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Research Support Officer | Cell Biology | Dr Buzz Baum | LMB 2904 at MRC Laboratory of Molecular Biology

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We wrote a method paper on our different microfluidic technologies to confine microbial cells, and display a novel and unique device to confine and even retrieve cells to perform, for instance, omics analysis on confined cells! Reach out if this is of interest for your research.

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 4w ago

Microfluidic Devices for Imaging and Biochemistry Analysis of Microbes Under Mechanical Pressure https://www.biorxiv.org/content/10.64898/2026.09.06.749717v1

Our collaborative paper, with Daria Bonazzi and @dumenillab.bsky.social is finally out in Nat Comms! Using microfluidic confiners, amazing Laure Leblanc found that confined growth of E. coli uncouples growth and division, as well as pressure and biomass production. tinyurl.com/4zdwrp39

Bacterial growth under confinement requires transcriptional adaptation to resist turgor pressure build-up doi.org/10.1038/s414...

🔬🧪🦠 An exciting opportunity to work at the interface of Fungal Cell Biology & Biophysics in Nice, FR in a collaborative project on roles of cytoplasmic crowding in fungal pathogen morphogenesis, antifungal responses and host interaction. ibv.unice.fr/news/postdoc... Please share/retweet

Please save the date: The Microphysio Conference is back and will be held in Cargèse from April 25th to April 30th! With a great lineup of speakers, it’s an excellent opportunity to exchange ideas in fields related to organ-on-chip, organoids, bioprinting, mechanobiology, and much more! Stay tuned.

Now published in Micro-Nano-Engineering! www.sciencedirect.com/science/arti...

Delarue Research@delarueresearch.bsky.social · 9mo ago

Happy New Year! And happy to share our latest instrumentation work, led by fantastic Ines Muguet. Ines showed that sliding elements, developped by Ben Meriem et al, can be functionnalized to have electrodes, thus allowing reconfigurable electrochemistry-on-chip! Stay tuned, more preprints to come.

Un pétition du collège des sociétés savantes pour mettre en avant le rôle de la recherche dans la campagne politique à venir et rappeler le sous investissement chronique en France depuis 20 ans. N'hésitez pas à faire ciculer recherche-publique-2027.fr

#ResultatScientifique🔎| Quand Candida albicans réduit ses ribosomes, ses cellules deviennent plus fluides, ce qui l’aide à changer de forme et à mieux infecter l’organisme 🍄 ✍️ Robert Arkowitz 📕 @natmicrobiol.nature.com | buff.ly/zPSLael

Fluidité intracellulaire et pouvoir infectieux du champignon Candida albicans

Dans un article publié dans la revue Nature Microbiology, des scientifiques mettent en évidence un mécanisme jusque-là inconnu chez Candida albic

insb.cnrs.fr

Happy New Year! And happy to share our latest instrumentation work, led by fantastic Ines Muguet. Ines showed that sliding elements, developped by Ben Meriem et al, can be functionnalized to have electrodes, thus allowing reconfigurable electrochemistry-on-chip! Stay tuned, more preprints to come.

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 9mo ago

Selective Laser Etching technology for reconfigurable microfluidic and electrochemistry-on-chip https://www.biorxiv.org/content/10.64898/2026.01.08.698316v1

📢 New extended abstract submission deadline: 6 January 2026! Outstanding speaker list, plus many slots for short talks by students, postdocs, and junior PIs. Join us in March in Barcelona! events.ibecbarcelona.eu/embl-ibec-co...

Wonderful collaboration with @robertarkowitz.bsky.social et al! Fascinating result that inhibiting ribosome biogenesis triggers filamentation of C. albicans!

Nature Microbiology@natmicrobiol.nature.com · 10mo ago

#NewResearch During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen. #MicroSky 🦠 www.nature.com/articles/s41...

New preprint from the lab, an old work from Z. Ben Meriem! We compress cells in 2D and show that proliferation and motility decrease. Crowding increases under pressure, which may explain this result. Interestingly, more mesenchymal cells seem to be more sensitive to pressure! tinyurl.com/ybfu62yf

I want to share three reviews on crowding and spatial confinement, active areas of research on our end: - on the dynamic structure of the cytoplasm: tinyurl.com/4d6drhnv - on the sensing of and response to crowding: tinyurl.com/959ht4fw - on the effect of spatial confinement: tinyurl.com/nhh7sk9w

Happy to bring this to light! The result of quite a few years and fabulous collaborations with wonderful colleagues! Thread from Antonio Serrano (@antonioserrano) coming soon!

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 2y ago

Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen https://www.biorxiv.org/content/10.1101/2024.11.16.623909v1

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...

🚨 Excited to share our new study on the human fungal pathogen Candida albicans! Thread 👇 (1/11) biorxiv.org/content/10.1... #Science #Microbiology #CellBiology

This work wouldn’t be possible without the incredible collaboration of wonderful colleagues.Thanks to Charles Puerner, Emily Plumb, Louis Chevalier, Johannes Elferich, Ludwig Sinn, Niko Grigorieff, Markus Ralser, @delarueresearch.bsky.social, Martine Bassilana and @robertarkowitz.bsky.social (9/11)