In which @kevinbonham.com makes repeated and effusive plugs for @edyong209.bsky.social 's book "An Immense World" app.thestorygraph.com/books/5d4a4f...

An Immense World: How Animal Senses Reveal the Hidden Realms Around Us by Ed Yong

The Earth teems with sights and textures, sounds and vibrations, smells and tastes, electric and ...

app.thestorygraph.com

Kevin Bonham@kevinbonham.com · last mo.

A break from politics (mostly) to talk about magnetoreception in pigeons. In macrophages! Maybe... The latest @audiommunity.org 🧪

A break from politics (mostly) to talk about magnetoreception in pigeons. In macrophages! Maybe... The latest @audiommunity.org 🧪

Episode 57 - F'ing magnets, how do they work... in pigeons?

Insane Clown Posse aside, we know quite a lot about how magnets work. But how they work in animals to sense the earth's magnetic field -- less so.

open.substack.com

The goal isn't transparency, it's not even *really* about directing the science. It's about power. Go do whatever you can to push back! Don't know what you can do? @elizabethginexi.bsky.social has you covered: substack.com/@elizabethgi... 🧪 youtube.com/shorts/8P6rn...

The First Step Toward Authoritarian Control

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With links to @standupforscience.net 's guide to writing official comments to block the rule and lots of other resources

Kevin Bonham@kevinbonham.com · last mo.

If you aren't fired up and taking action on the new OMB rule change that would put science funding decisions in the hands of political hacks, get fired up. Lastest episode of @audiommunity.org, with links to resources for taking action in the post 🧪 audiommunity.substack.com/p/episode-56...

If you aren't fired up and taking action on the new OMB rule change that would put science funding decisions in the hands of political hacks, get fired up. Lastest episode of @audiommunity.org, with links to resources for taking action in the post 🧪 audiommunity.substack.com/p/episode-56...

Episode 56 - It's the institutions

We were going to talk about gut microbes and pregnancy immunology, but the power grab for government grant-making is taking our whole attention

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On the latest episode of @audiommunity.org , @woodrufflab.bsky.social and I talk through this wonderful new paper. A conceptually straightforward advance that massively expands the usefulness of this is kind of spatial 'omics 🧪

Episode 54 - Poop is lumen

New spatial 'omics technology that enables capturing *all* the RNA

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Yannis Ntekas@ntekasi.bsky.social · 5mo ago

Our work with Lena Takayasu and @dwmckellar.bsky.social in Iwijn De Vlaminck's lab is now out in @natmicrobiol.nature.com ! 🎉 Spatial transcriptomics maps host–gut microbiome biogeography at high resolution rdcu.be/e7i7o

20/25

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On the latest @audiommunity.org - No, we're probably not going to prevent all respiratory diseases with a chicken-egg vaccine, but it's still cool immunology! Plus, @woodrufflab.bsky.social and I kvetch about new NIH policies on peer review 🧪

Episode 53 - Something catastrophic

Can we use a single vaccine against chicken eggs to protect against literally every pathogen out there? Eh, probably not.

open.substack.com

🚨 Requesting help: I am looking for an agent who can facilitate more speaking gigs, podcast appearances, and interviews with journalists I want to more widely share my story and expertise as a trans geneticist who understands the reality and complexity of "biological sex" 🏳️‍⚧️🧬 Please signal boost?

Macrophages in your glands! Or are they dendritic cells? @woodrufflab.bsky.social and I discuss a new paper coining a new cell type - "adenophages" 🧪 open.substack.com/pub/audiommu...

Episode 52 - Close to the squeezey part

Glaaaands - In this episode, Matt and Kevin talk about a new paper describing a new kind of macrophage. Or is it a dendritic cell? Or are categories meaningless?

open.substack.com

Most of what the government invests in scientific research pays off - if not in nature papers, then in workforce training and education. Considering how small a percentage of the budget it is, it's a pretty remarkable return 🧪 youtube.com/shorts/q8nOE...

Funding science is a good investment

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In this episode, Matt and Kevin stick with the brain, this time looking at the immunological implications of a variant of a gene called APOE that has been linked to Alzheimer's. audiommunity.org/episodes/epi... It's a long one, and we get snarky in this one folks! Buckle up! 🧪🎤

Episode 50 - Kevin has learned a tautology

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This title isn't about the HHS secretary! This was an amazing conversation about Headbutting (it's related to #immunology, we swear) with @nicoleackermans.com 🧪, who just published a review describing the last 10,000 years of human thought on animals bashing skulls audiommunity.org/episodes/epi...

