🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...

Congratulations Isa! Great to see your paper out 🎉

@isabellavoelkl.bsky.social · 9mo ago

Thrilled to share that my PhD work is now published! 🧬 “In vitro approaches to study centriole and cilium function in early mouse embryogenesis” uncovers how these tiny organelles influence early cell organization and tissue patterning in 3D models. www.life-science-alliance.org/content/9/1/...

I’m deeply grateful to my supervisor @chribue.bsky.social, Alexander Dammermann, Martin Leeb and all colleagues and collaborators for their support throughout this journey. Thank you @vbcscitraining.bsky.social and @maxperutzlabs.ac.at for providing such a stimulating scientific environment.

Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.

In vitro approaches to study centriole and cilium function in early mouse embryogenesis

Although centrioles and primary cilia play an essential role in early mammalian development, their specific function during the interval between their initial formation and the subsequent arrest of em...

life-science-alliance.org

This whole line of research was driven by @isabellavoelkl.bsky.social and is a deviation from my expertise. Without the help of @dammermannlab.bsky.social, we would have been lost on the way. So grateful for my amazing colleagues at the @maxperutzlabs.ac.at

Schreiner, Mikeladze-Dvali et al. @lifescimunich.bsky.social show that CDK-1 primes PCMD-1 for PLK-1 phosphorylation. Mutations in PLK-1 docking sites impair SPD-5 binding, destabilize the PCM, and delay #centriole separation. rupress.org/jcb/article/... #Centrosome #PCMstability #Celegans

Centrosomes might look tough, but they are actually big softies - see the latest work from the Dammermann lab now on BioRxiv:

Júlia Garcia-Baucells@jugarbau.bsky.social · 11mo ago


1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.

See also:

arXiv physics.bio-ph Biological Physics@physicsbioph-bot.bsky.social · last yr.

Oliver W. Paulin, J\'ulia Garcia-Baucells, Luise Zieger, Sebastian Aland, Alexander Dammermann, David Zwicker: Active viscoelastic condensates provide controllable mechanical anchor points https://arxiv.org/abs/2506.14591 https://arxiv.org/pdf/2506.14591 https://arxiv.org/html/2506.14591

🆕 publication! What do centriolar satellites really do? In @jcb.org the Dammermann lab challenges the idea that they simply shuttle proteins to the centrosome and cilium. Instead, their findings reveal a surprising new role linked to translation and protein quality control. More tinyurl.com/4dnb2c24

Pachinger, Dammermann et al. @maxperutzlabs.bsky.social‬ present a model for centriolar satellites not as transport modules but as sites of translation specifically of centrosomal and ciliary proteins. rupress.org/jcb/article/... #centrosomes #cilia

Hello and welcome everyone to our new Dammermann Lab Bluesky account 😊 Since leaving X in January, a lot has happened: