So excited to serve as a Guest Editor w/ Professors Koichi Nakajo and Bikash Pattnaik for the upcoming special issue: @JPrecisionMed “Ion Channels in Precision Medicine: Mechanisms, Modeling and Therapeutic Innovation”

We are looking forward to your submissions! Reach out with a presubmission inquiry if you need more information!

The Journal of Precision Medicine: Health and Disease@jprecmed.bsky.social · last mo.

📣Call for Papers: Ion Channels in Precision Medicine 🧑‍⚕️ Guest Editors: Koichi Nakajo, Bikash R. Pattnaik, and Colleen E. Clancy 📅 Deadline: 31 December 2026 👇️ More information: www.jprecisionmedicine.org/call-for-pap...

CPMDS Research Highlight 🔬 CATVariant is a new open-access webserver for studying genetic variants, integrating population, clinical, structural, and literature data with computational predictors to help interpret variant effects. Read more: doi.org/10.1093/nar/... | Explore: catvariant.com

Maxime Lammens, Frank Bosmans et al. show how an auxiliary β1 subunit tunes the activity of the human Na+ channel NaV1.6, a key regulator of electrical signaling in neurons, linking channel structure to mechanisms that shape neuronal excitability. rupress.org/jgp/article/... #IonChannels

CPMDS Research Highlight 🔬 Computational models reveal how the autonomic nervous system regulates blood flow and blood pressure across molecular, cellular, and tissue scales, providing insights that could guide future precision cardiovascular therapies.

Smooth signals: computational insights into autonomic vascular control | American Journal of Physiology-Cell Physiology | American Physiological Society

The regulation of vascular tone underlies normal cardiovascular homeostasis, ensuring appropriate distribution of blood flow to tissues and maintenance of blood pressure. Computational modeling and si...

journals.physiology.org

New publication in Nucleic Acids Research describing CATVariant, an open-access web server for integrated protein variant interpretation. 🔗 Read the paper: doi.org/10.1093/nar/... 🌐 Try CATVariant: catvariant.com #Bioinformatics #PrecisionMedicine #Genomics #ProteinVariants #NAR #OpenScience

CATVariant: a web server for integrated protein variant interpretation across sequence, structure, population, and clinical evidence

Abstract. Efficient interpretation of the structural, functional, and clinical impact of protein variants remains a longstanding challenge. This difficulty

doi.org

@ucdcpmds.bsky.social · 2mo ago

CPMDS Research Highlight 🔬 CATVariant is a new open-access webserver for studying genetic variants, integrating population, clinical, structural, and literature data with computational predictors to help interpret variant effects. Read more: doi.org/10.1093/nar/... | Explore: catvariant.com

We're at #ICMSTokyo! 🔬 🗾 Koichi Nakajo, Reviewing Editor for the journal, is here to share more information about our mission linked to innovative strategies for ion channel research and drug development 💉 🥼 Kazuharu Furutani is pictured here with the journal's front cover! 📷

CPMDS Research Highlight 🔬 (Drs. Igor Vorobyov, Vladimir Yarov Yarovoy, Colleen E. Clancy) Researchers used advanced simulations to reveal how ligands dissociate from membrane receptors, uncovering hidden molecular pathways that could improve drug discovery and precision therapeutics. 💻

New research shows how AlphaFold can predict hERG ion channel states, improving drug safety screening and helping identify arrhythmia risks earlier in drug development. A major step toward safer, AI-driven therapeutics. #AI #DrugDiscovery Read more here: pmc.ncbi.nlm.nih.gov/articles/PMC...

Harnessing AlphaFold to reveal hERG channel conformational state secrets

To design safe, selective, and effective new therapies, there must be a deep understanding of the structure and function of the drug target. One of the most difficult problems to solve has been the re...

pmc.ncbi.nlm.nih.gov

🔬 CPMDS Research Highlight New research highlights how AI and digital health technologies are improving healthcare quality and patient safety through proactive, data-driven care, clinical decision support, telehealth, and better care coordination. #DigitalHealth pubmed.ncbi.nlm.nih.gov/40752934/

Health Care Quality and Patient Safety in the Era of Artificial Intelligence - PubMed

The integration of digital health technologies is revolutionizing health care quality and patient safety by shifting from reactive to proactive care models. Advances in electronic health records, clin...

pubmed.ncbi.nlm.nih.gov

🔬CPMDS Research Spotlight New research highlights how advances in cardiovascular ion channel and Ca²⁺ signaling research are shaping future therapies for heart disease, including arrhythmias and heart failure. ❤️🫀 Read more: pubmed.ncbi.nlm.nih.gov/41605640/

Associate Director for Computational Biomedicine Dr. Emilie Roncali recently gave a keynote on theranostics digital twins and in silico models at the Virtual Imaging Trials in Medicine workshop 2026!!

🔬 CPMDS Research Spotlight (Dr. Emilie Roncali): CFD is advancing cancer therapy by modeling blood flow & drug transport to improve targeting and reduce side effects. Integrating with imaging & AI could enable more personalized treatment. lnkd.in/deHn6Pp4 #CancerResearch #PrecisionMedicine

📣CALL FOR PAPERS📣 Organised and edited by @clancyatheart.bsky.social This Special Issue welcomes original research articles, reviews and perspectives that explore the intersection of New Approach Methodologies (#NAMs) with #precisionmedicine 🧬 📍 🔗 For more information👇️ buff.ly/lFDfYnV

Congrats to Frederick Ha who presented his research at the Undergraduate Research, Scholarship and Creative Activities Conference at UC Davis! Image Description: Frederick stands at the front of a classroom giving a presentation.

