(1/3) For all centrosome/cilia enthusiasts 🗣️🗣️ From Pereira’s lab, we’re so happy to share our latest collab with @sauer-lab.bsky.social: Mega-ExM)! 🥳 Here, we pushed expansion microscopy to crazy scales (1500x 🤯) and used cilia and centrioles as some of our favorite test structures 🤭
(1/4) We are very excited to share our latest preprint from @sauer-lab.bsky.social: Mega Expansion Microscopy (Mega-ExM)! We combine iterative hydrogel expansion with whole-proteome NHS labeling and post-expansion immunostaining, reaching tunable expansion factors up to ~1500× in whole cells 🤯