Transient inhibition of type I interferon enhances CD8⁺ T cell stemness and #vaccine protection. From Benjamin Broomfield @benjbroom.bsky.social, Joanna Groom @groomlab.bsky.social and colleagues 👉 rupress.org/jem/article/... 📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...

Hey "Friends" The 2025 edition of our #AwkwardLabPhoto celebrates an incredible year of growth, publications, promotions, PhD submissions and grads I feel immensely proud and grateful to be part of this team

The 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 highlights research in basic #immunology, #immunotherapy & #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, & #inflammation. We remain grounded in our commitment to publishing studies that push the boundaries of our knowledge forward 👉 rupress.org/jem/collecti...

🎉🥂 our @jem.org paper “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” is in the 2025 Best of JEM collection This work was led by @benjbroom.bsky.social @wehi-research.bsky.social check out the original thread.. bsky.app/profile/groo...

Journal of Experimental Medicine@jem.org · 8mo ago

The 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 highlights research in basic #immunology, #immunotherapy & #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, & #inflammation. We remain grounded in our commitment to publishing studies that push the boundaries of our knowledge forward 👉 rupress.org/jem/collecti...

Another fantastic @ASI annual meeting, with @benjbroom.bsky.social (New Investigator finalist) and @brigetteduckworth.bsky.social (Symposia session) sharing the latest work from our lab. Loved catching up with old friends and hearing the current research from this brilliant network.

Thrilled to make the cover of @natimmunol.nature.com this month. A version of this warhol-inspired image has been in my head almost since we first conceived this Tfh diversity project (many, many years ago) @wehi-research.bsky.social

🎓 PhD positions available @MonashUni Join our lab to explore how neurons and immune cells shape gut immunity! 🧬 Single-cell RNAseq 🔬 3D imaging 🧠 Neuro-immune interactions 👥 Great mentoring & collaborations Apply now 👉 tinyurl.com/Seilletlab

A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health. Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity. www.wehi.edu.au/news/fast-fo...

🚨 New publication alert! 🚨 Thrilled to share our latest research out today in @jclinical-invest.bsky.social! This work is another great outcome of my amazing clinical research partnership with first author Samantha Chan and RMH. @wehi-research.bsky.social #immunology #research #JCI

Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com @wehi-research.bsky.social @benjbroom.bsky.social

WEHI (The Walter and Eliza Hall Institute of Medical Research)@wehi-research.bsky.social · last yr.

Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination. Published in @jem.org www.wehi.edu.au/news/vaccine...

Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination. Published in @jem.org www.wehi.edu.au/news/vaccine...

Our May issue is here! rupress.org/jem/issue/22... Cleary et al. (doi.org/10.1084/jem....) developed a new intravital technique for imaging pulmonary lymphatics. The cover depicts a 3D projection of a whole lung lobe with lymphatics (purple) and smooth muscle (white) labeled.

@benjbroom.bsky.social et al. @groomlab.bsky.social show that transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection. rupress.org/jem/article/... 📘 In JEM #Immunology Collection: rupress.org/jem/collecti... #AAI2025

This year's JEM #Immunology collection highlights recent findings in the field of B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. 👉 rupress.org/jem/collecti... #AAI2025

Thrilled to share our work now published on @cp-immunity.bsky.social . Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.

Immunity@cp-immunity.bsky.social · last yr.

Online now: Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis

You’re invited! Celebrate the Day of Immunology at WEHI on 29 April. 🔹Hear from top scientists 🔹Discover the new Snow Centre for Immune Health 🔹Go behind the scenes with a lab tour 🔹Enjoy morning tea & meet the team Register now - www.immunology.org.au/events/-ASI-...

Happy one week of my @jem.org paper! Our work from the @groomlab.bsky.social at @wehi-research.bsky.social identifies using early IFN-I blockade alongside mRNA vaccination to direct CD8+ T cell positioning in the lymph node to drive Tscm cell differentiation and enhance vaccine protection

#WeekendRead! #InterferonFriendOrFoe! @benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection

Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” @wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social Thread below.

Journal of Experimental Medicine@jem.org · last yr.

@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...

@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...

So lucky to be in a lab that does great science AND indulges in a weird photoshoot 🫶 Happy holidays!

Joanna Groom@groomlab.bsky.social · 2y ago

Please enjoy the 2024 edition of our #AwkwardLabPhoto Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social Credits: Creative vision and execution: @benjbroom.bsky.social Wardrobe: @brigetteduckworth.bsky.social Best pose (always): @raymondqin.bsky.social