New paper alert! In this paper we were interested to formally test some of the assumptions made by computational psychiatrists - assumptions about parameter recoverability, reliability and validity. www.cambridge.org/core/journal...

The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms | Psychological Medicine | Cambridge Core

The recoverability, reliability, and generalizability of reward processing parameters and relation to mental health symptoms - Volume 56

cambridge.org

Amazing few days at Yale for #CPConf2026 #CPC2026! Honoured to have received a Travel Award and selected for a Poster Spotlight talk. ✨ Feeling very grateful for the opportunity and inspired by the innovative work being carried out by so many talented researchers in computational psychiatry. 😊

Honoured to receive a Poster Prize at #BAP2026 for my project investigating the Effects of Transcranial Ultrasound Stimulation (TUS) on Interoceptive Attention. I'm grateful to everyone who worked on this project, @camillanord.bsky.social and Veronica Forslund, who were at the conference, and...

Does problematic social media use involve the same dopamine-related reward mechanisms as addiction? That’s the question motivating the research I presented at the @bapsych.bsky.social Summer Meeting, involving a dopaminergic manipulation to probe the involved mechanisms. #BAP2026

Excited to be chairing/presenting at our post-doc symposium discussing the advancements (and challenges 🤫) of computational psychiatry with a ⭐️ line-up of @saramehrhof.bsky.social @yanivabir.bsky.social & Alicia Rybicki. If at #BAP2026, come join us today at 2pm ‼️

British Association for Psychopharmacology@bapsych.bsky.social · 2mo ago

Three high quality Post-Doc symposia will be running in parallel on Monday afternoon, 20th July, with subjects including computational psychiatry, long-term effects of stopping antipsychotics and antidepressants, and challenges of psychosis prediction modelling #BAP2026

Excited to share our new paper asking a simple question: Why do mental and metabolic health so often go hand in hand? We (@camillanord.bsky.social @hugofleming.bsky.social) tested whether shared neurocognitive signatures play a role in this relationship www.nature.com/articles/s41...

Computational phenotyping of effort-based decision-making in type-2 diabetes on and off semaglutide - Neuropsychopharmacology

Neuropsychopharmacology - Computational phenotyping of effort-based decision-making in type-2 diabetes on and off semaglutide

nature.com

🚨 Does social media use show established neurocognitive signatures of addiction? Concerns about social media addiction are widespread, yet whether platforms' design features actually engage the same neurocognitive pathways as established addictions has remained untested. doi.org/10.31234/osf...

Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃) Find the paper here: www.nature.com/articles/s41...

💥New paper out! Why do some people generalise threat more than others? We show that anxious people generalise more strongly, even after accounting for perceptual mistakes. A huge (!) thanks to @ondrejzika.bsky.social @nicoschuck.bsky.social and @bernhardspitzer.bsky.social

Communications Psychology@commspsychol.nature.com · 5mo ago

Anxiety is associated with increased generalisation of threat to similar stimuli. This paper dissociates perceptual mistakes from value generalisation and links stronger value-transfer to trait anxiety. @nicoschuck.bsky.social @ondrejzika.bsky.social www.nature.com/articles/s44...

We are recruiting! Postdoctoral research fellow at www.sdn-lab.org, studying the computational & neural basis of social decision-making. Birmingham is a fantastic & affordable place to live, with one of the youngest populations in Europe & over 600 parks. Please share! www.jobs.ac.uk/job/DQO275/p...

Postdoctoral Research Fellow in Social Decision Neuroscience at University of Birmingham

Explore an exciting academic career as a Postdoctoral Research Fellow in Social Decision Neuroscience. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

jobs.ac.uk

Over the years, I have written a few Jupyter/Rmd/Matlab notebooks that attempt to teach some statistical concepts, particularly in neuroimaging. You can find them here: www.mrc-cbu.cam.ac.uk/people/rik.h..., though I will say a bit more about each one in a number of posts over next few days.