Episode 49 - Scratch that itchy worm in your head

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Assistant Professor position posted for my Department, Biological Sciences at UNC Charlotte! Current research foci: Immunology, Microbiology, Virology; Biomolecular Function; Proteostasis; Genome Integrity; Epigenome Regulation; Cancer; Environmental Risks. jobs.charlotte.edu/postings/65141

Excited to be talking to @nicoleackermans.com today about her work on headbutting in animals throughout the centuries! Do you have burning questions about neuroinflammation in bighorn sheep or the differences between woodpeckers and football players? Let us know! 🧪

In the latest episode, we're talking neonatal Tregs! What are they? Still don't know! What do they do? Still don't know! Where do they go? Ahh, the right question - it's the skin of course! With special guest @zackhilt.bsky.social 🧪 #immunology

Episode 48 - The tyranny f the FACS machine

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I recently recorded an Immunology Podcast called @audiommunity.org where I get to geek out on why Neonatal T cells are unique from Adult T cells. Please give them a listen and get the viewership up. Extra important to amplify the voice of real scientist and dampen all of the pseudoscience grifters.

The Tyranny of the FACS machine

In this episode Matt and Kevin welcome special guest Zach Hilt from the University of Toledo - we're talking neonatal Tregs!

audiommunity.org

In our latest episode, @woodrufflab.bsky.social and @kevinbonham.com talk about glycoRNAs, and the way they're shielded from the immune system in a new paper from the labs of @raflynn5.bsky.social and @vijayrathinam.bsky.social 🧪 audiommunity.org/episodes/epi...

Episode 47 - When you're a hammer

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Did you know that there are small RNAs embedded in the plasma membrane of your cells? I didn't! But your immune system sure does! New episode of @audiommunity.org out now! 🧪 audiommunity.org/episodes/epi...

Episode 47 - When you're a hammer

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The latest @audiommunity.org - Remembering David Baltimore by trying (and mostly failing) to explain the complex molecular biology in a classic #immunology paper describing the discovery of the VDJ recombinase gene 🧪 audiommunity.org/episode046

Episode 46 - Walk farther and farther to the left

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Oops! Forgot to post to Patreon for the last episode... #AI and #science - what's not to love? With @kevinbonham.com and @woodrufflab.bsky.social 🧪 Turns out, quite a lot www.patreon.com/posts/episod...

Episode 45 - Big if true | Audiommunity

Get more from Audiommunity on Patreon

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Episode 45 - Big if true audiommunity.org/episodes/epi... Someone made an AI-based "virtual lab" to engineer nanobodies - is this a paradigm shift in how we do science, or a transpararent and cynical effort to slurp up all of the citations for being first?

a little girl is making a funny face while sitting at a table with potted plants .

ALT: a little girl is making a funny face while sitting at a table with potted plants .

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@audiommunity.org · 12mo ago

In a couple of hours, @woodrufflab.bsky.social and @kevinbonham.com are going to discuss a new paper (in early preview) about an #LLM -based "virtual lab" that designed nanobodies for #sars-cov2 What would you want to know? Do you think this is a cool idea or harbinger of doom? 🧪

In a couple of hours, @woodrufflab.bsky.social and @kevinbonham.com are going to discuss a new paper (in early preview) about an #LLM -based "virtual lab" that designed nanobodies for #sars-cov2 What would you want to know? Do you think this is a cool idea or harbinger of doom? 🧪

1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said." It's literally a vital feature of both science and of representative democracy. I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.

RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’

HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.

scrippsnews.com

Bacteria have immune systems? And autoimmunity? Well... In this episode, Kate and @kevinbonham.com discuss a new paper showing that anti-phage defenses of bacteria can provide really broad protection, but pesky selection gets in the way 🦠 🧫 🧪 audiommunity.org/episodes/epi...

Evolution - it's a hell of a drug

Bacteria have immune systems? Even adaptive immune systems? And autoimmunity? Well... sort of

audiommunity.org

Everything you wanted to know about oxidized lipids & immunity, in one review. We explain how oxidized lipids impact inflammation, dendritic cells, anti-tumor immunity and more. Kudos to Joon Choi for his exceptional work. royalsocietypublishing.org/doi/10.1098/...

Oxidized phospholipid damage signals as modulators of immunity | Open Biology

Damage-associated molecular patterns (DAMPs) are self-derived molecules released during tissue damage that influence immune responses. Phospholipids, essential to cell membranes and lung surfactants, ...

royalsocietypublishing.org

Expression level of anti-phage defence systems controls a trade-off between protection range and autoimmunity By Nitzan Aframian and Avigdor Eldar. www.nature.com/articles/s41...

Expression level of anti-phage defence systems controls a trade-off between protection range and autoimmunity - Nature Microbiology

The authors examine several defense systems and find that increased expression enhances their protection range, albeit at a cost of autoimmunity.

nature.com

Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...

A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway

Key actors of mammalian immunity originated from bacterial antiphage systems. The full extent of immune system conservation between bacteria and eukaryotes is unknown. Here, we show that the silent in...

science.org

New bluesky account, revamped website, and a new episode to boot! @kevinbonham.com and @woodrufflab.bsky.social discuss a new paper about T cells in the subfornical organ... Why does that sound so unseemly? audiommunity.org/episodes/epi... youtu.be/st_g9eloJOw?...

Episode 43 - Why don't you go stain a brain?

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