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AJ Simon

@ayejaysimon.bsky.social

Neuroscience PhD candidate at Yale Brain networks, cognition, psychiatry Constable Lab NSF GRFP fellow @Neuroscapeucsf alum Twitter: @ayejaysimon

20 Posts193 Follower286 Folgt
Biological Psychiatry@biologicalpsych.bsky.social · 5mo ago

Running therapy is linked to the reorganization of large-scale brain dynamics in individuals with affective disorders, and this reorganization is linked to symptom improvement.

Running therapy reorganizes dynamic brain networks linked to symptom improvement in affective disorders

Exercise therapy reduces depressive and anxiety symptoms, but its neural mechanisms remain unclear. We examined whether running therapy reorganizes dynamic brain functional connectivity in affective…

biologicalpsychiatrycnni.org

AJ Simon@ayejaysimon.bsky.social · 5mo ago

Thoroughly enjoyed participating in the French-American doctoral exchange program in precision psychiatry hosted by the INSERM a couple weeks ago. Looking forward to staying in touch with everyone I met and forming new collaborations

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Russ Poldrack@russpoldrack.org · 7mo ago

"AI amplifies whatever is already there. Good discipline becomes great output. No discipline becomes technical debt at machine speed. Anthropic chose a direction. Go faster. Have Claude check Claude. And when it breaks, go faster still." substack.com/home/post/p-...

Claude Code's Source: 3,167-Line Function, Regex Sentiment

Anthropic claimed 100% of Claude Code is AI-written. A source leak exposed a 3,167-line function, regex sentiment analysis, and 250K wasted API calls daily

substack.com

Todd Constable@toddc.bsky.social · 8mo ago

It's important to note that when discussing brain structure-function relationships across scales, that the definition of function changes with scale. Keep it straight! @sbe.bsky.social link.springer.com/article/10.1...

Anatomic & functional brain atlases: connecting functional flexibility with fixed infrastructure - Brain Structure and Function

Brain Structure and Function - Recent advancements in imaging across scales has propelled the development of anatomic brain atlases reflecting a wide range of cellular properties. It’s...

link.springer.com

Todd Constable@toddc.bsky.social · 9mo ago

I wrote an perspectives piece relevant to the structural atlasing endeavors. Structural atlases are not the end of the story. This perspective calls for models that take into account the flexible functional organization within this fixed architecture. www.frontiersin.org/journals/neu...

Frontiers | Structure–function relationships across scales: implications for atlases

Neuroscience aims to understand how the structural and functional organization of the brain relates to behavior. Structural studies at the cellular level est...

frontiersin.org

Alessandro Gozzi@gozziale.bsky.social · 11mo ago

As we chase whole-brain signatures of cognition with fMRI, this fascinating perspective argues that cognitive signals are broadly distributed...but far from everywhere! For those of us using whole-brain neuroimaging lots to think about.. 👇 www.nature.com/articles/s41...

How distributed is the brain-wide network that is recruited for cognition? - Nature Reviews Neuroscience

Both localized and distributed views on the functional organization of the brain have been put forward. In this Perspective, Rosen and Freedman examine the degree to which these two views account for ...

nature.com

AJ Simon@ayejaysimon.bsky.social · 11mo ago

Congrats on getting this published in Biomedical Signal Processing and Control @tifenpan.bsky.social! Here, we showed that signals from frontal EEG channels predicted emotional states while listening to music, but other channels and peripheral physiological sensors did not improve model performance.

When more is not better: Predicting human emotional states with brain and bodily biosensors

Recent technological advances have made wearable biosensors increasingly accessible, affordable, and sensitive, driving their widespread adoption for …

sciencedirect.com

AJ Simon@ayejaysimon.bsky.social · 11mo ago

Excited to see this paper out in Biological Psychiatry! It highlights that emotional pain and fear represent distinct PTSD dimensions, leading us closer to identifying PTSD subtypes with dissociable biological underpinnings. Congrats on leading the charge on this cool study @zivbenzion.bsky.social

Dissecting Fear and Emotional Pain in PTSD: From Symptom Networks to Neural Signatures

Posttraumatic stress disorder (PTSD) is a heterogeneous condition with diverse symptom presentations and emotional experiences. While fear is traditio…

sciencedirect.com

Jordyn R. Ricard@jordynricard.bsky.social · last yr.

Excited to share our new preprint! We conducted a spatial meta-analysis of community violence and mental health, synthesizing 155 articles (k = 769) to test how exposure to community violence is associated with mental health problems, and how state social service investments moderate the link. 💵

PsyArXivBot@psyarxivbot.bsky.social · last yr.

The role of state social service spending in moderating mental health outcomes of community violence: a spatial meta-analysis: https://doi.org/10.31234/osf.io/zr94j_v1

Caterina Gratton@caterinagratton.bsky.social · last yr.

Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization? @rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print): go.illinois.edu/Gratton2025-... #neuroskyence #psychscisky #MedSky 🧵👇

Dense Phenotyping of Human Brain Network Organization Using Precision fMRI

The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...

go.illinois.edu

AJ Simon@ayejaysimon.bsky.social · last yr.

Couldn’t agree more. It’s easy to blame the “other” side for not trusting scientists, but to begin to repair these fractures it’s our responsibility to step up and be leaders and engage with the community

Nicole Rust@nicolecrust.bsky.social · last yr.

A thought-provoking piece in Nature Neuroscience by many neuroscience colleagues: "Science must break its silence to rebuild public trust". Lots to think about here. www.nature.com/articles/s41...

Public engagement: building common ground How can we help to bridge this divide? Simply producing more excep­ tional science will not be enough to rebuild public trust. Rather, we must adopt a new model that recognizes communication and advocacy as core pillars of science, on a par with rigor and reproducibility. Public engagement efforts should be valued for faculty promotions, much like obtaining grants and publishing our findings in scientific journals. Researchers should be recognized and rewarded for activities such as giving public talks, working with local schools, engaging with policy­ makers, developing social media campaigns and platforms or writing accessible articles for general audiences. Developing these skills must be an integral part of scientific training, reinforcing the notion that the responsibility to champion science lies with us. Courses that teach graduate students and postdocs to communicate complex ideas clearly, to use social media effectively and to advocate for evidence­based policies must be deemed critical and supported by our universities. These efforts should not be viewed as distractions from research but woven into the fabric of what we do as scientists. Rebuilding public trust requires a cultural paradigm shift: scientists must see themselves not just as producers of knowledge, but also as its ambassadors and translators. Such a fundamental change will occur only if it is embraced by our scientific leaders and institutions, emphasizing the critical role of public engagement for science to succeed.