Unifying Repbase and Dfam: a new open foundation for transposable element research - Mobile DNA

Repbase and Dfam, the two foundational resources for transposable element annotation, are being unified into a single, fully open access framework, with Repbase released under CC-0 and its core curati...

link.springer.com

The Feschotte Lab at Cornell

thefeschottelabatcornell.com

Compbio Asia

compbioasia.net

ColabCuraTE: an easy-to-use, web-based pipeline for the manual curation of transposable elements - Mobile DNA

Background Transposable elements (TEs) are widespread mobile DNA sequences that shape genome structure, function, and evolution. Although automated tools exist for the de novo identification and class...

link.springer.com

Transposable elements drive much of naturally occurring genetic lethality in Drosophila melanogaster

Recessive lethal mutations are widespread across studied species, with estimates suggesting that each individual carries at least one. Numerous lethal alleles persist in wild populations at higher fre...

biorxiv.org

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation

Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

cell.com

Rapid emergence of non-autonomous elements may stop P-element invasions in the absence of a piRNA-based host defence

Author summary Transposable elements (TEs) are short, self-replicating DNA sequences found in nearly all genomes. While they can be harmful to their hosts, many organisms have evolved defence systems,...

journals.plos.org

A Concise Guide for the Characterization and Curation of Transposable Elements in Insect Genomes

Transposable elements (TEs) can play a huge role in shaping the structure and evolution of genes and genomes, but it can be difficult, especially in non-model organisms, to confidently characterize th...

link.springer.com

Adaptive P-element insertions in a long non-coding RNA are associated with unique silencing properties

Transposable elements are genetic parasites whose mobilization throughout the genome is a major source of deleterious mutations. However, some TE insertions are beneficial because they improve host fi...

biorxiv.org

A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage

A phylogenetic approach reveals cryptic LTR subfamilies and functional insights at nucleotide resolution in primates.

science.org

No evidence of transposable element bursts in the Galápagos Scalesia adaptive radiation despite hybridization, diversification and ecological niche shifts - Mobile DNA

Transposable elements (TEs) have been hypothesized to play a pivotal role in driving diversification by facilitating the emergence of novel phenotypes and the accumulation of divergence between specie...

mobilednajournal.biomedcentral.com

GitHub - zeqianli/tgv: Explore 5,000+ genomes in the terminal. Light, blazing fast 🚀, vim-motion.

Explore 5,000+ genomes in the terminal. Light, blazing fast 🚀, vim-motion. - zeqianli/tgv

github.com

Genomic and genetic insights into Mendel’s pea genes - Nature

Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their m...

nature.com

biorxiv.org

Celebrating DNA Day with transposable elements

Each year on DNA Day, we celebrate the DNA double helix structure and the Human Genome Project's completion. Here we dive into a fascinating genomic component: transposable elements. Once seen as mere...

go.nature.com

Column | Delete your DNA from 23andMe right now

The genetic information company declared bankruptcy on Sunday, and California’s attorney general has issued a privacy “consumer alert.”

washingtonpost.com

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

pnas.org

Rapid emergence of hyperparasitic elements may stop P-element invasions in the absence of a piRNA-based host defence

Transposable element (TE) invasions pose risks to both the TE and the host. All copies of a TE may be lost via genetic drift, or host populations may suffer fitness declines, potentially leading to ex...

biorxiv.org

biorxiv.org

LOCATE: using Long-read to Characterize All Transposable Elements

Transposons constitute ~45% of the human genome, driving gene evolution and contributing to disease, but their repetitive nature complicates the identification of new insertions. We present LOCATE (Lo...

doi.org

biorxiv.org

Crosstalk between RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells - Nature Genetics

The N6-methyladenosine reader YTHDC2 recruits TET1 to remove 5-methylcytosine from LTR7/HERV-H loci in human embryonic stem cells. The YTHDC2/LTR7 pathway inhibits neural fate commitment.

nature.com

Pannagram: unbiased pangenome alignment and the Mobilome calling

Pannagram is a toolkit for unbiased pangenome alignment and Mobilome detection based on full-genome assemblies. It consists of two components: a command-line interface for performing the multiple geno...

biorxiv.org

Exploring the role of transposable elements to sex gap in longevity in Drosophila species

In Drosophila, like in many other animal species, females tend to live longer than males, a phenomenon known as sex gap in longevity (SGL). One of the possible causes underlying this phenomenon could ...

biorxiv.org