❗️NEW OPINION PIECE 🗨 Want to find out how apathy might be more than evaluating cost and benefit? ⚖️ Then read on! V excited for the release of my first opinion piece on #apathy as a failure of active inference in @cp-trendsneuro.bsky.social with thanks to my co-author @cambridgeftd.bsky.social 😊

MRC Cognition and Brain Sciences Unit, University of Cambridge@mrccbu.bsky.social · 8mo ago

Apathy is a common symptom in a wide range of conditions with limited treatment. In this opinion article, we highlight a novel approach to apathy based on a reduction in confidence on action outcomes, & include testable hypotheses at a cognitive & neuroanatomical level: www.cell.com/trends/neuro...

Out now in Translational Psychiatry! www.nature.com/articles/s41...

Model-based planning is unaffected by ketamine, antidepressant and internet delivered cognitive behavioural therapy treatments in depression - Translational Psychiatry

Translational Psychiatry - Model-based planning is unaffected by ketamine, antidepressant and internet delivered cognitive behavioural therapy treatments in depression

nature.com

Kelly Donegan@kellydonegan.bsky.social · 2y ago

Null findings are important ‼️ Excited to share my latest work finding model-based planning does NOT improve following ketamine 💉, antidepressant 💊, or iCBT 👩‍💻 treatments 🧵👇🏻

🧵 New paper! Five years ago, we, @fuzefovsky.bsky.social, Dr Alal Eran, and I, introduced empathic disequilibrium, the mismatch between cognitive and emotional empathy. In our article published in @cp-trendscognsci.bsky.social, we discuss the theoretical and clinical implications of the concept.

Empathic disequilibrium: theoretical implications and clinical relevance

Empathy is central to social cognition, yet efforts to link it with neurodiverse and clinical conditions have yielded contradictory findings, often reinforcing a deficit-focused narrative that conflic...

cell.com

I updated a blog which I wrote a few years ago about PhD applications. There's a mix of reflections and practical tips which should be useful for anyone thinking about applying for a PhD (at predominantly UK institutions). Please share if it could be helpful! timothysandhu.github.io/blog/phd_blog/

Congrats to Ella for her new paper! She asked a really interesting question about how the brain represents uncertainty during hidden state inference, and in a lovely crossover with theoretical work, she shows that in mice, acetylcholine dynamics play a crucial role. www.biorxiv.org/content/10.1...

Acetylcholine reflects uncertainty during hidden state inference

To act adaptively, animals must infer features of the environment that cannot be observed directly, such as which option is currently rewarding, or which context they are in. These internal estimates,...

biorxiv.org

This work is now out in Nature Communications! 🎉 Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry: www.nature.com/articles/s41467-025-64702-6 Huge thanks to our amazing team! @beckyneuro.bsky.social @campsydept.bsky.social @camneuro.bsky.social

Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry - Nature Communications

Using computational modelling and neurochemical analysis, this study shows how motor cortex excitatory signals guide belief updating and adaptive learning in uncertain environments.

nature.com

Nazia Jassim@naziajassim.bsky.social · last yr.

New preprint alert! How do we process uncertainty, and how do neurometabolites shape this?🧠Here we combine computational modeling + 7T MRS to answer these questions: www.biorxiv.org/content/10.1... With Peter Thestrup Waade, Chris Mathys, Frederike Petzchner, @beckyneuro.bsky.social & others! 🧵(1/4)

Long overdue update prompted by submitting my hardbound thesis: I successfully defended my PhD earlier this year and have started a postdoc with @beckyneuro.bsky.social! Excited for more adventures in uncertainty with an amazing team.

Mental and metabolic health are closely linked - but what drives this connection? In our new theory paper, we (w/ @camillanord.bsky.social & @hugofleming.bsky.social g.bsky.social) propose dysregulation of interoceptive energy allostasis as a key mechanism. www.science.org/doi/10.1126/... 🧵 1/n

An interoceptive model of energy allostasis linking metabolic and mental health

Interactions between metabolic interoception and regulation may drive comorbidity between mental and metabolic ill-health.

science.org

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

so, so excited to share our new theory which endeavours to answer why depression and poor metabolic health go hand-in-hand: "An interoceptive model of energy allostasis linking metabolic and mental health" 💪🧠🔋 @saramehrhof.bsky.social @hugofleming.bsky.social osf.io/preprints/ps...