📄 Recent review by Nicolae Moise et al. on correlative methods! 📣 The authors discuss the investigative power of both direct and indirect correlative methods, and the untapped potential of the latter in life science research! 👇️ Read the full article: buff.ly/MMdY0n7

Clodomir Santana, Martin Cadeiras and David A. Liem from @ucdavishealth.bsky.social and @ucdcpmds.bsky.social discuss how a precision medicine approach can help examine complex #pathophysiology and heterogeneous phenotype of #HFpEF 💡🫀 Read the article👇️ www.sciencedirect.com/science/arti...

Join our Editorial Board! 🎓️ We’re inviting nominations for new Editorial Board members to help shape the future of precision medicine. Self-nominations are warmly welcomed. Submit a statement of interest, CV and short biography to jpm@physoc.org by 30 November 2026.

🏆 Congratulations to Paula Dominguez-Gomez, Constantine Butakoff, Georg Rast, Borje Darpo, Mariano Vazquez and Jazmin Aguado-Sierra, winners of the inaugural Paper of the Year Award 2025! Read the winning paper👇️ www.sciencedirect.com/science/arti...

We're seeking articles translating cellular and molecular discoveries into precision medicine, including multiomics, cellular models, rare diseases, complex disorders and clinical applications. Submit by 31 December 2026 for no #OpenAcess fees! www.sciencedirect.com/special-issu...

Free Open Access Publication: Limited time offer ⏰ Submit your work by 31 December 2026 to enjoy fully waived #OpenAccess fees, allowing your research to be published and shared freely at no cost 🌍 Visit our website for more information 👇

📢 Call for Papers📢 Seeking research, reviews and perspectives on structural biology, protein dynamics, biomarkers, pharmacogenomics, multi-omics integration and precision therapeutics. 🗓️ Submit by 31 Dec 2026 for free #OpenAcess publication! 🔗 www.sciencedirect.com/special-issu...

We're delighted to consider your papers! We are nearing the end of the free open access period! Submit soon for no cost publishing!

The Journal of Precision Medicine: Health and Disease@jprecmed.bsky.social · 3w ago

Free Open Access Publication: Limited time offer ⏰ Submit your work by 31 December 2026 to enjoy fully waived #OpenAccess fees, allowing your research to be published and shared freely at no cost 🌍 Visit our website for more information 👇

Colleagues, Since the launch of The Journal of Precision Medicine: Health and Disease, papers are flowing in and we're ready to expand the editorial board! Nominate a colleague or self-nominate! An exciting opportunity to shape precision medicine, get editorial experience and host special issues!

The Journal of Precision Medicine: Health and Disease@jprecmed.bsky.social · 4w ago

Join our Editorial Board! 🎓️ We’re inviting nominations for new Editorial Board members to help shape the future of precision medicine. Self-nominations are warmly welcomed. Submit a statement of interest, CV and short biography to jpm@physoc.org by 30 November 2026.

So excited to serve as a Guest Editor w/ Professors Koichi Nakajo and Bikash Pattnaik for the upcoming special issue: @JPrecisionMed “Ion Channels in Precision Medicine: Mechanisms, Modeling and Therapeutic Innovation”

We are looking forward to your submissions! Reach out with a presubmission inquiry if you need more information!

The Journal of Precision Medicine: Health and Disease@jprecmed.bsky.social · 3mo ago

📣Call for Papers: Ion Channels in Precision Medicine 🧑‍⚕️ Guest Editors: Koichi Nakajo, Bikash R. Pattnaik, and Colleen E. Clancy 📅 Deadline: 31 December 2026 👇️ More information: www.jprecisionmedicine.org/call-for-pap...

CPMDS Research Highlight 🔬 CATVariant is a new open-access webserver for studying genetic variants, integrating population, clinical, structural, and literature data with computational predictors to help interpret variant effects. Read more: doi.org/10.1093/nar/... | Explore: catvariant.com

Maxime Lammens, Frank Bosmans et al. show how an auxiliary β1 subunit tunes the activity of the human Na+ channel NaV1.6, a key regulator of electrical signaling in neurons, linking channel structure to mechanisms that shape neuronal excitability. rupress.org/jgp/article/... #IonChannels

CPMDS Research Highlight 🔬 Computational models reveal how the autonomic nervous system regulates blood flow and blood pressure across molecular, cellular, and tissue scales, providing insights that could guide future precision cardiovascular therapies.

Smooth signals: computational insights into autonomic vascular control | American Journal of Physiology-Cell Physiology | American Physiological Society

The regulation of vascular tone underlies normal cardiovascular homeostasis, ensuring appropriate distribution of blood flow to tissues and maintenance of blood pressure. Computational modeling and si...

journals.physiology.org

New publication in Nucleic Acids Research describing CATVariant, an open-access web server for integrated protein variant interpretation. 🔗 Read the paper: doi.org/10.1093/nar/... 🌐 Try CATVariant: catvariant.com #Bioinformatics #PrecisionMedicine #Genomics #ProteinVariants #NAR #OpenScience

CATVariant: a web server for integrated protein variant interpretation across sequence, structure, population, and clinical evidence

Abstract. Efficient interpretation of the structural, functional, and clinical impact of protein variants remains a longstanding challenge. This difficulty

doi.org

@ucdcpmds.bsky.social · 4mo ago

CPMDS Research Highlight 🔬 CATVariant is a new open-access webserver for studying genetic variants, integrating population, clinical, structural, and literature data with computational predictors to help interpret variant effects. Read more: doi.org/10.1093/nar/... | Explore: catvariant.com

