New #OpenAccess summary of microclots in #LongCOVID with @resiapretorius.bsky.social: Grixti, J. M., Pretorius, E., Kell, D. B. (2026) Uncovering the hidden biology of fibrinaloid microclot complexes in complex, inflammatory diseases. QRB Discovery. 7, e9. doi.org/10.1017/qrd.... #TeamClots

Uncovering the hidden biology of fibrinaloid microclot complexes in complex, inflammatory diseases | QRB Discovery | Cambridge Core

Uncovering the hidden biology of fibrinaloid microclot complexes in complex, inflammatory diseases - Volume 7

doi.org

In the latest issue of ‪Analyst: Rapid antimicrobial susceptibility testing in bloodstream infections: current landscape and emerging technologies. #OpenAccess from Douglas B. Kell et al @dbkell.bsky.social @livuni-ismib.bsky.social Read now: pubs.rsc.org/an/article/d...

New paper with @resiapretorius.bsky.social et al #TeamClots Roberts, I., Tan, X., Moore, J. B., Pretorius, E. and Kell, D. B. (2026) Bioinformatic assessment of the potential amyloidogenicity of the human and evolutionarily more ancient proteomes. Biochem J. 483, 1337-1355. doi.org/10.1042/BCJ2...

New #OpenAccess review on yeast transporters published www.tandfonline.com/doi/full/10.... @livuni-ismib.bsky.social

Advances, challenges, and opportunities in engineering C5 and C6 sugar transporters in yeast for bio-based industrial biotechnology

Harnessing biomass for bio-based industrial biotechnology is vital for addressing global energy needs and mitigating climate change. In this context, microorganisms are the cornerstone of biorefine...

tandfonline.com

Our review of antimicrobial susceptibility testing is out pubs.rsc.org/en/content/a... @livuni-ismib.bsky.social

Rapid antimicrobial susceptibility testing in bloodstream infections: current landscape and emerging technologies

Rapid bloodstream infection diagnosis is essential to enable timely targeted therapy, to reduce the risk of progression to sepsis, to limit unnecessary antimicrobial exposure, and to support effective...

pubs.rsc.org

Celebrating 120 years of the Biochemical Journal, we're hosting a special free webinar on 17 June where @dbkell.bsky.social will be exploring how fibrinaloid microclots affect the microcirculation, and the effects on chronic inflammatory diseases. Register now 🧪 bit.ly/3S1m6pC

Gearing up for @foundscitech.bsky.social chat between Lord Willetts and Sir Ian Chapman (UKRI boss).

If folk are interested, I am giving a @BiochemSoc talk on our work with @resiapretorius.bsky.social on Fibrinaloid Microclot Complexes in Long Covid and ME/CFS on June 17 at 2pm. Registration needed but free register.gotowebinar.com/register/226... #TeamClots #pwLC #pwME

A SECOND review with @resiapretorius.bsky.social also published today Kell, D. B. and Pretorius, E. (2026) Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging. J Biophotonics. 19, e70270. doi.org/10.1002/jbio... #TeamClots @livuni-ismib.bsky.social

Assessing the Health and Functionality of the Microcirculation Using Thermal Imaging

We review the techniques of thermal imaging for assessing the functional consequences of lowered blood flow in the microcirculation that accompanies many chronic, inflammatory diseases. A comparison ...

doi.org

New review with @resiapretorius.bsky.social Kell, D. B., Zhao, H. and Pretorius, E. (2026) Fibrinaloid Microclots-Induced Microcirculation Dysfunction: Mechanism and Laser-Based Haemodynamic Validation. Cardiovasc Sci. 3, 10005. doi.org/10.70322/cvs... #TeamClots @livuni-ismib.bsky.social

Fibrinaloid Microclots-Induced Microcirculation Dysfunction: Mechanism and Laser-Based Haemodynamic Validation

The microcirculation typically refers to those capillaries less than 100 μm in diameter. We have shown that blood can clot into an anomalous amyloid form, manifesting as microclots of typically 2–200 ...

doi.org

New review: Kell, D. B. and Roberts, I. (2026) How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution. Chem Soc Rev, in press. doi.org/10.1039/d5cs... @livuni-ismib.bsky.social

How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution

The number of possible variants representing the landscape of a protein sequence of length N residues, made of the standard unmodified proteinogenic amino acids, is 20N; its exhaustive experimental an...

doi.org

From dirt to discovery! In our latest blog, Dr Rachel Floyd and Dr Amy Wedley discuss how research-connected teaching can build the skills, confidence and scientific curiosity the next generation of bioscientists need. 🔗 bit.ly/43avzwV #TeamLivUni

I love that the paper mentions PPAR agonists! Maybe we'll hear more at Roundtable with @dbkell.bsky.social & @resiapretorius.bsky.social (+ Dr. Vaughn + Dr. Schofield) + some very awesome panelists. Fri MAR 13 1 pm EDT US by @renegaderesearch.bsky.social us06web.zoom.us/webinar/regi...

Sign up for the free Research Roundtable on Hypercoagulability, Clotting and Microclotting, and Blood Issues in MECFS and Long Covid. Speakers: Resia Pretorius, Douglas Kell, Jordan Vaughn, Jill Schof...

A panel of clinicians and researchers will speak, followed by a Q&A and discussion. Your panel: Resia Pretorius, PhD - resiapretorius.net Distinguished Research Prof. of Physiological Sciences Ste...

us06web.zoom.us

valebodi.bsky.social@valebodi.bsky.social · last yr.

One year ago this excellent paper was published Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: the biology of a neglected disease Hayley E. Arron, Benjamin D. Marsh, Douglas B. Kell, M. Asad Khan and Etheresia Pretorius www.frontiersin.org/journals/imm... #ME/CFS @resiapretorius.bsky.social

What great presentations and illustrative slides. What a valuable discussion! Thank you to panelists @resiapretorius.bsky.social @dbkell.bsky.social Jordan Vaughn and Jill Schofield. We'll post recording link soon. We were about to wrap at 2 hr 50 min when webinar accidentally ended. Sorry.

Renegade Research@renegaderesearch.bsky.social · 5mo ago

Join us March 13 at 1 pm ET (US) for a Research Roundtable with @resiapretorius.bsky.social of @suhealthsci.bsky.social @liverpooluni.bsky.social, @dbkell.bsky.social of @liverpooluni.bsky.social, Jordan Vaughn of MedHelp, Jill Schofield of @cuanschutz.bsky.social 🧵Registration link, research below

March 13 at 1 pm ET (US) for a Research Roundtable with @resiapretorius.bsky.social of @livunipress.bsky.social @dbkell.bsky.social @jfvaughnmd09 discussing: Hypercoagulability, Clotting and Microclotting, and Blood Issues in ME/CFS and Long Covid 👇 youtu.be/FygtEROEqXE?...

Research & Clinician's roundtable on Hypercoagulability, and Blood Issues in MECFS and Long Covid

YouTube video by Renegade Research

youtu.be

What great presentations, illustrative slides, and a valuable discussion! Thanks to our panelists @resiapretorius.bsky.social @dbkell.bsky.social and Drs. Jordan Vaughn and Jill Schofield Thanks to our audience for your questions! The link to the YouTube recording is in the final post on this 🧵⬇️

Renegade Research@renegaderesearch.bsky.social · 5mo ago

Join us March 13 at 1 pm ET (US) for a Research Roundtable with @resiapretorius.bsky.social of @suhealthsci.bsky.social @liverpooluni.bsky.social, @dbkell.bsky.social of @liverpooluni.bsky.social, Jordan Vaughn of MedHelp, Jill Schofield of @cuanschutz.bsky.social 🧵Registration link, research below

mastodon.social/@We_Own_It/1...

10/ This comprehensive study of treatment outcomes in 3,925 patients with #ME/CFS & #LongCOVID, examined over 150 supplements, #OTC medications, prescription medications - www.pnas.org/doi/10.1073/...

8/ "In the early era of HIV, we tried single-drug therapies, but nothing worked. Two drugs, that didn’t really work. Three drugs – boom": www.ucsf.edu/news/2026/01...

Solving Long COVID: How Decades of HIV Research Paved the Way

Discover how UCSF is leading the charge in Long COVID research, uncovering key findings that advance our understanding of the condition. UCSF researchers have adapted innovative tools and methodologie...

ucsf.edu

7/ Pay attention to this - ⚠️ "...there's going to be a number of Trials done on single drug therapy and they will fail I can predict it now..." #DrJacoLaubscher

4/ "How soon do most people notice benefits from proteolytic enzymes? The vast majority (3/4) reported benefits in under 2 weeks, and 42% noticed benefits within just 1 week": open.substack.com/pub/pharmd/p...

TREAT ME Survey: Individual Treatment Results

Proteolytic Enzymes (Nattokinase, Lumbrokinase, Serrapeptase)

open.substack.com

1/ I rarely repost any advice on apparent silver bullets for #LongCOVID, because I don't want to raise false hope. However, I make any exception for the #Microclot hypothesis. Anecdotally, it appeared to significantly help my son & I - @resiapretorius.bsky.social @dbkell.bsky.social

There's no ICE accountability without ending qualified immunity. They're murdering people. There won't be justice for the lives they've stolen, but there must be accountability. My bill with @markey.senate.gov would ensure families can sue the agents murdering their loved ones.

BREAKING: Two Republican senators, Thom Tillis and Lisa Murkowski, call for DHS Secretary Kristi Noem to resign.

Two Republican senators call for Kristi Noem to resign as DHS secretary

Sens. Lisa Murkowski and Thom Tillis are the first GOP members of Congress to call for Noem to step down as secretary of the Department of Homeland Security.

nbcnews.com

Writing with @rupertread.bsky.social about just how devastating the Government- suppressed security report is, particularly its conclusions about our food insecurity. Ministers should be helping to build our resilience to these threats, not burying the report that contains them 👇

It's ecological breakdown that should put us on a war-footing: official

Admissions of extreme, eco-caused national security threats foreground importance of climate adaptation to bring much needed urgency and agency.

resilience.org

Ongoing genocide by terrorist russia. 🤬

Tim White@twmcltd.bsky.social · 6mo ago

Russia is clearly committing genocide. Trying to freeze the people into submission is a clear breach of one Geneva convention. Now bombing passenger trains is, as Zelenskyy says here, just brushed off. It was 5th story on a BBC radio bulletin an hour ago.

Amid growing calls for the abolition of ICE, Rep. Delia Ramirez is calling for the entire DHS to be dismantled. Highlighting how much experience the officers who killed Renee Good and Alex Pretti had, Ramirez said, “DHS was built to violate our rights and has been empowered to act with impunity.”

House Democrat Says Abolishing ICE Isn’t Enough — DHS Must Go, Too

“The problem isn’t ‘training.’ DHS was built to violate our rights,” said Rep. Delia C. Ramirez.

truthout.org

20/ Next, I tried the same regimen on my then 23-year old son. And within weeks he noticed an improvement in multiple, unexplained severe pains in internal organs, & an amelioration of some of his #LongCOVID symptoms. More resources here, courtesy of @dbkell.bsky.social - dbkgroup.org/longcovid/

13/ I can't tell you how many times I have spelled this word for health providers who feign mild interest but somehow never get around to looking it up. "But what exactly is #Nattokinase, and why does it work?": @resiapretorius.bsky.social @dbkell.bsky.social youtu.be/6q2WS4NuiBQ?...

Can Nattokinase Help Break Down 'Microclots'? | With Prof Resia Pretorius & Prof Doug Kell

YouTube video by Gez Medinger

youtu.be

Massimo Nunes, Loren Kell, Anouk Slaghekke, Rob CI Wüst, Burtram C. Fielding, Douglas B. Kell & Etheresia Pretorius @resiapretorius.bsky.social @dbkell.bsky.social et al.