We're hiring! If you are interested in working with us, please apply until July 15th.

We had a great day at our lab outing yesterday at Saxon Switzerland!

Congratulations to Prof. Simon Alberti @albertilab-tud.bsky.social for being elected to German National Academy of Sciences Leopoldina @leopoldina.org! 🥳 Read more ➡️ tud.link/bc82ng #CMCBnews @tudresden.bsky.social

“Super macrophages” against cancer 🧬 Prof. Michael Sieweke, Dr. Anke Fuchs, and Dr. Angela Jacobi are developing a new immune cell therapy targeting solid tumors. Backed by €2.5M from the EIC, StemPhage aims to bring this approach closer to clinical use 🔬 Read more ➡️ tud.link/vwwmxg #CMCBnews

I'm very excited to announce the funding of a new DFG research unit FOR 5872 "Chaperone-mediated regulation of the emergence of disease-causing amyloids inside biomolecular condensates" that I lead together with Simon Alberti. More information can be found here: www.leibniz-fli.de/news-events/...

Chaperones in focus: FLI heads new DFG research group on protein folding

The German Research Foundation (DFG) is funding seven new research groups (FOR) with a total of €33 million. One of these, DFG-FOR 5872, is dedicated to the role of molecular chaperones in the regulat...

leibniz-fli.de

How does protein folding change inside biomolecular condensates? Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social

Nate@nathanieldhess.bsky.social · 7mo ago

I am very excited to share our pre-print that was just released on the bioRxiv entitled "Biomolecular Condensates Dictate the Folding Landscape of Proteins" doi.org/10.64898/202... Very grateful for @jerelleaj.bsky.social and the members of the Joseph Group for their support on this project! (1/4)

We are thrilled to announce that our Postdoc Nagaraja Chappidi is starting his own research group at @mpi-cbg.de ! www.mpi-cbg.de/research/res...

Group Leader

mpi-cbg.de

++++ We are hiring ++++ The DFG-funded Research Training Group RTG 3120 – Biomolecular Condensates: From Physics to biological Functions” in Dresden is currently recruiting PhD-candidates. More Info here: dresdencondensates.org/join-us/ Please apply until October 31,2025

Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!

A label-free method for measuring the composition of multicomponent biomolecular condensates - Nature Chemistry

Biomolecular condensates are made of multiple components but current techniques cannot capture their complex composition quantitatively. Now it has been shown that the dense-phase binodal point defini...

nature.com

Physics of Life Dresden@poldresden.bsky.social · 11mo ago

New findings out today in Nature Chemistry from the Brugués @brugueslab.bsky.social at PoL, alongside colleagues at @mpi-cbg.de and the IPF Dresden 🧪 The authors have discovered a new method to identify the molecular makeup of biomolecular condensates Read our press release here: tud.link/ajwtaz

Congratulations to Kai Simons, one of our founding directors, for receiving the Cothenius-Medal of the German National Academy of Sciences Leopoldina @leopoldina.org for his insights into the function of cell membranes. 🎉 www.mpi-cbg.de/news-outreac...

Nationale Akademie der Wissenschaften Leopoldina@leopoldina.org · 11mo ago

Für sein herausragendes wissenschaftliches Lebenswerk wird Leopoldina-Mitglied Kai Simons, Direktor emeritus am Max-Planck-Institut für molekulare Zellbiologie und Genetik in Dresden @mpi-cbg.de, mit der Cothenius-Medaille geehrt. ➡️ www.leopoldina.org/presse-1/nac...

🔬 #BSc or #MSc and research? Come to @tudresden.bsky.social & the CMCB! Meet our iGEM team, supervised by @albertilab-tud.bsky.social and the Honigmann lab, ready for the @igemhq.bsky.social competition. Video with EN subtitles ➡️ youtu.be/MMffDJyjeGg #StudyinGermany #LifeSciences

Student Research at TU Dresden – Celina and Malte present their iGEM project | STUDY IN SAXONY

YouTube video by STUDY IN SAXONY

youtu.be

TU Dresden@tudresden.bsky.social · last yr.

Forschen im #Studium: Celina & Malte studieren an der Fakultät Biologie & dem @cmcb-tud.bsky.social. 🧬 Sie sind Teil des diesjährigen iGEM-Teams TRAPS. iGEM ist der bedeutendste Studierendenwettbewerb im Bereich der Synthetischen #Biologie. "Study in Saxony" stellt sie vor. 🎥 youtu.be/IIG_4ti5anw

Great trip to Prague with (part of) the team in perfect weather conditions.

Lively poster session after a day full of talks (😅) by @drummondlab.bsky.social, Allie Obermeyer, @albertilab-tud.bsky.social, Sam Safran, and @tanjamittag.bsky.social at the #KITP biomol25 conference on biomolecular condensates. Great conversations between theorists and experimentalists!

A team @mpi-cbg.de from @hymanlab.bsky.social & the @edinburghup.bsky.social (Richard Wheeler group) has identified the molecule lipoamide that can prevent the formation of pathological stress granules - protein-rich condensates associated with cellular stress and ALS. www.mpi-cbg.de/news-outreac...

