This one was in the pipeline for too long! One more great collab with @synbiojazz.bsky.social. This has some cool nano tools and a really interesting comparison between PCC 7942 and UTEX 2973. Check it out #teamcyano

Cyanotrans@cyanotrans.bsky.social · last wk.

Employing Nanotechnology to Enhance Ethanol Production in Two Synechococcus elongatus Strains chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Some more "legacy" of CRC 1208 @hhu.de: A brief up-to-date review of crowding effects in biological membranes - diversity of consequences, and approaches to mimic and to quantify. Thanks to Laura Hartmann @uni-freiburg.de for joining, and COSB for the invitation www.sciencedirect.com/science/arti...

Crowding at the cellular membranes: Emerging physiological roles and novel study approaches

Cellular membranes are essentially complex and heterogeneous assemblies. The lipid bilayer forms the basis of the membrane architecture, and the assoc…

sciencedirect.com

OK, not a "tremendous breakthrough", but it is nice to have it completed - the first project in the group, started after moving to @hhu.de years ago, as a part of CRC 1208 (1st C is for "collaborative"). Thanks to all the co-authors for the joint effort and resilence ✊🤓 www.jbc.org/article/S002...

Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase

The lipase LipA from Pseudomonas aeruginosa is an extracellular enzyme that plays an important role in bacterial infections. Prior to its export via the type II secretion system, LipA requires the cog...

jbc.org

We have an opening for a motivated & skilled Doctoral researcher in the group (Düsseldorf, Germany). Candidates with strong background in Biophysics/Biochemistry/Structural biology are welcome to apply. Applications are possible exclusively via the University portal: karriere.hhu.de/index.php?ac...

Doctoral Researcher in membrane protein biophysics / biochemistry (m/f/d)

karriere.hhu.de

We are on air! Congratulations to everyone behind the story ❤️‍🔥 and thanks to @embojournal.org for providing the stage! link.springer.com/article/10.1...

Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC - The EMBO Journal

The Sec translocon and the YidC/Oxa1-type insertases universally mediate biogenesis of α-helical membrane proteins, but the molecular basis of their cooperation has remained disputed. Recent discovery...

link.springer.com

„Schleuse“ für sperrige Fracht: Neue Details zum Transport von großen Proteinen durch Membranen Wie große Proteine Membranen in Zellen passieren können, ohne diese zu zerstören, zählt zu den großen offenen Fragen der Zellbiologie. Mit... weiterlesen

I learned so much from watching past editions of @ccpem.bsky.social Spring Symposium, so I agreed to my talk being recorded even though this is stepping well out of my comfort zone (public speaking isn't my strongest skill). Anyway, here is the recording: www.youtube.com/watch?v=AKTf... #CCPEM

Atomic resolution structure of spinach rubisco reveals protons and dynamics | Guillaume Gaullier

YouTube video by CCP-EM

youtube.com

While the SecYEG-YidC manuscript is progressing towards publishing (on paper, for real!), the model of the active complex is already accessible (more to come): www.rcsb.org/structure/9RBF

RCSB PDB - 9RBF: Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC

Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC

rcsb.org

Kedrov Lab @ HHU@kedrov-lab.bsky.social · 2mo ago

That celebration has waited for a long time... One year ago we uploaded the preprint and started the endeavor through the peer-reviewing. Lots of emotions on the way 🎭, lots of work, and quite some learning on "friend or foe"... Probably, deserves another post 🤫 But now - the paper is accepted!

Fully-funded PhD position available in my group in Turku, Finland to explore extracellular electron exchange between photosynthetic and non photosynthetic microorganisms. Application open until 3 Aug, position starts Sept-when suitable for best candidate ats.talentadore.com/apply/vaitos...

Doctoral researcher position, molecular plant biology

We are looking for a candidate to undertake a PhD on extracellular electron exchange between photosynthetic and non-photosynthetic microorganisms, focusing on underlying molecular mechanisms and regul...

ats.talentadore.com

That celebration has waited for a long time... One year ago we uploaded the preprint and started the endeavor through the peer-reviewing. Lots of emotions on the way 🎭, lots of work, and quite some learning on "friend or foe"... Probably, deserves another post 🤫 But now - the paper is accepted!

Kedrov Lab @ HHU@kedrov-lab.bsky.social · last yr.

Very special feelings to announce this one... A project that started like 10 years ago is reaching the finish line, ready to shine. In a dream-team with @beckmannlab.bsky.social we solved the long-chased structure of the active membrane protein insertase SecYEG-YidC www.biorxiv.org/content/10.1...

Our atomic resolution structure of Rubisco just got featured in @quantifoil.bsky.social newsletter. Check it out for a beautiful structure, visualized active site protons and novel mechanistic insights into one of the most important and abundant protein on Earth. doi.org/10.64898/2025.12.22.696010

So great to see our structure of chlorophyll synthase on bioRxiv! Thanks to amazing collaboration with Anna Wysocka, Felix Morey-Burrows, Andy Hitchcock and Roman Sobotka, and everyone else involved! @UniOsnabrueck @AlgatechTrebon @sheffielduni #cryoEM #photosynthesis #cyano

Postdoc position available to join my team in Turku, Finland to explore light-activated extracellular electron uptake in microorganisms. Application open until end of June, position starts August-when suitable for best candidate. Please share/apply ats.talentadore.com/apply/tutkij...

