1/ Mitochondrial Na⁺ links metabolism, Ca2+ signaling and disease. We know how it gets in, how it gets out, and proteins that use it. But: we've never actually seen Na⁺ in single mitochondria in live cells. We started with an unusual observation, went down a rabbit hole & found some cool biology .
Björn Högberg
@bjornhogberg.bsky.social
Biophysicist, Professor at Karolinska Institutet in Stockholm Sweden.
I'm very grateful for all the support from the Wallenberg foundation that my lab has got over the years!
Our lives depend on cells communicating with each other. Researchers at @ki.se are now attempting to understand how groups of proteins on the surfaces of cells are structured, and how they interpret and transmit signals to their surroundings. #research @bjornhogberg.bsky.social tinyurl.com/4r6ahpkm
My department is recruiting! Come and start your new lab at the Karolinska Institutet in Stockholm! ki.varbi.com/en/what:job/...
Assistant Professor in Biomedical Science
Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,
ki.varbi.com
Feels like this paper on protein-templated DNA synthesis by a natural enzyme warrants some comment. So here's a 🧵. /1 www.science.org/doi/10.1126/...
Science | AAAS
science.org
🧪🧬 You can now play Minecraft with DNA nanotechnology! In our latest preprint we introduce DNA polycubes platform: A modeling driven system, where we use SAT-solvers+multiscale simulations to design 3D finite-size structures that assemble in high yield chemrxiv.org/doi/full/10....
Post-doc positions in my lab. Come join us in Stockholm! ki.varbi.com/en/what:job/... ki.varbi.com/en/what:job/...
Weird statement by Rutte. First, it is obviously wrong. Given time and the necessary investments, Europe can of course defend itself without U.S. And second: Why undermine European deterrence like that? This message increases the risk that Putin will try to exploit the current fracture in NATO.
“If anyone thinks here ... that the European Union or Europe as a whole can defend itself without the U.S., keep on dreaming,” he told lawmakers on the European Parliament’s defense and foreign affairs committees. “You can't.” @politico.eu www.politico.eu/article/euro...
When Europe shows its true strength, dictators back down. Apply this lesson to Russia.
Our new paper is out! Tracking the stability of DNA origami in-vivo is typically done with fluorescence, but are they still attached to intact DNA nanostructures? Here we introduce PLASTIQ, a method to quantify the structure of DNA nanostructures using tiny blood samples, ligations and PCRs!
full video, obtained by NBC News, that was apparently filmed on a cell phone by the ICE officer who shot Renee Good
It's clear this is the "shooting someone on 5th Avenue" moment right? No one is still waiting for him to be actually there in Manhattan holding the gun?
Nanopore sequencing of peptides, exciting possibilities ahead also for the microprotein field.
Latest #CDlab paper on nanopore protein sequencing now published in JACS: pubs.acs.org/doi/full/10.... Here, Justas Ritmejeris, Xiuqi Chen, collaborator Bauke Albada, and me developed a conjugation chemistry strategy for nanopore sequencing of natural peptides!
THREAD The first full year of tracking research on @bsky.app Hi, we are Altmetric, and we track how research is communicated across the web. We now have one full calendar year of Bluesky research data and thought we'd have a looksie.
So the EU could not agree on using the frozen Russian assets to fund Ukraine. Are we trying to be the new Switzerland? “Let us take care of all that money while you bomb and rape your neighbor.”
Björn Högberg
bjornhogberg.micro.blog
These arguments come up regularly, that science funding shouldn’t require grant applications because they waste time. But what is the alternative? To rely on universities' internal politics to be able to efficiently... https://bjornhogberg.micro.blog/2025/12/13/these-arguments-come-up-regularly.html
Björn Högberg
bjornhogberg.micro.blog
Latest #CDlab paper out in Molecular Cell! see this thread by @RomanBarth2
🚨New paper out! In our @MolCellNews paper, we solve a piece of the puzzle of how our genome folds. We found the two specific molecular "brakes" in the CTCF protein that stop DNA loop extrusion. One of the final pieces of my PhD! tinyurl.com/29uuc5by
Ukraine accomplished to pass a UN resolution that recognizes the tragedy of Chornobyl - NOT as RU spells is “Chernobyl”; and Russia’s fault. For years, they’ve claimed their narrative passing THEIR resolutions. For the first time Ukraine accomplished to recognize the truth. Check who voted against
Ytterligare 27 lovande forskare får nu ta del av Knut och Alice Wallenbergs Stiftelses femåriga grundforskningsanslag. Läs mer om deras forskning: kaw.wallenberg.org/wallenberg-a...
for those claiming "my head went to putin instead of trump" - no. The russian "logic" is to control trump and his behavior. Someone involved, should know. This was before Trump's first term, during, after and is now. Nothing has changed. Both pro and anti kremlin messaging is kremlin approved.
Join us for the inaugural annual Ernest Arenas Memorial Lecture at the Nobel Forum at @ki.se. with Prof. Roger Barker, University of Cambridge "Repairing the human brain using transplants - is it possible? The story of Parkinson's disease" Tuesday November 25th at 15:00 news.ki.se/calendar/the...
The Ernest Arenas Memorial Lecture: Repairing the human brain using transplants- Is it possible? The story of Parkinson's disease.
Welcome to The Ernest Arenas Memorial Lecture with Professor Roger Barker, Professor of Clinical Neuroscience at the University of Cambridge and Consultant Neurologist at Addenbrooke's Hospital.
news.ki.se
IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇
This video is worth watching. It's easy to lose track of all the fraud going on right now. youtu.be/JMEJTORMVN4?...
crypto billionaire pardon is insane
YouTube video by voidzilla
youtu.be
A few comments on Trump's dealings with Ukraine: 1. He turned against Zelensky when Zelenky refused to falsify evidence against the Bidens. 2. At that time, Trump & Giuliani worked with men such as Andriy Derkach that US intelligence verified as belonging to Russia intelligence
On this date in 1939, the USSR invaded Poland in cooperation with its ally, Nazi Germany. www.hachettebookgroup.com/titles/timot...
Bloodlands
From the author of the international bestseller On Tyranny, the definitive history of Hitler’s and Stalin’s politics of mass killi...
hachettebookgroup.com
A must read for any (systems) biologist! www.cell.com/cell-systems...
Should biology put complexity first?
The dictum “Everything should be made as simple as possible, but no simpler” poses a problem for biology. How simply can it be told without doing damage to its complex nature? The answer might be foun...
cell.com