Thrilled that Laura will be joining WEHI Immunology as the inaugural Sir Gustav Nossal Professor of Immunology 🎉 🥂 🙌

WEHI (The Walter and Eliza Hall Institute of Medical Research)@wehi-research.bsky.social · 6mo ago

We’re proud to welcome Prof Laura Mackay as our first Sir Gustav Nossal Professor of Immunology – advancing Sir Gus’ remarkable legacy, thanks to the generosity and vision of the Nossal family. More: www.wehi.edu.au/news/world-r...

The Szilard Point is not some theoretical event horizon. It is where we are at right now. When the total cost of competing for a grant exceeds the value of available funding the system is seriously broken. We need innovative granting schemes and solutions not more of the same hunger games.

Point of no returns: researchers are crossing a threshold in the fight for funding

With so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.

nature.com

Hey "Friends" The 2025 edition of our #AwkwardLabPhoto celebrates an incredible year of growth, publications, promotions, PhD submissions and grads I feel immensely proud and grateful to be part of this team

🎉🥂 our @jem.org paper “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” is in the 2025 Best of JEM collection This work was led by @benjbroom.bsky.social @wehi-research.bsky.social check out the original thread.. bsky.app/profile/groo...

Journal of Experimental Medicine@jem.org · 8mo ago

The 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 highlights research in basic #immunology, #immunotherapy & #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, & #inflammation. We remain grounded in our commitment to publishing studies that push the boundaries of our knowledge forward 👉 rupress.org/jem/collecti...

Fantastic to wrap up the year with a lab retreat at CERES East Brunswick: Celebrating some nice wins in 2025 and setting us up for 2026 and beyond @wehi-research.bsky.social @benjbroom.bsky.social @brigetteduckworth.bsky.social @raymondqin.bsky.social @chinweetan.bsky.social

2025 lab photo shoot has happened! While we're deciding on the final cut, flash back to last years entry. Is anyone else is up for the #AwkwardLabPhoto challenge... or is this just an "us" thing 🤷‍♀️

Joanna Groom@groomlab.bsky.social · 2y ago

Please enjoy the 2024 edition of our #AwkwardLabPhoto Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social Credits: Creative vision and execution: @benjbroom.bsky.social Wardrobe: @brigetteduckworth.bsky.social Best pose (always): @raymondqin.bsky.social

Cytokines 2026 in Glasgow (Oct 18-21) has an incredible Scientific Organizing Committee! Simon Jones, Iain McInnes, Clare Bryant, Clare Lloyd, and Luke O'Neill creating the program. This one's going to be special. Details: 2026.cytokinesociety.org

Another fantastic @ASI annual meeting, with @benjbroom.bsky.social (New Investigator finalist) and @brigetteduckworth.bsky.social (Symposia session) sharing the latest work from our lab. Loved catching up with old friends and hearing the current research from this brilliant network.

Jacques Miller? “It started by taking a thymus out of a mouse,” said Jo Handelsman, the director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison. “Who would have thought that would be an exciting idea for the future of medicine?”

Thiago Carvalho@cyrilpedia.bsky.social · 10mo ago

'All three awards (...) honored achievements rooted in fundamental research from decades ago. Some experts interpret the selections by the Royal Swedish Academy of Sciences as representing the importance of slow, basic science, work pursued out of a desire to better understand the world.'

Thanks @10xgenomics.bsky.social for the shout out and for making your data publicly available Why waste precious resources ($$) to reinvent data that already exists? Cool human datasets ready to go (Although now we have scratched the spatial itch, we may need to do more @chinweetan.bsky.social 🤔)

Millennium Science@mscience.bsky.social · 10mo ago

How do cytokines tune immune helpers? Nature Immunology study from @groomlab.bsky.social ’s lab at @wehi-research.bsky.social used @10xgenomics.bsky.social single-cell & spatial tech to map T follicular helper (TFH) cells diversity. 🔗 www.nature.com/articles/s41... #Immunology #SpatialBiology

Today is the last day to make a submission! You don't have to fill in the survey l, you can just upload a letter or even a video 🫵🏻Advocate for fundamental research👊🏻 @nhmrc.bsky.social need your feedback to develop the best strategy for the future of Australian medical research Link in the 🧵

Sophia Davidson@sciencesophie.bsky.social · 10mo ago

Dear Everyone, I've read the #NHMRC draft strategy and I have notes ... So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵 This is a repost from X because you all need to know! #NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience @nhmrc.bsky.social

Dear Everyone, I've read the #NHMRC draft strategy and I have notes ... So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵 This is a repost from X because you all need to know! #NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience @nhmrc.bsky.social

"Biology is messy and sometimes we need to embrace the mess" www.nature.com/articles/s41... Huge thanks to Amy Weinmann and Danielle Chisolm for beautifully highlighting our work and the importance of our approaches @natimmunol.nature.com

TFH cell programs by pathogen and species - Nature Immunology

CD4+ T follicular helper (TFH) cells that develop in response to a range of pathogens share aspects of a common gene signature. However, cytokine environments, rather than pathogen class, shape diversity in programming potential.

nature.com

WEHI scientists led by @groomlab.bsky.social‬ @chinweetan.bsky.social map how Tfh cells tailor instructions based on infection type. A step toward smarter vaccines and therapies. 📄 In @natimmunol.nature.com: www.nature.com/articles/s41... 🔗 Read more: www.wehi.edu.au/news/unlocki...

Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com www.nature.com/articles/s41... This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social Thread below...

Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity - Nature Immunology

Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and new tools to interrog...

nature.com

Abstract deadline extended to Monday, June 30! And travel grants are still available to student and post-doc members. Don't miss out - REPOST to share the info with others.

International Cytokine & Interferon Society (ICIS)@cytokinesociety.bsky.social · last yr.

Don't forget 📆 Abstract deadline for poster or oral presentations is June 18. Please repost to your network to spread the word! More info or register at seattle.cytokinesociety.org

🌏 Make your mark in Melbourne! 🌏 We are looking for innovative researchers to join WEHI as Laboratory Heads and help lead the next wave of biomedical discovery. For more information and to apply 👇

Make your future Melbourne

Lead the next wave of biomedical discovery

wehi.edu.au

🧠🍔 Just 48 hours on a high-fat diet can weaken gut immunity. Our new study shows saturated fats rapidly impair ILC3s! Proud to see this featured by @wehi-research.bsky.social as I continue to explore these questions @monashuniversity.bsky.social with the IMI Lab!

WEHI (The Walter and Eliza Hall Institute of Medical Research)@wehi-research.bsky.social · last yr.

A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health. Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity. www.wehi.edu.au/news/fast-fo...

ICYMI: explore our #Immunology collection, highlighting B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. 👉 rupress.org/jem/collecti... #AAI2025

So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...

Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com @wehi-research.bsky.social @benjbroom.bsky.social

WEHI (The Walter and Eliza Hall Institute of Medical Research)@wehi-research.bsky.social · last yr.

Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination. Published in @jem.org www.wehi.edu.au/news/vaccine...

Thanks to @cytokinesociety.bsky.social Signals+ for highlighting our recent work @benjbroom.bsky.social @wehi-research.bsky.social

International Cytokine & Interferon Society (ICIS)@cytokinesociety.bsky.social · last yr.

Proud to share the latest publication from ICIS Member Joanna Groom's lab @groomlab.bsky.social at WEHI: Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection signals.cytokinesociety.org/2025/04/14/b...

#WeekendRead! #InterferonFriendOrFoe! @benjbroom.bsky.social @groomlab.bsky.social &co show @jem.org that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection

Gonna guess immunologists will regret the "precursor of exhausted" T cell name in the future.

Journal of Experimental Medicine@jem.org · last yr.

@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...

Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” @wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social Thread below.

Journal of Experimental Medicine@jem.org · last yr.

@benjbroom.bsky.social et al. @groomlab.bsky.social show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells rupress.org/jem/article/...

Transient inhibition of type I IFN enhances CD8+ T cell stemness and vaccine protection @jem.org @groomlab.bsky.social @benjbroom.bsky.social doi.org/10.1084/jem....

Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11 wellcomeopenresearch.org/articles/9-3...

Kicking off the new year searching for a postdoc to join our team @wehi-research.bsky.social Apply now and spread the word

Research Officer

Job Title Research Officer Job Description An excellent opportunity is available for a Research Officer to join the Groom Laboratory in the Immunology Division at Australia’s pre-eminent biomedical re...

wehi.wd3.myworkdayjobs.com

Congratulations @jenjuno.viralvaxlab.com and team for this essential update to the field Cue the purchase of anti-CXCR4 to increase antigen-specificity in CD4 T cell activation assays

Jennifer Juno@jenjuno.viralvaxlab.com · 2y ago

As a first #ImmunoSky post, I’m excited to share our latest pre-print, by the fantastic Mitchell Zheng! www.biorxiv.org/content/10.1... Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9

So lucky to be in a lab that does great science AND indulges in a weird photoshoot 🫶 Happy holidays!

Joanna Groom@groomlab.bsky.social · 2y ago

Please enjoy the 2024 edition of our #AwkwardLabPhoto Feel incredibly proud and privileged to work with this crew @wehi-research.bsky.social Credits: Creative vision and execution: @benjbroom.bsky.social Wardrobe: @brigetteduckworth.bsky.social Best pose (always): @raymondqin.bsky.social