗵𝗮: "Mom Matters: Maternal influences on infant gut microbiome and health in 714 mother-infant pairs in the Lifelines NEXT cohort"

RNA virus Journal Club is on! 🌳March 17th | Tuesday, 10 AM Berkeley time / 18 PM CET 🕰️ You've probably heard about the meta-virus resource? We will get to dive into metaVR database & huge viral diversity within thanks to @mattlabguy.bsky.social 🥳 All welcome! Details ⬇️ @rdrpsummit.bsky.social

Updated link to the 𝗟𝗶𝗳𝗲𝗹𝗶𝗻𝗲𝘀 𝗡𝗘𝗫𝗧 𝗩𝗶𝗿𝗮𝗹 𝗰𝗮𝘁𝗮𝗹𝗼𝗴𝘀📚: zenodo.org/records/1898...

Asier Fernández Pato@asierfdezpato.bsky.social · 5mo ago

🚨 𝗡𝗲𝘄 𝗽𝗿𝗲𝗽𝗿𝗶𝗻𝘁! After years of work, I'm excited share our manuscript "𝗣𝗿𝗲𝗴𝗻𝗮𝗻𝗰𝘆 𝗮𝗻𝗱 𝗘𝗮𝗿𝗹𝘆-𝗟𝗶𝗳𝗲 𝗚𝘂𝘁 𝗩𝗶𝗿𝗼𝗺𝗲 𝗶𝗻 𝘁𝗵𝗲 𝗟𝗶𝗳𝗲𝗹𝗶𝗻𝗲𝘀 𝗡𝗘𝗫𝗧 𝗰𝗼𝗵𝗼𝗿𝘁: 𝗢𝗿𝗶𝗴𝗶𝗻, 𝗣𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝗰𝗲, 𝗜𝗻𝗳𝗹𝘂𝗲𝗻𝗰𝗶𝗻𝗴 𝗙𝗮𝗰𝘁𝗼𝗿𝘀 𝗮𝗻𝗱 𝗛𝗲𝗮𝗹𝘁𝗵 𝗜𝗺𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀". doi.org/10.64898/202... A thread🧵👇 (1/11)

🚨 𝗡𝗲𝘄 𝗽𝗿𝗲𝗽𝗿𝗶𝗻𝘁! After years of work, I'm excited share our manuscript "𝗣𝗿𝗲𝗴𝗻𝗮𝗻𝗰𝘆 𝗮𝗻𝗱 𝗘𝗮𝗿𝗹𝘆-𝗟𝗶𝗳𝗲 𝗚𝘂𝘁 𝗩𝗶𝗿𝗼𝗺𝗲 𝗶𝗻 𝘁𝗵𝗲 𝗟𝗶𝗳𝗲𝗹𝗶𝗻𝗲𝘀 𝗡𝗘𝗫𝗧 𝗰𝗼𝗵𝗼𝗿𝘁: 𝗢𝗿𝗶𝗴𝗶𝗻, 𝗣𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝗰𝗲, 𝗜𝗻𝗳𝗹𝘂𝗲𝗻𝗰𝗶𝗻𝗴 𝗙𝗮𝗰𝘁𝗼𝗿𝘀 𝗮𝗻𝗱 𝗛𝗲𝗮𝗹𝘁𝗵 𝗜𝗺𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀". doi.org/10.64898/202... A thread🧵👇 (1/11)

Prophages of infant-derived Bifidobacterium longum subspecies employ antagonistic and synergistic strategies to persist in their host https://www.biorxiv.org/content/10.64898/2026.02.18.706556v1

Out now!!

Cell Reports@cp-cellreports.bsky.social · 12mo ago

Host and environmental determinants of human milk oligosaccharides and microbiota in the Lifelines NEXT cohort

New pre-print out \o/ All about CRISPR, metagenomes, and what you learn when you collect (a lot of) spacers from natural communities, with @apcamargo.bsky.social @urineri.bsky.social @lhug.bsky.social but also Uri Gophna, Nikhil George (not on Bsky I think) & others at JGI doi.org/10.1101/2025...

Early-life development of the gut virome and plasmidome: A longitudinal study in cesarean-born infants