Some good news—official data released today shows US solar generation continues to grow rapidly and is on track to set new record highs. In March, solar output was up 35% compared to the same time last year!

Akiko Iwasaki and Harlan Krumholz call for Long COVID and chronic disease research funding in the WSJ: “Advancing this research is one of the most effective ways to improve the lives of the tens of millions of Americans with chronic diseases.” www.wsj.com/opinion/how-...

Opinion | How to Lead a Chronic Disease Revolution

Washington has an opportunity to help tens of millions.

wsj.com

This is full of really useful information about #LongCOVID. Congrats, @patientled.bsky.social ! rehabcovidnetwork.med.utoronto.ca/news/patient...

Just sent off bloods for another LC diagnostic study - if you're in Melbourne, Perth or Brissie and haven't participated yet please sign up! They do home visits for housebound folks

In Italy, muscle biopsies from 8 COVID-19 survivors revealed a distinct myopathy marked by damaged blood vessel linings, not seen in steroid-related muscle disease, suggesting long COVID muscle weakness stems from vascular injury, not direct viral attack. www.tandfonline.com/doi/full/10....

Muscle disease in severe COVID-19 patients: a microangiopathic myopathy

Patients surviving coronavirus disease of 2019 (COVID-19) often complain of skeletal muscle weakness that may be very limiting and long-lasting. There are almost no studies on the skeletal muscle o...

tandfonline.com

In the next year or so, I'm hoping that we'll have the results for - Nanoneedle validation study - Several pilot / case studies for mAbs in Long Covid - Early signals from one or more of the JAK-STAT trials (Abrocitinib, Upadacitinib)

Chan Soon-Shiong Foundation will expand PolyBio’s long COVID research with new funding. Support targets SARS-CoV-2 persistence in tissue and its potential role in cancer development. Thank you, @DrPatSoonShiong polybio.org/chan-soon-sh...

Chan Soon-Shiong Family Foundation donation expands PolyBio Long COVID program - PolyBio Research Foundation

Funds will support exploration of SARS-CoV-2’s potential to drive cancer, as well as continued work delineating persistence of the virus in...

polybio.org

goddd the number of things that turn out to be caused (at least partly) by infectious, vaccinatable diseases. apparently some dementia is actually "long chickenpox"? www.theguardian.com/society/2025...

Study finds strongest evidence yet that shingles vaccine helps cut dementia risk

Older adults in Wales who had the jab were 20% less likely to be diagnosed with dementia that those not vaccinated

theguardian.com

But I've been following politics and organizing long enough to know that the Left has a real tendency toward "thing 1 didn't work, everything sucks and is worthless" and all I can tell you is that the Right does not believe that and their success is largely due to their absolute asshole persistence.

Dr. Soon-Shiong: “…is this what I call long COVID, virus persisting?..the group at UCSF has now definitively proven…does that COVID virus suppress the natural killer cell?…it becomes what-you-call-energic? That's now been published. The natural killer cell has gone to sleep."

h/t to Greg Morrow for this-- They cured symptomatic rabies in mice. RABIES. www.embopress.org/doi/full/10....

mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism | EMBO Molecular Medicine

image image Rabies is a fatal viral disease of humans, with uniform mortality once central nervous system (CNS) invasion occurs and symptoms appear. This study demonstrates that a single‐dose monoclon...

embopress.org

🚨THANK YOU #LONGCOVID PATIENT COMMUNITY 🚨 Because of you, NIH RECOVER grant terminations being reversed & restored! This win was only possible due to YOUR advocacy & support from our Hill bipartisan champions! THANK YOU to every person who called, emailed & took action! #NoLongCOVIDCuts

NIH, which began this week terminating projects studying long COVID, has reinstated the grants, after pressure from Sen. Todd Young's (R-IN) office, an HHS source tells me. Young had secured a commitment from RFK Jr that he'd continue funding long COVID research. Story by @thesicktimes.bsky.social

UPDATE: RECOVER Long COVID pathobiology grants restored - The Sick Times

Long COVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, accord...

thesicktimes.org

NEW: The NIH appears to be reversing course on its decision to abruptly cancel a spate of grants for #longCOVID research earlier this week. @cenmag.bsky.social #chemsky #biosky cen.acs.org/policy/resea...

