Defne Bayik
@dbayik.bsky.social
Assist Prof at @univmiami and @SylvesterCancer studying #glioblastoma #immunotherapy. #WomenInSTEM #NewPI @theNCI and @CCLRI alum. Opinions mine. she/her
A few of my colleagues and I hosted an event, Science on Tap, aimed at fostering relationships between scientists and local community members. In the blog, I talk about why I think these kind of events are important and how it went! medium.com/science-poli...
Science on Tap🍻: Serving up Science to Community Members in Miami
Written by SNAP member Brandon Emanuel León
medium.com
Thank you very much for highlighting our publication and supporting our work! #cancer #immunotherapy #glioblastoma #immunometabolism #MDSC
American Cancer Society@americancancersoc.bsky.social · 2mo ago1. New findings in @natcancer.nature.com from senior author @dbayik.bsky.social that highlight the sex-specific immunomodulatory role of GABA in tumorigenesis. ACS supported this work via Dr. Sravya Palavalasa's postdoctoral fellowship. Dr. Bayik is past IRG subawardee. doi.org/10.1038/s430...
1. New findings in @natcancer.nature.com from senior author @dbayik.bsky.social that highlight the sex-specific immunomodulatory role of GABA in tumorigenesis. ACS supported this work via Dr. Sravya Palavalasa's postdoctoral fellowship. Dr. Bayik is past IRG subawardee. doi.org/10.1038/s430...
GABA signaling activation drives glioblastoma progression in female mice through myeloid-derived suppressor cells - Nature Cancer
Pathak et al. unveil a female vulnerability for glioblastoma according to a mechanism that relies on γ-aminobutyric acid receptor-mediated signaling on granulocytic myeloid-derived suppressor cells, w...
doi.org
📣 Check out our new research @natcancer.nature.com! There is more to sex differences in cancer immune responses than sex chromosomes and hormones. We found that neurotransmitter signaling differentially shapes myeloid cell metabolism in glioblastoma: www.nature.com/articles/s43...
GABA signaling activation drives glioblastoma progression in female mice through myeloid-derived suppressor cells - Nature Cancer
Pathak et al. unveil a female vulnerability for glioblastoma according to a mechanism that relies on γ-aminobutyric acid receptor-mediated signaling on granulocytic myeloid-derived suppressor cells, w...
nature.com
GABAB signaling enhances immunosuppressive programs of myeloid-derived suppressor cells in female models of preclinical glioblastoma @natcancer.nature.com @dbayik.bsky.social @univmiami.bsky.social www.nature.com/articles/s43... www.nature.com/articles/s43...
So proud of my graduate student @brandonleon95.bsky.social for discussing the importance of science funding for our community! medium.com/scitech-fore...
Why Investing in Science Is a Lifesaving Choice for Miami
Growing up in the shadows of the National Institutes of Health (NIH), I’ve always been inspired by the leaps in medical research.
medium.com
Exceptional #SNO2025 talk from UM MSTP student @j-mitchell.bsky.social on the role of mitochondria transfer in GBM! Proud PI moment w/ @dionysioswatson.bsky.social 💪🏻
🚨 Attention immunologists 💉: We are seeking a postdoctoral fellow to lead projects on tumor-targeted cytokines and bacterial extracellular vesicles for cancer immunotherapy (focus - brain and lung cancers). 😎 🏖️ University of Miami www.DiscoverTME.com . Please DM if interested.
DiscoverTME lab | Therapeutics targeting tumor microenvironment interactions
DiscoverTME is a biomedical research laboratory at Sylvester Comprehensive Cancer Center, University of Miami, FL
discovertme.com
few outcomes, except for 99% of FDA-approved drugs, 174 recipients of 104 Nobel Prizes, training ~30K MDs and ~10K PhDs per year to enter the workforce, and a 34% reduction in age-adjusted cancer deaths since 1990 -- the largest decrease in history
Drug Monkey@drugmonkey.bsky.social · last yr.Now do the Department of Defense budget, Andrew. “Washington has thrown billions at NIH for decades with little accountability and few measurable outcomes,” HHS spokesperson Andrew Nixon said in a statement to Future Pulse. www.politico.com/newsletters/...
