'Half-moons' appearing in the shadows during the Solar eclipse in Straubing, Germany🌙 What a marvelous sight to witness this year! ☀️

PhD position in the Niederholtmeyer Lab (Straubing Germany) on feedback control of dynamic condensate assembly and disassembly edu.nl/7v364 Deadline: 26/04 @hniederho.bsky.social #SynCell #SyntheticCell

#Tardigrades are remarkable organisms! And we were intrigued by the possibility of borrowing their #desiccation-tolerance strategy for #cell-free systems🧪 We tested PrCAHS1 protein as potential protector against drying damage in #lysates. Our goal: make #CFES easier to store and access! Link below:

Why do intrinsically disordered proteins appear larger than they are in SDS-PAGE? We investigate how sequence properties affect SDS-PAGE mobility using synthetic IDRs. Conclusion: We need to consider both SDS binding and the compaction of protein-SDS complexes. www.biorxiv.org/content/10.6...

The latest QS World #UniversityRankings by Subject place us among the world’s top 20 universities in #engineering & technology, as well as #NaturalSciences: go.tum.de/261445 👏 #QSWUR 📷A.Heddergott

TUM among the top 20 in engineering and natural sciences

TUM has once again been ranked among the top 20 universities worldwide in the QS World University Rankings by Subject for engineering and natural sciences.

go.tum.de

Never underestimate the value of small discoveries and "happy accidents" in lab! For the Agar success in microbiology we should thank Fanny Angelina Hesse, the little-known hero with brilliant idea which changed the microbiology field forever ✨️

Javier Brumós@jbrumos.bsky.social · 5mo ago

One of the most important tools in modern Life Science research -the agar plate- actually started out as a secret ingredient for a summer dessert? 🍮🧪 Check what Fanny Angelina Hesse, the unknown hero of this story, did in Koch’s laboratory www.asimov.press/p/agar

New from us in @pnas.org : We considered the limits of condensate diversity, and engineered DNA droplets to form 9 distinct, homotypic, coexisting phases. Very hard to do this except with nucleic acids. Probably you can make more than 9. (1/3)

Scientists have seen Asgard archaea crawling for the first time. When it comes to the origin of eukaryotes, this is like seeing a feathered dinosaur in the wild. (Video courtesy of Philipp Ralder)

Roses are red Violets are blue If you fall in love with your hypothesis You’ll be biased to prove it true 🧪

I’m always happy to share my experience and discuss exciting scientific topics, especially #synbio and the construction of #syntheticcells 🧪🔬 Last week, I had lots of fun giving a lecture at the @tum.de Winter School for international students. Many thanks to the organisers for the kind invitation!

Feeling proud and inspired by all the amazing women I get to work with and learn from. Cheers to more discoveries, more voices, and more brilliance in every lab! 🔬✨ #WomenInSTEM #synbio #LifeSciences #Niederholtmeyerlab

Technische Universität München@tum.de · 6mo ago

Today is the #InternationalDayofWomenandGirlsinScience – highlighting equal opportunities, visibility, and #diversity in research and tech. Young women from our #community share their perspectives and visions for the future: go.tum.de/881869 #WomenInSTEM 📷A. Heddergott

What a pleasure it was to return to my Alma Mater, Vilnius University! I was invited to deliver a guest lecture for master’s students in the Systems Biology program at the Faculty of Medicine. We discussed SynBio topics, bottom-up Synthetic Cell research, and my own work on biomolecular condensates!

I am happy to share that our review on the Controlled Protein Synthesis in Microfluidic Environments has been published 🎉 www.sciencedirect.com/science/arti... Thanks to @emmacrean.bsky.social, Imre Banlaki, @jankalkowski.bsky.social, and @hniederho.bsky.social for great teamwork!

Can we build synthetic cells from de novo designed proteins? Find out more in the latest review @natrevbioeng.nature.com from Bela Frohn, Shunshi Kohyama and Petra Schwille. ❕Publication: doi.org/10.1038/s442... #ProteinDesign #SyntheticBiology @belafrohn.bsky.social ‬

I had the pleasure of giving a talk at the Biomolecular condensates conference in Copenhagen!☀️ Thanks to @proteinmagnus.bsky.social, @lindorfflarsen.bsky.social, and A.K. Buell for creating such an interesting program, and Fida Biosystems for the travel grant award! 👏 events.au.dk/biomolecular...

Very exciting program for the next 3 days! Will talk about microfluidic platform for biomolecular condensates on the second day. See you there!

Magnus Kjærgaard@proteinmagnus.bsky.social · last yr.

Trigger warning: FOMO How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀 "Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!

I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...

Most bacterial gene families are biased toward specific chromosomal positions

The arrangement of genes along bacterial chromosomes influences their expression through growth rate–dependent gene copy number changes during DNA replication. Although translation- and transcription-...

science.org

We are looking forward to the workshop "Biomolecular Condensates and Polymer Phase Transitions" which we are organizing together with the IPF Dresden (dpd.ipfdd.de). It will be held from May 25th - 28th, 2025 in Meißen, near Dresden. The registration deadline is May 5th, 2025.

Component library creation and pixel array generation with micromilled droplet microfluidics www.nature.com/articles/s41...

Component library creation and pixel array generation with micromilled droplet microfluidics - Microsystems & Nanoengineering

Microsystems & Nanoengineering - Component library creation and pixel array generation with micromilled droplet microfluidics

nature.com

Calling all structural enthusiasts! An accurate depiction of the structure of DNA in #Lego is under 2000 supporters away from being considered to become a real set! It even has Franklin, Watson, and Crick minifigures and a Lego photgraph 51 and Bragg's law! ideas.lego.com/projects/c92...

Lego DNA 2.0: Double Helix History

Step into the extraordinary world of Lego DNA 2.0: Double Helix History, a celebration of the 70th anniversary of the landmark DNA structure ...

ideas.lego.com

Latest #CDlab paper by Nicola De Franceschi ea now in eLife @elife.bsky.social: 'Interaction hierarchy among Cdv proteins drives recruitment to membrane necks', an in vitro study of the fascinating and unique proteins machinery that drives cell division in archaea elifesciences.org/reviewed-pre...

New review / perspective with @albertilab-tud.bsky.social on our thoughts on condensate speciality and recruitment, focusing on interplay between site specific and chemically specific interactions www.cell.com/molecular-ce...

Molecular determinants of condensate composition

Biomolecular condensates are non-stochiometric assemblies that organize cellular matter in space and time. Despite much work, many questions remain regarding what determines the recruitment and exclus...

cell.com

1/ 🚨We’re thrilled to share our latest study: "Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure" 🌟 www.biorxiv.org/content/10.1... How do biomolecular condensates achieve their cellular roles? It comes down to their internal structure. 🧵⬇️

Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure

Biomolecular condensates play key roles in the spatiotemporal regulation of cellular processes. Yet, the relationship between atomic features and condensate function remains poorly understood. We stud...

biorxiv.org