CPDMS Research Spotlight (Dr. Deborah Lieu): New research in Stem Cell Reports reveals insights into how cellular programs regulate stem cell behavior, deepening our understanding of development and advancing potential applications in tissue repair and disease modeling www.cell.com/stem-cell-re...

A humanized engineered heart tissue platform for cardiotoxicity assessment

In this article, Sun and colleagues develop a humanized engineered heart tissue platform by integrating human ventricular extracellular matrix with GCaMP6f-expressing hiPSC-derived cardiomyocytes. Thi...

cell.com

In this new #Review, Chiara Anna Giordani (@ucdcpmds.bsky.social) and @clancyatheart.bsky.social discuss #dose as a fundamental organizing principle in physiology. 💉 💊 🔗 Read it here: www.sciencedirect.com/science/arti...

Congratulations to Dr. Fred Meyers on receiving the 2026 ACTS Distinguished Educator: Mentorship Innovation Award! This honor recognizes innovative mentorship advancing translational science and supporting diverse researchers. Proud to celebrate this achievement! 🎉

New research shows common therapies, estrogen, metformin, statins, and vitamin D, may unintentionally affect regulatory T cells (Tregs), key to immune balance. Understanding these effects could help advance more precise, personalized care. pubmed.ncbi.nlm.nih.gov/41855744/

Deep Learning Echocardiographic Trajectories of Heart Failure With Preserved Ejection Fraction: A Retrospective Cohort Study - PubMed

Longitudinal phenomapping resulted in echocardiographic trajectories of cardiac structure and function with different clinical, laboratory, and survival characteristics. HFpEF is a dynamic condition, ...

pubmed.ncbi.nlm.nih.gov

🔬 Ionizing radiation reshapes heart cell function—not just tissue damage. Low–moderate doses: pro-arrhythmic High doses: improved electrical stability 🧠 Mitochondria drive these effects 💡 May help optimize radiotherapy & reduce cardiac risk 📖 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

Abstract figure legend Dose-dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate ....

physoc.onlinelibrary.wiley.com

Jan 14, 2026: The Data Science Seminar Series spotlighted theranostics & digital twins in cancer care. Emilie Roncali shared advances in liver, prostate & metastatic cancers improving diagnosis, treatment & outcomes. www.cancer.gov/about-nci/or... #CancerResearch #DigitalTwin #PrecisionMedicine

Theranostics and Digital Twins for Personalized Medicine

On January 14, the Data Science Seminar Series is tackling an intersection of two critical data science concepts in cancer research: theranostics and digital twins. By combining computational and clin...

cancer.gov

Congrats to Vladimir Yarov-Yarovoy on the GenScript Life Science Research Grant for his AI-driven drug discovery work! His research on ion channels could help treat arrhythmias and neuropathic pain. Selected from 500+ applications, an outstanding achievement!

Kensuke Sakata and Natalia Trayanova enlighten and delight in this new review in @jprecmed.bsky.social on cardiac digital twins!

The Journal of Precision Medicine: Health and Disease@jprecmed.bsky.social · 4mo ago

In this recent review article, Kensuke Sakata and Natalia Trayanova from @jhu.edu examine how #digitaltwins technology can facilitate mechanism-driven, personalized ablation planning and improve PsAF patient care 🫀 🔄 Read the article here: 👇️ www.jprecisionmedicine.org/article/S305...

Footage captured from passengers on an airliner above Florida, showing the exact moment the Artemis II mission lifts off.

Inamullah Inamullah from unisouthampton.bsky.social et al. explore the evolution of #retinal imaging techniques, the dire need for the integration of #AI-driven analysis, and the shift of retinal imaging from classical techniques to #oculomics 👁️ 🔎 🔗 📜 www.jprecisionmedicine.org/article/S305...

In this recent #Research article, Sarah Hersey of @qubelfastofficial.bsky.social et al. examine the interplay and #complexities of #pharmaceutical and diagnostic partnerships to deliver the promise of precision medicine 🧪 💉 📜 Read the work here: www.jprecisionmedicine.org/article/S305...

In this recent study, Fakher Rahim and Saeid Saeidimehr undertook a comprehensive integration of multi-omics data to identify novel immunological #biomarkers and repurposable drug targets for human #aging and frailty 💻️ 💊 Read their research👇️ www.jprecisionmedicine.org/article/S305...

🚨 New imaging breakthrough! #Research by Dax Yuhasz, Bitania Shewandagn & Patrick Jurney shows that holotomographic microscopy (HTM) can track #mitochondria in dividing cells label‑free and without damaging light exposure. 💡 Read the study here 👇️: www.sciencedirect.com/science/arti...

A team including Colleen Clancy published a primer on using digital twins in biomedical research—bridging AI, mechanistic models, and real data to create virtual representations of living systems. This approach can deepen our understanding of biology and improve future healthcare.

Digital Twins as New Approach Methodologies (NAMs) in Biophotonics Led by Moderator Dr. Colleen Clancy this panel explores how digital twins are transforming healthcare from AI-driven care to treatment optimization and device simulation shaping the future of medicine. spie.org/photonics-we...

SPIE Photonics West Special Event Digital Twins as New Approach Methodologies (NAMs) in Biophotonics

spie.org