Our new preprint is out!! The human brain runs on ~20 watts. Computers and modern AI systems require vastly higher energy. This gap raises a fundamental question: how does the brain compute so efficiently? In our new study, we take a critical step toward measuring and understanding this directly 1/3

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last mo.

Learning Shapes the Energy Cost of Neural Tasks https://www.biorxiv.org/content/10.64898/2026.07.01.735889v1

We are looking for a Research Technician! see job posting here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...

Research Technician - Ye Lab

Primary Work Address: 10550 North Torrey Pines Road, La Jolla, CA, 92037 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute (HHMI) advances the d...

hhmi.wd1.myworkdayjobs.com

Congratulations to the 2026 McKnight Scholars! Great to see many friends amongst this cohort! www.mcknight.org/news-ideas/2...

2026 McKnight Scholar Awards

The Board of Directors of The McKnight Endowment Fund for Neuroscience is pleased to announce it has selected ten neuroscientists to receive the 2026 McKnight Scholar Award.

mcknight.org

What's better than one #HHMIInvestigator being elected to the @nasonline.org? Ten! Meet the newest members, recognized by their peers for distinguished, ongoing contributions to original research: bit.ly/4cCxRuv.

I’m so proud of myself!

Ardem Patapoutian@ardemp.bskyverified.social · 4mo ago

Hey @odedrechavi.bsky.social, my not being recognized in scientific settings has become such a big perceived concern of my colleagues that for April Fools they made a T-shirt to address this fundamental problem 🤣🤣🤣. And check out the peacock-themed humble club logo. Thx, @liye-tsri.bsky.social!

Excited to share our latest work with @antihebbiann.bsky.social, revealing a top-down mechanism regulating the fragmentation of feeding, led by Tianbo Qi. www.biorxiv.org/content/10.6...

I had a great time talking to Meenakshi about my trajectory through neuroscience! Tune in for electric fish, imaging the hypothalamus, and trying to find a path in theory that stays relevant to the brain. Also, my early phd experiences of trying to do science when real life rears its head.

Stories of WiN@storiesofwin.bsky.social · 5mo ago

We apologize for the delay but our next profile is here! Dr. Ann Kennedy (@antihebbiann.bsky.social) combines theory & biological data to study how internal states shape social behavior by reconfiguring neural circuit dynamics. Follow the link to learn more! www.storiesofwin.org/profiles/202...

Chuffed to see our paper with @geneyeo.bsky.social finally published in @nature.com. www.nature.com/articles/s41... Very grateful to Fede, Susie, and Dave from my lab, and Sammi, Eric, and Pratibha from Gene's lab. What did we find? ⬇️ ⬇️ ⬇️

Single-cell and isoform-specific translational profiling of the mouse brain - Nature

Post-transcriptional regulation of mRNA translation was explored using Ribo-STAMP and single-cell RNA sequencing to reveal cell-type-specific and isoform-specific translation patterns across hipp...

nature.com

What if we could see 3D #biodistribution of cancer drugs at the cellular level... throughout an entire model animal? 🧐 A new paper from Li Ye's lab @scripps.edu, Zhengyuan Pang & Verina Leung et al. introduce a technique for doing just that. (1/3) 🧵

Thrilled to share our latest work--combining CATCH with whole-body HYBRiD imaging, leveraging click chemistry to visualize and identify drug-targeted cells across organ systems. Led by a brilliant team: former PhD student Ben Pang and former undergrad Verina Leung.

Cell - a Cell Press journal@cp-cell.bsky.social · 8mo ago

Now online! Mapping cellular targets of covalent cancer drugs in the entire mammalian body

Fellows-to-Faculty awardee Chen Ran maps the senses of internal organs. Receiving this award — which is currently open for apps — has been crucial in enabling his work: https://www.simonsfoundation.org/autism-and-neuroscience-innovators-awardees-share-their-research-at-the-annual-retreat/ #science

RIP Jim Watson. You inspired many of us to pursue a life in research. I wish you had made it easier for us to celebrate your legacy.