Molecule Disarms Cellular Stress Granules Linked to ALS

Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.

mpi-cbg.de

Collaboration with the Alberti lab @albertilab-tud.bsky.social here in Dresden @biotec-tud.bsky.social and Jeetain Mittal group in Texas jeetain.wixsite.com/mittal-lab @rnadavid.bsky.social @pombo-garcialab.bsky.social

Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century. ℹ️ tu-dresden.de/tu-dresden/n...

Trigger warning: FOMO How often do you go to a conference where you are excited about EVERY SINGLE TALK! Well, I guess it helps if you get to make the program. 😀 "Biomolecular condensates: From fundamental principles to applications in health and biotech" kicking off at 9 AM!

Das Leben erkennen: 🔬 Wie lassen sich Begegnungen von Molekülen sichtbar machen & was bedeutet das für die Entwicklung neuer Medikamente? Prof. Ulrich Rant stellt sich & seinen Forschungsschwerpunkt am 15.5. in der Universitätsweiten Antrittsvorlesung vor. ℹ️ tu-dresden.de/tu-dresden/n...

TU Dresden@tudresden.bsky.social · last yr.

Sensing life's interactions: 🔬 Prof. Ulrich Rant develops biosensoring technologies that can make the invisible bonds & dissolutions between single molecules visible. This can deepen our understanding of how they act in complex biological environments like cancer cells. 🎥 youtu.be/Tht3IDQgn9k

Check out this interesting article about #biomolecular #condensates (in German): Lebenswichtige Molekülklumpen www.spektrum.de/news/lebensw... #hymanlab.bsky.social #@rohitpappu68.bsky.social

Zellbiologie: Lebenswichtige Molekülklumpen

»Biomolekulare Kondensate« in unseren Körperzellen organisieren die dortigen Abläufe und bieten neue Ansatzpunkte, um Krankheiten zu behandeln

spektrum.de

This summer in beautiful Santa Barbara we will run a 3-day conference on “Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” June 16 to 18th. Register now: www.kitp.ucsb.edu/activities/b...

All atom simulations of peptides were used to investigate differences in pair interactions in dilute vs. dense phase mimics of condensates. Backbone-mediated interactions were found to weaken pairwise associations in dense phases giving rise to percolated networks. doi.org/10.1038/s420...

Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates - Communications Chemistry

Biomolecular condensates formed by intrinsically disordered protein condensates are known to be semidilute solutions, however, the molecular interactions in the dilute versus dense phases remain under...

doi.org

Welcome to our new Master students Samyuktha, Louis and Georg! We wish you great success with your projects!. It's wonderful to have you in the lab! photos by Magdalena Gonciarz

Applications for our international and interdisciplinary Master's Programs are now open! The applications start on April 1 and run until May 31, 2025. For detailed information please visit our website tu-dresden.de/cmcb/die-ein...

The @tothpetroczylab.bsky.social together with the @albertilab-tud.bsky.social developed SHARK-capture to detect recurring patterns (motifs) in intrinsically disordered protein regions (IDRs). Publication in Protein Science. www.mpi-cbg.de/news-outreac...

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes! Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner. @abelljonny.bsky.social, @michael-e-ward.bsky.social, et al. www.nature.com/articles/s41...

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes - Nature Communications

Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...

nature.com

Cell published a “Cell Line: 2014–2024,” which is a timeline highlighting a set of exceptional scientific works published in @cellpress.bsky.social. The timeline features a publication from the @hymanlab.bsky.social & @albertilab-tud.bsky.social from 2015. www.cell.com/cell/pdf/S00...

Just finished this review by @alexholehouse.bsky.social & @albertilab-tud.bsky.social. Balanced, careful about overstatements or ambiguities, but also bold in making proposals as to how these things called condensates work, or how me might understand them, in an approximated but useful way, to work.

Molecular determinants of condensate composition

Cells use membraneless compartments to organize their interiors, and recent research has begun to uncover the molecular principles underlying their as…

sciencedirect.com

We are looking forward to the workshop "Biomolecular Condensates and Polymer Phase Transitions" which we are organizing together with the IPF Dresden (dpd.ipfdd.de). It will be held from May 25th - 28th, 2025 in Meißen, near Dresden. The registration deadline is May 5th, 2025.

In the cover story of the February issue of @sciam.bsky.social I explain what biomolecular condensates are and why they are transforming cell biology. A short 🧵 (You'll need a subscription to read the article.) www.scientificamerican.com/article/myst...

Mysterious Blobs in Cells Are Changing the Way We Understand Life

Tiny specks called biomolecular condensates are leading to a new understanding of the cell

scientificamerican.com

🎉 Our Master’s programs are accredited until 2032! 🧬 Regenerative Biology and Medicine 🔬 Molecular Bioengineering 🌌 Physics of Life ✅ The programs went through internal quality check at TU Dresden and passed with flying colors! Applications open April 1! More info ➡️ tud.link/ynf76g #Masters #MSc