73% of mothers with kids under 18 are in the workforce. More than flowers or brunch, working moms need: -Paid family leave -Equal pay -Universal childcare (But get your mom flowers, too)
1/3 PLEASE READ, LIKE, REPOST this "1/3" post There is a Senate Hearing May 14th with RFK Jr to discuss Trump's proposed HHS budget. Please find call/email the members of the committee every day until then (I have compiled contact info for the members in post 2/3)
Lookin for a good read in between experiments? Check out the commentary article in @neuroonc.bsky.social @dbayik.bsky.social and I wrote on an insightful study on myeloid cells in gliomas 🙂↔️ link here: academic.oup.com/neuro-oncolo...
An in-depth survey of immunosuppressive myeloid cell heterogeneity in GBM
Brandon Emanuel León, Defne Bayik; An in-depth survey of immunosuppressive myeloid cell heterogeneity in GBM, Neuro-Oncology, , noaf080, https://doi.org/10
academic.oup.com
The information I am receiving is consistent with the STAT story. The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women. 3/n
Today, a broad coalition of scientific professional societies who represent over 92,000 scientists are speaking out against the politicization and demonization of Federally funded science and government scientist jobs. It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
48 Scientific Societies Representing Almost 100,000 Scientists Ask Congress to Protect the Future of Science
48 scientific societies representing almost 100,000 scientists signed on to a letter asking Congress to protect the future of science
ucsusa.org
Richest guy in the world telling us we can’t afford to have our government fund cancer research.
Taking a cue from @cantlonlab.bsky.social, I have written an op-ed for my local newspaper about the impact of the NIH funding chaos. I'd appreciate it if you read and share. #NIH #Research #Science #Worcester www.telegram.com/story/opinio...
Opinion/Guest column: Gutting NIH a disaster in the marking for research, local economy
Less research equates to less business between the university and these Worcester companies, spreading the pain far beyond campus borders.
telegram.com
Today, the study section I am a member of is one of 26 out of 26 canceled. No new post on the federal registry and councils are postponed indefinitely. Universities focused on overhead cuts considering these a challenge to their survival. But *no grant at all* seems like the issue to battle first..
Soragni:Lab@alice.soragnilab.com · 2y agoThe NIH continues to be fully halted. 11/11 study sections canceled today, which includes the study section my grant was meant to be reviewed at. This is never ending and so damaging. www.csr.nih.gov/RevPanelsAnd...
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
NIH funding freeze stalls applications on $1.5 billion in medical research funds
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
npr.org
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. https://go.nature.com/4gM6oW4
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
go.nature.com
NEW: The Trump administration is exploiting a loophole to keep funding frozen at the NIH - a move that some legal scholars say is illegal. Federal Register notices are blocked, so no grant-review sessions can be scheduled. All the gritty details here, and a short 🧵: www.nature.com/articles/d41...
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
nature.com
I do not understand how sex can be binary and immutable and fundamental and you're stuck with the one you were born with, but also not a variable worth studying. I... just... one hand argues men and women are fundamentally different and the other says but we don't care?
41/47 (87%) of NIH study sections are cancelled this week Frustrating to see all this good research stalled (& not funded) You can search for study sections that ‘did not meet as scheduled’ here with ones with * ⤵️ www.csr.nih.gov/RevPanelsAnd...
Review Dates
csr.nih.gov
I just covered this for @thetransmitter.bsky.social — will keep following! www.thetransmitter.org/funding/fede...
Federal Register hold makes ‘end run’ around court pause on NIH funding freeze
NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...
thetransmitter.org
I have not seen a crisis of this magnitude since yesterday
Congratulations @brandonleon95.bsky.social for getting selected to represent University of Miami Miller School of Medicine at the 2025 CASE Workshop organized by AAAS! Can't wait to see what you will achieve in #SciPol #MakingOurCASE 💪
With 25 days to go, please consider supporting our efforts to fund cancer research 👇 dolphinscancerchallenge.com/participant/...
Help me Challenge Cancer!
The DCC is a year-round collective community movement to raise money in support of Sylvester Comprehensive Cancer Center at the University of Miami. With your support, we are saving more lives. #OneTe...
dolphinscancerchallenge.com