We're at #ICMSTokyo! 🔬 🗾 Koichi Nakajo, Reviewing Editor for the journal, is here to share more information about our mission linked to innovative strategies for ion channel research and drug development 💉 🥼 Kazuharu Furutani is pictured here with the journal's front cover! 📷

CPMDS Research Highlight 🔬 (Drs. Igor Vorobyov, Vladimir Yarov Yarovoy, Colleen E. Clancy) Researchers used advanced simulations to reveal how ligands dissociate from membrane receptors, uncovering hidden molecular pathways that could improve drug discovery and precision therapeutics. 💻

New research shows how AlphaFold can predict hERG ion channel states, improving drug safety screening and helping identify arrhythmia risks earlier in drug development. A major step toward safer, AI-driven therapeutics. #AI #DrugDiscovery Read more here: pmc.ncbi.nlm.nih.gov/articles/PMC...

Harnessing AlphaFold to reveal hERG channel conformational state secrets

To design safe, selective, and effective new therapies, there must be a deep understanding of the structure and function of the drug target. One of the most difficult problems to solve has been the re...

pmc.ncbi.nlm.nih.gov

🔬 CPMDS Research Highlight New research highlights how AI and digital health technologies are improving healthcare quality and patient safety through proactive, data-driven care, clinical decision support, telehealth, and better care coordination. #DigitalHealth pubmed.ncbi.nlm.nih.gov/40752934/

Health Care Quality and Patient Safety in the Era of Artificial Intelligence - PubMed

The integration of digital health technologies is revolutionizing health care quality and patient safety by shifting from reactive to proactive care models. Advances in electronic health records, clin...

pubmed.ncbi.nlm.nih.gov

🔬CPMDS Research Spotlight New research highlights how advances in cardiovascular ion channel and Ca²⁺ signaling research are shaping future therapies for heart disease, including arrhythmias and heart failure. ❤️🫀 Read more: pubmed.ncbi.nlm.nih.gov/41605640/

Associate Director for Computational Biomedicine Dr. Emilie Roncali recently gave a keynote on theranostics digital twins and in silico models at the Virtual Imaging Trials in Medicine workshop 2026!!

🔬 CPMDS Research Spotlight (Dr. Emilie Roncali): CFD is advancing cancer therapy by modeling blood flow & drug transport to improve targeting and reduce side effects. Integrating with imaging & AI could enable more personalized treatment. lnkd.in/deHn6Pp4 #CancerResearch #PrecisionMedicine

📣CALL FOR PAPERS📣 Organised and edited by @clancyatheart.bsky.social This Special Issue welcomes original research articles, reviews and perspectives that explore the intersection of New Approach Methodologies (#NAMs) with #precisionmedicine 🧬 📍 🔗 For more information👇️ buff.ly/lFDfYnV

Congrats to Frederick Ha who presented his research at the Undergraduate Research, Scholarship and Creative Activities Conference at UC Davis! Image Description: Frederick stands at the front of a classroom giving a presentation.

CPDMS Research Spotlight (Dr. Deborah Lieu): New research in Stem Cell Reports reveals insights into how cellular programs regulate stem cell behavior, deepening our understanding of development and advancing potential applications in tissue repair and disease modeling www.cell.com/stem-cell-re...

A humanized engineered heart tissue platform for cardiotoxicity assessment

In this article, Sun and colleagues develop a humanized engineered heart tissue platform by integrating human ventricular extracellular matrix with GCaMP6f-expressing hiPSC-derived cardiomyocytes. Thi...

cell.com

In this new #Review, Chiara Anna Giordani (@ucdcpmds.bsky.social) and @clancyatheart.bsky.social discuss #dose as a fundamental organizing principle in physiology. 💉 💊 🔗 Read it here: www.sciencedirect.com/science/arti...

Congratulations to Dr. Fred Meyers on receiving the 2026 ACTS Distinguished Educator: Mentorship Innovation Award! This honor recognizes innovative mentorship advancing translational science and supporting diverse researchers. Proud to celebrate this achievement! 🎉

New research shows common therapies, estrogen, metformin, statins, and vitamin D, may unintentionally affect regulatory T cells (Tregs), key to immune balance. Understanding these effects could help advance more precise, personalized care. pubmed.ncbi.nlm.nih.gov/41855744/

Deep Learning Echocardiographic Trajectories of Heart Failure With Preserved Ejection Fraction: A Retrospective Cohort Study - PubMed

Longitudinal phenomapping resulted in echocardiographic trajectories of cardiac structure and function with different clinical, laboratory, and survival characteristics. HFpEF is a dynamic condition, ...

pubmed.ncbi.nlm.nih.gov

🔬 Ionizing radiation reshapes heart cell function—not just tissue damage. Low–moderate doses: pro-arrhythmic High doses: improved electrical stability 🧠 Mitochondria drive these effects 💡 May help optimize radiotherapy & reduce cardiac risk 📖 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

Abstract figure legend Dose-dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate ....

physoc.onlinelibrary.wiley.com

Jan 14, 2026: The Data Science Seminar Series spotlighted theranostics & digital twins in cancer care. Emilie Roncali shared advances in liver, prostate & metastatic cancers improving diagnosis, treatment & outcomes. www.cancer.gov/about-nci/or... #CancerResearch #DigitalTwin #PrecisionMedicine

Theranostics and Digital Twins for Personalized Medicine

On January 14, the Data Science Seminar Series is tackling an intersection of two critical data science concepts in cancer research: theranostics and digital twins. By combining computational and clin...

cancer.gov