Thank you @mucosalimmunol.bsky.social for allowing me to discuss some aspects for how immunity may work differently in babies and with Petter Brodin, a thought leader in this important area

Mucosal Immunology@mucosalimmunol.bsky.social · 3w ago

It’s #MucosalMonday and time for another MI Podcast episode, fresh from #ICMI2026. Hear from the poster sessions, and listen to Sing Sing Way @babiesresearch.bsky.social and Petter Brodin discuss the immune system during infancy. www.iheart.com/podcast/269-...

#ICMI2026 Reviews from the speakers! Sing Sing Way @babiesresearch.bsky.social discusses “Learning immunology from mothers and babies“. Catch his talk on Thursday and read his review: www.mucosalimmunology.org/article/S193...

Learning immunology from mothers and babies from @babiesresearch.bsky.social: www.mucosalimmunology.org/article/S193...

@Model.ShareSubject www.marchofdimes.org/our-work/res... Our pilot data giving women at high risk for pregnancy complications free mouthwash shows some amazing protective effects! Thank you @marchofdimes.org @proctorgamble.bsky.social

Mouthwash Use in Pregnancy Linked to Better Outcomes

March of Dimes scientists have findings linking mouthwash use in pregnancy to a reduction in preeclampsia, preterm birth, and more.

marchofdimes.org

Learning immunology from mothers and babies www.sciencedirect.com/science/arti... The maternal-fetal dyad can reveal strategies for improving pregnancy outcomes, but also how immunology works applicable to many other physiological contexts @mucosalimmunol.bsky.social @societymucosalimm.bsky.social

Learning immunology from mothers and babies

Pregnancy is an immunological marvel allowing intimate approximation between genetically discordant tissues of maternal and fetal origin. Shared immun…

sciencedirect.com

Protective maternal gut instincts www.nature.com/articles/d41... So thankful to @nature.com for the opportunity to highlight another exciting example of immunology learned from mothers, “protective maternal gut instincts” by @aiinglim.bsky.social @princetonmolbio.bsky.social

Protective maternal gut instincts

Pregnancy poses many challenges, including protecting against infection and increased nutritional demands. Pregnancy-associated gut changes offer some help.

nature.com

Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity - Mucosal Immunology www.mucosalimmunology.org/article/S193...

Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity

Although pathobiont microbes capable of causing systemic infection ubiquitously colonize mucosal tissues, invasive infection only occurs infrequently. This reflects increasingly recognized protective ...

mucosalimmunology.org

Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity - Mucosal Immunology www.mucosalimmunology.org/article/S193... part of the lab investigates commensal fungi as another example of expanded tolerance, but have instead found immunogenicity

Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity

Although pathobiont microbes capable of causing systemic infection ubiquitously colonize mucosal tissues, invasive infection only occurs infrequently. This reflects increasingly recognized protective ...

mucosalimmunology.org

Back story (link.growkudos.com/1pt9jbrx24g) behind our recent publication... Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance | PNAS www.pnas.org/doi/10.1073/...

Tolerance to intestinal microbes and the developing fetus share similar immunological mechanisms

Pregnancy is remarkable in that mothers tolerate the developing fetus expressing immunologically foreign paternal antigens. These foreign antigens stimulate rejection in other contexts, such as organ ...

link.growkudos.com

Thanks for highlighting our work with the other outstanding recent discoveries

Immunology Podcast@immunologypodcast.com · 5mo ago

In our latest episode, we discuss new work from the lab of Dr. Sing Sing Way at Cincinnati Children’s Hospital. It shows that newborns with E. coli #sepsis lack protective maternal antibodies, and maternal priming can provide protection. 1️⃣ https://go.nature.com/40rtn2U 2️⃣ https://bit.ly/4sYIflI

Mama's T cells also need KLF2 for promoting fertility and optimal pregnancy outcomes. Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance | PNAS www.pnas.org/doi/10.1073/...

Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance | PNAS

Pregnancy requires expanded maternal tolerance to semiallogeneic fetal-expressed antigens to protect against fetal loss and other pregnancy complic...

pnas.org

I keep learning new ways maternal antibodies protect infants! The latest from @babiesresearch.bsky.social on protection against E. coli sepsis and new potential vaccine targets.

Sing Sing Way@babiesresearch.bsky.social · 5mo ago

Another twist to why newborn babies more vulnerable to infection. Beyond immune cell immaturity, layering, active suppression... maternal pathogen-targeted antibodies still protect. Grateful @Nature sharing this hopefully uplifting glass half (99.9%)-full perspective www.nature.com/articles/s41...

So nice to see a whole issue of @cp-trendsimmuno.bsky.social dedicated to the topic of perinatal and early life immunity, especially the great contribution by new people bringing new perspectives to this important but still grossly understudied developmental window

Cell Press@cellpress.bsky.social · 5mo ago

Special Issue from @cp-trendsimmuno.bsky.social: Perinatal and early life immunity. Explore the full issue: www.cell.com/issue/S1471-...

