Using calcium imaging in macaque PFC during a meta–WM task, we show that PFC jointly encodes remembered locations + uncertainty. PFC integrates WM strength + cues into a meta-WM signal that guides behavior. A collab btw our team and Liping Wang group doi.org/10.1016/j.ne... 🧠🟦🧠🤖
the computational brain lab
@computationalbrain.bsky.social
https://computationalbrainteam.com
Using 7T fMRI, our team found a representation of the probability of the next event in human dlPFC —and it’s highly non-monotonic. Confidence signals, in contrast, were mostly monotonic. doi.org/10.1038/s414... 🧠🟦🧠🤖
Thank you Nicole! Nicole's wonderful book 'Elusive Cures' has played an important role in pushing me out of my comfort zone and join forces w/ @philippedomenech.bsky.social and @bellecguill.bsky.social, here. Exciting times ahead for neuroscience. Go read it, if you haven't yet!
Exciting! A project that taps into the genius of this era on multiple levels - dynamical systems, machine learning / RL, brain computer interfaces in a terrific group. And bonus: it's in Paris 💙.
Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻 Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems. See below for + details and retweet 🙏
🚨 !!! New preprint !!! 🚨 MULTIMODHAL (phase 3, multicenter double-blind RCT): fMRI “symptom-capture”–guided neuronavigation significantly improves 1-Hz rTMS outcomes for drug-resistant auditory verbal hallucinations vs standard T3P3 targeting. 🧠🟦 #rTMS #Psychiatry #Schizophrenia #fMRI
medrxiv.org
Researchers in France are working on creating a french network of researchers to organize interaction, communication and training in #Computational_Neuroscience. If you are a CompNeuro working in France, consider joining, and registering to our mailing list: listes.services.cnrs.fr/wws/subscrib...
rt_neurocomp - réseau français de neurosciences computationnelles - subscribe
listes.services.cnrs.fr
"Polygenic scores for complex human behavior don’t work" ericturkheimer.substack.com/p/is-tan-et-...
Is Tan et al. The End of Social Science Genomics?
What happens when everything is unconfounded?
ericturkheimer.substack.com
Excited to share our preprint: "Recasting adaptation as strategy inference". This work explores how humans spontaneously adapt to changes by inferring strategies, rather than relying on incremental learning.@philippedomenech.bsky.social @khamascience.bsky.social @computationalbrain.bsky.social 🧠🟦 🧠🤖
Recasting adaptation as strategy inference
Flexible adaptation to uncertain and changing environments requires dynamic adjustments in behavioral strategies. While classical learning theories emphasize incremental strengthening of local stimulu...
tinyurl.com
This guy is speaking at 'legendary Piano Vache bar 🍺' this Friday at 5pm (one free drink included!)
Come hang out with the Parisian neuroscience community this Friday (and once a month!) at the legendary Piano Vache bar 🍺
The massive changes in US research brought about by the new administration of President Donald Trump are causing many scientists in the country to rethink their lives and careers https://go.nature.com/41OhAgK
75% of US scientists who answered Nature poll consider leaving
More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.
go.nature.com
The unparalleled XJ Wang has written a book about the computations underlying cognition. I read a draft version and it is awesome. He is not on social media, so I am sharing it on his behalf :)
Recasting adaptation as strategy inference https://www.biorxiv.org/content/10.1101/2025.03.24.645064v1
Too much or not enough? Optimal level of human intracranial theta activity for rule-switching in the subthalamo-medio-prefrontal circuit. 🧠🟦 🧠🤖 www.biorxiv.org/content/10.1...
Are you a (computational) neuroscientist looking for a postdoc? Come to Paris! There are plenty of great labs always looking for talent, including our own