Post-doctoral researcher, Molecular Plant Biology, at Turku, Finland

We are seeking a Postdoctoral Researcher to investigate extracellular electron uptake in photosynthetic bacteria (cyanobacteria), focusing on underlying molecular mechanisms and regulation, and with c...

ats.talentadore.com

The small protein SbtC is a functional component of the CO2 concentrating mechanism in Synechocystis sp. PCC 6803 academic.oup.com/plphys/artic...

The small protein SbtC is a functional component of the CO2 concentrating mechanism in Synechocystis sp. PCC 6803

A previously non-annotated, CO2-controlled gene was identified in the cyanobacterium Synechocystis sp. PCC 6803 that encodes a small protein contributing t

academic.oup.com

CyanOperon: An Operon Building Expansion for the CyanoGate MoClo Toolkit | ACS Synthetic Biology pubs.acs.org/doi/10.1021/...

CyanOperon: An Operon Building Expansion for the CyanoGate MoClo Toolkit

Operons are gene clusters controlled by a single promoter that enable coordinated translation from a single mRNA. Here we describe an expansion of the CyanoGate MoClo toolkit to assemble synthetic ope...

pubs.acs.org

For those that think they are proteomics experts because they pack their own columns, these authors take it to another level by synthesising their own stationary phase.

PastelBio@pastelbio.bsky.social · 3mo ago

High‐Throughput Single‐Cell‐Resolved Spatial Proteomics Enabled by an Ordered Colloidal Crystal Column onlinelibrary.wiley.... --- #proteomics #prot-paper

#Publication: "Curation of #MassSpectrometry #ReferenceData for Improved Identification and #Dereplication of #Cyanobacterial Specialized #Metabolites" in Journal of #NaturalProducts #OpenAccess 2905 highly curated reference spectra of 150 metabolites now in #Massbank doi.org/10.1021/acs....

Thanks to @mibinet.bsky.social for hosting this edition of INSPIRE with Prof. Annegret Wilde @freecyano.bsky.social from @uni-freiburg.de! At INSPIRE, a collab between CEPLAS, MibiNet and @trr341.bsky.social we invite women scientists to share their research and personal career journey. Great talk!

This one is for local #bioeconomy #novelfood #spirulina enthusiasts in Jena: Come join us for the talk “From Bench to Bowl: Navigating the Regulatory Maze for Cyanobacterial Food Products” by Gunnar Muhlstädt (Puevit, Algenwerk Dresden) 📅 28 April 2026 🕓 4:00 pm (c.t.) 📍 HS Planetarium 1, Jena

Photosynthetic bacteria helped shape Planet Earth. Among them cyanobacteria—microbes that produced the oxygen in Earth’s atmosphere & made complex life possible. They have captivated scientists for decades by offering insights into how life evolved from single cells into multicellular organisms.

Cyanobacteria are an ancient clade of phototrophic prokaryotes. But out of all the cyanobacteria available, why did Synechocystis sp. PCC 6803 become the default laboratory model? This #JBacteriology review offers insights: asm.social/2TD

In need of algal culture media to grow them all? Find them here: www.sciepublish.com/article/pii/...

Three New Synthetic Algal Culture Media to Grow Them All †

Three new synthetic algal culture media are described that have been used to cultivate ~12,000 diverse strains of (micro)algae, one culture medium for marine and brackish-water algae (ASP-MEL (Artific...

sciepublish.com

Our new preprint on detailing the molecular mechanisms of how the carbonic anhydrase activates it's activity upon encapsulation into alpha-carboxysomes is now live. Congrats to Nikole and @guillawme.fediscience.org.ap.brid.gy !

bioRxiv Biochemistry@biorxiv-biochem.bsky.social · 4mo ago

Molecular mechanism of redox regulation of the alpha-carboxysomal carbonic anhydrase CsoSCA https://www.biorxiv.org/content/10.64898/2026.04.02.716132v1

Single-molecule peptide sequencing through reverse translation of peptides into DNA www.nature.com/artic... --- #proteomics #prot-paper

Maybe the MAGA was “Make Algae Great Again”, as we push to the magic $2.50 a barrel for algae biodiesel 😭🧪

Our work on #hornwort #pyrenoids is finally out in @science.org! 🎉 We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...

An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants

In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...

science.org

David has been interested in “green” microbes since his early university years. academic.oup.com/plphys/artic... #WeAreASPB

Engineering synthetic co-cultures to be "needy" leads to unexpected consequences. We barely scratch the surface here, but get some interesting insights #biotech 🧪 www.sciencedirect.com/science/arti...

Characterising complex metabolic responses in an engineered, cross-feeding microbial co-culture using quantitative proteomics

Microbial communities play a key role in biogeochemical transformations in a wide range of ecosystems, but they also hold significant potential to enh…

sciencedirect.com

www.nature.com/articles/s41...

Mechanism and reconstitution of circadian transcription in cyanobacteria - Nature Structural & Molecular Biology

Fang et al. reveal how a bacterial circadian clock turns genes on and off at the right times of day and use the purified proteins to drive circadian gene transcription in a test tube for days.

nature.com