Thank you @lizszabo.bsky.social for this beautiful summary

Liz Szabo@lizszabo.bsky.social · 5mo ago

I never get tired of writing about moms and babies. This was a fun topic to research. Newborns protected from E coli infections by microbes from mom, study from @babiesresearch.bsky.social suggests. www.cidrap.umn.edu/e-coli/newbo...

Dr. Sing Sing Way joined Cincinnati Public Radio's Cincinnati Edition to discuss his new study on how maternal antibodies protect newborns — and what this could mean for preventing serious infections. 🎧Listen here, or wherever you get your podcasts: https://ow.ly/AWbK50YwOP0

New research looks at mother's antibodies that protect babies from E. coli

Cincinnati Children's study reveals that many newborns are protected from serious bacterial infections by antibodies passed from mother before birth.

ow.ly

Thank you for this nice summary

Early-life Immune Network Europe@efis-eline.bsky.social · 5mo ago

Nearly every baby is colonized by various E. coli at birth, but luckily only 1 in 1000 develops a severe infection: A new paper in Nature shows how maternal IgG specific to mum`s gut E.coli protects neonates. Read here: www.nature.com/articles/s41... #EFIS #ELINE #NeonatalImmmunology (1/7)

Thank you Vipul and Stephanie for this lovely invitation, to share so many immunological secrets we can learn from studying mothers and babies. You are building a great program there at @immunology-nu.bsky.social and I am honored to spend the day learning from you all

Center for Human Immunobiology@immunology-nu.bsky.social · 5mo ago

Dr. SingSing Way joined CHI last week to speak on "Learning immunology from mothers and babies". @babiesresearch.bsky.social

New research led by our experts finds newborns who develop severe E. coli infection have lower levels of protective antibodies from their mothers. The study, published in Nature, could help identify high-risk infants and guide new prevention strategies. Learn more and see what's next:

Mothers’ Exposure to Microbes Protect their Newborn Babies Against Infection - Research Horizons

scienceblog.cincinnatichildrens.org

Natural maternal immunity protects neonates from Escherichia coli sepsis @cincyresearch.bsky.social @babiesresearch.bsky.social @nature.com www.nature.com/articles/s41...

Another twist to why newborn babies more vulnerable to infection. Beyond immune cell immaturity, layering, active suppression... maternal pathogen-targeted antibodies still protect. Grateful @Nature sharing this hopefully uplifting glass half (99.9%)-full perspective www.nature.com/articles/s41...

Natural maternal immunity protects neonates from Escherichia coli sepsis - Nature

Neonatal sepsis caused by Escherichia coli is associated with reduced transfer of pathogen-specific maternal antibodies and, in a mouse model, can be prevented by maternal preconceptual&nbsp...

nature.com

Thrilled for my colleagues in the CIT (www.cincinnatichildrens.org/research/div...) on their Research Team Award from @cincyresearch.bsky.social! @alenghatlab.bsky.social @babiesresearch.bsky.social @ttilburgs.bsky.social

New tools for studying the “hidden guests” within us www.lifescienceeditors.com/2026/01/19/n... thank you for highlighting our work, and more importantly this remarkable area of science

New tools for studying the “hidden guests” within us - Scientific editing and writing experts - Life Science Editors

Scientific editing and writing experts for manuscripts and grants

lifescienceeditors.com

@nature.com book review by @babiesresearch.bsky.social on book Hidden Guests Some of your cells are not genetically yours — what can they tell us about life and death? nature.com/articles/d41... greystonebooks.com/products/hid...

Some of your cells are not genetically yours — what can they tell us about life and death?

A tiny population of cells that are passed across the placenta between mother and baby challenge basic tenets of human immunology.

nature.com

Some of your cells are not genetically yours — what can they tell us about life and death? www.nature.com/articles/d41... Thank you Lise Barneoud for this beautiful piece, and @Nature for highlighting microchimerism to the broader community. Happy 2026 everyone with hidden cellular guest!

Some of your cells are not genetically yours — what can they tell us about life and death?

A tiny population of cells that are passed across the placenta between mother and baby challenge basic tenets of human immunology.

nature.com

Congrats to Dr. Sing Sing Way on being elected to @nam.edu —one of the highest honors in health & science. His pioneering research on pregnancy & early-life immunity is transforming how we understand & protect maternal & infant health. Read more: scienceblog.cincinnatichildrens.org/sing-sing-wa...

Sing Sing Way Elected to National Academy of Medicine - Research Horizons

The National Academy of Medicine has elected Sing Sing Way, MD, PhD, a member, one of the highest honors in health, medicine and science.

scienceblog.cincinnatichildrens.org

National Academy of Medicine@nam.edu · 10mo ago

Congratulations and welcome to the 100 new members elected today to the National Academy of Medicine! #NAMmtg nam.edu/news-and-ins...

Congrats to Dr. Sing Sing Way @babiesresearch.bsky.social and team at the Center for Inflammation and Tolerance @cincychildrens.bsky.social for shedding fresh light on how #microchimerism works. Read more on our science blog: scienceblog.cincinnatichildrens.org/deeper-micro...

Immunity@cp-immunity.bsky.social · 11mo ago