Nothing beats the ceremony of dragging a grant from my pending folder to dead grant folder hahaha (sometimes it did give a big relief though)

Deeply honored to receive this year's Tianqiao and Chrissy Chen Young Investigator Award from @sfn.org Grateful to all lab members and my mentors.

Society for Neuroscience@sfn.org · 9mo ago

Congratulations to the 2025 SfN award & prize recipients! Their dedication to advancing the understanding of the brain paves the way for future discoveries. SfN looks forward to celebrating their achievements at #SfN25. Learn about the recipients. 🔗 vist.ly/4cni8 #neurosky

Come be my newest colleague! Scripps neuro is an energetic and supportive department, and uniquely benefits from proximity to our intimidatingly awesome chem and drug discovery programs. Happy to chat about my experiences here so far!

Ardem Patapoutian@ardemp.bskyverified.social · 10mo ago

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost! apply.interfolio.com/174756

The NIH has awarded a $14.2M Director’s Transformative Research Award to a team led by Nobel Prize-winning neuroscientist @ardemp.bskyverified.social, Prof. @liye-tsri.bsky.social and Assoc. Prof. @xinjin.bsky.social to map interoception and build the first atlas of this hidden sixth sense.

Scripps Research-led team receives $14.2M NIH award to map the body’s “hidden sixth sense”

scripps.edu

Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain. A brief rundown... www.nature.com/articles/s41...

A parabrachial hub for need-state control of enduring pain - Nature

Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.

nature.com

Coming to #SfN2025 in San Diego? Come join our Neuroscience Symposium a day before on Nov 13! Hear from a fantastic speaker lineup and interact with vibrant audience in our community and beyond. Free registration link: www.eventbrite.com/e/dorris-neu...

Ardem Patapoutian@ardemp.bskyverified.social · 10mo ago

Attending #SfN2025 in San Diego☀️? Don’t miss the Dorris Neuroscience Center Symposium at @scripps.edu, happening right before the meeting. A great lineup of speakers to kick off your SfN week. Plan your trip accordingly and register for free here: www.eventbrite.com/e/dorris-neu... Please amplify!

Congrats to @xinjin.bsky.social @tinakim-neuro.bsky.social and many others!

Jason Shepherd@jasonsynaptic.bsky.social · last yr.

Love seeing friends and colleagues #slay! Congrats to @moriel-z.bsky.social @utah.edu for becoming a @hhmi.org Hrabowski scholar! Also congrats to @tinakim-neuro.bsky.social @xinjin.bsky.social @doctheagrif.bsky.social www.hhmi.org/programs/fre...

Talked to @KateZernike at @nytimes about my journey and the current moment for scientists in the U.S. “Ardem Patapoutian’s story is not just the American dream, it is the dream of American science.” Read the article here. No subscription required: www.nytimes.com/2025/06/03/u...

The U.S. Lit a Beacon for Science. Under Trump, Scientists Fear It’s Dimming

nytimes.com

Congrats to Assist. Prof. Chen Ran (@chenran.bsky.social), one of just 15 selected as a 2025 Searle Scholar! 🌟 His work on how visceral signals are encoded in the brain was recognized for its potential to elucidate disease mechanisms & inform new therapeutics. More: ow.ly/HtLM50VN8sN

Congratulations to @chenran.bsky.social on being named a Searle Scholar! searlescholars.org/2025/04/14/s...

SEARLE SCHOLARS PROGRAM NAMES 15 SCIENTISTS AS SEARLE SCHOLARS FOR 2025

Members of the new class of Searle Scholars pursue ground-breaking research in chemistry and the biomedical sciences. Each receives an award of $300,000 in flexible funding to support his, her, or …

searlescholars.org

Lots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS: www.sciencedirect.com/science/arti...

Interoceptive processing in the nucleus of the solitary tract

The interoceptive nervous system continuously monitors the status of visceral organs to synthesize internal perceptions and regulate behavioral and ph…

sciencedirect.com

Great collaboration with @liye-tsri.bsky.social @dlipomi.bsky.social, and Jonathan Long labs and led by Yu Wang and Yunxiao Zhang 2/2