📢 I’m recruiting a postdoc at KTH to work on virome-wide serology in the context of pandemic preparedness! The project will study antiviral immunity in the Swedish population using novel serological methods and blood self-sampling. Please share! Apply: www.kth.se/lediga-jobb/...

In exploratory omics studies in humans, it is quite common to evaluate the prediction accuracy of demographic variables like age and sex using the omics variables. In what situation would you actually need to do this? Isn't there some more natural statistical framework that makes more sense? 1/2

75% is insane. Government loans for scientific funding would be a crazy good investment for countries that can afford it.

Nature@nature.com · 2y ago

The massive changes in US research brought about by the new administration of President Donald Trump are causing many scientists in the country to rethink their lives and careers https://go.nature.com/41OhAgK

13 chair positions open @inserm.fr to lead a junior research group in France covering #neuroscience, #immunology, #bioinformatics, #bioengineering, #biotherapy, #public health pro.inserm.fr/rubriques/co... 🧪🔬

ahhhhhhhhhh

The best thing Americans can do right now is minimizing domestic spending and donating to Ukraine: u24.gov.ua Europeans should also donate more, stop buying american, invest in EU defense stocks, and pressure their governments to donate more and ramp up defense spending.

Complete batshit lunacy on the president's Truth Social account. Yes, he really posted this.

Today, the US stood with Russia and North Korea — and against our allies — in voting against a UN resolution to condemn Russia's aggression against Ukraine. Let that sink in. This is a betrayal of the Ukrainian people, our allies, our interests and those who aspire for freedom.

Elon Musk literally just verified the account 'Adolf Hitler' as an official government account on his website. It is time for EU to block it, just like they blocked the website of the russian state-sponsored media channel RT. It is the source of so much misinformation.

Elon Musk literally just verified the account 'Adolf Hitler' as an official government account on his website. It is time for EU to block it, just like they blocked the website of the russian state-sponsored media channel RT. It is the source of so much misinformation.

www.reddit.com/r/law/commen... US going full dictatorship quickly.

From the law community on Reddit: The full Executive Order is out! ⚠️ This is the biggest executive power grab in U.S. history. ⚠️

Explore this post and more from the law community

reddit.com

This rate of validation suggests that antibodies should be considered non-specific until proven otherwise: 357 validated out of 1,124 tested. .

Here's our latest work on proteome profiling of self-sampled dried blood spots to gain insights into the heterogeneity of the immune response against infections and vaccinations. We enrolled random citizens by postal mail to learn more about the molecular effects beyond those seeking medical care.

medRxivpreprint@medrxivpreprint.bsky.social · 2y ago

Multi-molecular phenotyping in a self-sampling population https://www.medrxiv.org/content/10.1101/2025.01.14.25320405v1

🩸🔬 Introducing #CryoSCAPE, a groundbreaking technique that keeps blood cells alive in deep freeze. This innovation promises to expand the reach of cutting-edge single-cell technologies to rural or underserved populations. ✨ 🧵 #SingleCellTech #RNAseq

‼️‼️ Last few days to apply to join us as a #PostDoc in #SystemsImmunology and explore mechanisms of #SexDifferences in #Human #Immunity at Lund University in #Sweden More info on how to apply below (please RT)

Camila Consiglio@consigliocr.bsky.social · 2y ago

Join our #SystemsImmunology Lab (Lund University, Sweden) as a #Postdoctoral Fellow! 🔬 Project: To investigate sex hormone regulation of human immune function using CRISPR, transcriptomics, and immunophenotyping. Fully funded 2-year position (more info attached). 🗓️ Apply by Jan 6, 2025

Trump just casually hinting that territories of allied countries might have to be incorporated into the United States because of 'national security'.

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8

High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics

The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...

bmcgenomics.biomedcentral.com

I demand that every study that uses fecal samples be renamed from a "gut microbiome" to "fecal microbiome" study, including in the title. Thus, researchers would have to focus on good study design rather than sensationalism. Stool samples are NOT representative for the gut.

I am excited about Pixelgen Technologies molecular pixelation assay for single cell spatial proteomics. They have a new new tech note out in collab with #illumina www.illumina.com/content/dam/...

These types of solutions look very interesting for scientific publishing: curvenote.com Producing manuscripts (especially figures) suck due to the poor software available. Reading is an equally terrible experience, having to zoom in on figures and scroll up and down to look at references.

Curvenote | Scientific publishing infrastructure

Curvenote develops next-generation publishing infrastructure and writing tools to support open, reproducible research. A beautiful writing tool designed for technical writing, connected to Jupyter. Wr...

curvenote.com

I created a starter pack for systems immunology - let me know if you would like to be added. Excited to be here on @bsky.app go.bsky.app/PjH2Fuj

Does anyone have experience in using AI tools dedicated to the research grant writing process and found them useful? I've found a few, but they still seem a bit too general and rudimentary.

Fresh from #bioRxiv: Longitudinal blood #microsampling and proteome monitoring facilitate timely intervention in experimental type 1 diabetes. #Proteome #Diabetes #Prevention #teamscience @scilifelab.bsky.social #KarolinskaInstitutet #KTH #TUM www.biorxiv.org/content/10.1...

Longitudinal blood microsampling and proteome monitoring facilitate timely intervention in experimental type 1 diabetes

Symptoms of immune-mediated diseases (IMIDs) typically appear after irreversible tissue damage, making early interventions based on pre-symptomatic indicators crucial. Current efforts to identify mole...

biorxiv.org

Data on the effects of preanalytical factors on single-cell omics are severely lacking (as indicated by the lack of refs in this paper). It is great that this is being investigated for ATACseq and that methods to mitigate it are developed.

bioRxiv Genomics@biorxiv-genomic.bsky.social · 2y ago

Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis https://www.biorxiv.org/content/10.1101/2024.11.20.624480v1

I've seen a range of medicine and biomedicine-related starter packs, but has anyone seen some that are more medtech- or medical engineering-related?

As someone who has worked extensively with antibodies, I agree these initiatives are crucial. It's scary to imagine that we might only see the tip of the iceberg. Studying the effects of fluorescent tagging and tissue fixation on antibody binding would also be very interesting.

Johan Duchêne@johanduchene.bsky.social · 2y ago

"The antibodies don’t work!" We, like many labs, have faced issues with bad antibodies cell.com/cell-stem-ce... Great to see that some are tackling this problem head-on! Read more about their solutions: www.nature.com/articles/d41... #ImmunoSky #Metaresearch #Openscience

Introductory post! I'm an immunologist who recently transitioned into developing engineering solutions for clinical microsampling. My main interests are population studies in human systems immunology and ways to simplify them. If this interests you, give me a follow or send me a message!