New paper alert! In this paper we were interested to formally test some of the assumptions made by computational psychiatrists - assumptions about parameter recoverability, reliability and validity. www.cambridge.org/core/journal...

The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms | Psychological Medicine | Cambridge Core

The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms - Volume 56

cambridge.org

Amazing few days at Yale for #CPConf2026 #CPC2026! Honoured to have received a Travel Award and selected for a Poster Spotlight talk. ✨ Feeling very grateful for the opportunity and inspired by the innovative work being carried out by so many talented researchers in computational psychiatry. 😊

Finally, congratulations to all travel & poster award winners! The best part of #CPC2026 was seeing trainees & fellow early career scientists share their work with such creativity & rigor. Gives me so much hope for the future of this field 🧠📊 /fin (and now off to catch up on 5 days of sleep!)

What a week! #CPC2026 was amazing, and it was such a joy to co-organize & host it here at Yale with @robbrutledge.bsky.social @xiaosigu.bsky.social @yiplab.bsky.social @francesghart.bsky.social & Al Powers & Katie Myerscough (our MVP!) Some highlights... 🧵

On Wednesday, @bethanbarrett.bsky.social will be presenting results from an aversive version of the two step task where we find intriguing links between model-based avoidance and anxiety/depression (Poster B48, and a poster spotlight!) Work with @efouragnan.bsky.social

Excited to be heading to #cpconf in New Haven and looking forward to what looks like a really brilliant programme! We have some exciting new work being presented by our brilliant students and postdocs 👇👇👇

🧠 Focused ultrasound changes emotional processing 🔊 In a new study published in Neuron today, we stimulated the human amygdala using transcranial ultrasound stimulation (TUS) and show it plays a causal role in detecting and resolving emotional ambiguity.

Johannes Algermissen@johalgermissen.bsky.social · 4mo ago

Very happy our first paper using ultrasound stimulation (TUS) to stimulate the human amygdala (BLA) got out in @cp-neuron.bsky.social today! 🎉🥳🔊Great FUN with co-first authors @mirunmigyu.bsky.social @lilweb.bsky.social in @mkflugge.bsky.social 's lab! www.sciencedirect.com/science/arti...

Now online in @biologicalpsych.bsky.social CNNI - our paper showing that reliance on habitual responding in transdiagnostic compulsivity may be underpinned by uncertainty about learned environmental structure 📃 www.sciencedirect.com/science/arti...

Impaired Goal-Directed Planning in Transdiagnostic Compulsivity Is Explained by Uncertainty About Learned Task Structure

Diminished use of goal-directed (model-based) decision making is a hallmark of transdiagnostic compulsivity, promoting an overreliance on inflexible a…

sciencedirect.com

Toby Wise@tobywise.bsky.social · 2y ago

📰 New preprint! We show using computational modelling that transdiagnostic compulsivity is associated with greater uncertainty about learned task structure This work was led by Siri Sookud, starting during her MSc osf.io/preprints/ps...

I'm teaching Statistical Rethinking again starting Jan 2026. This time with live lectures, divided into Beginner and Experienced sections. Will be a lot more work for me, but I hope much better for students. I will record lectures & all will be found at this link: github.com/rmcelreath/s...

We're wrapping up for the year at BRIC, and what a year it was! After a good rest, we will be ready for more wonderful research in 2026. Happy Holidays, everyone!

New study out today in Nature Comms: www.nature.com/articles/s41..., in which we set out to test whether ultrasound could influence the reward-related learning computations of the nucleus accumbens, building on decades of work on dopaminergic prediction error and reinforcement learning. And it did.

Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity - Nature Communications

This study shows that non-invasive ultrasound to the human nucleus accumbens can modulate deep brain activity and enhance reward-guided learning, offering a potential alternative to invasive neuromodu...

nature.com

I updated a blog which I wrote a few years ago about PhD applications. There's a mix of reflections and practical tips which should be useful for anyone thinking about applying for a PhD (at predominantly UK institutions). Please share if it could be helpful! timothysandhu.github.io/blog/phd_blog/

Please read these two very important letters below in response to a recent case reporting a serious medical event following TUS ⤵️

Elsa Fouragnan@efouragnan.bsky.social · 9mo ago

A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing. Case: doi.org/10.1016/j.br... Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...

So great to share plans for my upcoming online study and broader PhD with brilliant minds at my first conference #BAP2025 and fantastic computational modelling workshop #CSC2025! osf.io/7fqbe