NIH restores some long COVID grants

Researchers still nervous about funding status

cen.acs.org

🚨 BREAKING: Long COVID research grants rescinded earlier this week have been restored, according to researchers & patient reps. Advocates organized quickly yesterday in response to the news, helping reverse the decision. Exclusive in @thesicktimes.bsky.social thesicktimes.org/2025/03/28/u...

UPDATE: RECOVER Long COVID pathobiology grants restored - The Sick Times

Long COVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, accord...

thesicktimes.org

Thank you Senator Todd Young (R-IN), Senator Bill Cassidy (R-LA), @kaine.senate.gov @sanders.senate.gov for your help here! Bipartisan coordinated efforts like this are crucial to support constituents and the world community👏👏👏 Appreciate your leadership!!! #LongCovid #NoLongCOVIDCuts

The Sick Times@thesicktimes.org · 2y ago

🚨 BREAKING: #LongCOVID research grants from the National Institutes of Health’s RECOVER program will be restored following news stories about their abrupt cancellations and advocacy to restore the funding, according to patient representatives in the initiative. bit.ly/3FO8LuQ

Fight back against all their nonsense. Sometimes it works.

Kyle Cheney@kyledcheney.bsky.social · 2y ago

JUST IN: Kari Lake has withdrawn the cancelation of Radio Free Europe’s grant, seeking to end a legal standoff.

The elimination of: grants to study #LongCovid, the Office of LC, & Advisory Committee on LC — have sent a chilling signal. We encourage folks to take the following action led by our partners: 1. Call your reps: win.newmode.net/longcovidcam... 2. Email your reps: actionnetwork.org/letters/long...

DOGE cuts can and do get reversed but ONLY if there is LOUD and IMMEDIATE pushback E.g. FDA medical devices reviewers reinstated a week after being let go - it's possible and it needs to happen for LC Call your reps make sure they hear from us!!

THIS IS HUGE! Researchers at Scripps Research Institute have developed a groundbreaking UNIVERSAL coronavirus vaccine that triggers STONG immune responses AND shows promise in neutralizing MULTIPLE coronaviruses, including those responsible for causing COVID-19, MERS, AND even the “common cold.” 🧪🧵⬇️

The administration has canceled 45 RECOVER #LongCOVID grants. These grants examined pathology, & were vital to understanding infection-associated chronic illness as a whole. Half of those with #LongCOVID at 6 mo. meet criteria for #MECFS. 🧪 cen.acs.org/policy/resea...

NIH cancels grants through flagship long COVID initiative

Termination ‘a waste of the money we’ve spent already’

cen.acs.org

US friends please call your reps 😭🙏 the only hope for saving these grants 🕯 bsky.app/profile/lcca...

Long COVID Campaign | www.longcovidcampaign.org@lccampaign.bsky.social · 2y ago

🚨BREAKING: NIH RECOVER #LongCOVID GRANT CUTS HAVE STARTED🚨 The next 2⃣ DAYS critical to tell Congress #NoLongCOVIDCuts to clinical trials & clinic funding. Can you make just 3⃣ calls & send 3⃣emails today? ☎️Call Congress Tool bit.ly/NoLongCOVIDC... 📨Email Congress Tool bit.ly/NoLongCOVIDC...

#pwLC #pwME #NEISVoid please share with family and friends too! 👇

Long COVID Campaign | www.longcovidcampaign.org@lccampaign.bsky.social · 2y ago

🚨BREAKING: NIH RECOVER #LongCOVID GRANT CUTS HAVE STARTED🚨 The next 2⃣ DAYS critical to tell Congress #NoLongCOVIDCuts to clinical trials & clinic funding. Can you make just 3⃣ calls & send 3⃣emails today? ☎️Call Congress Tool bit.ly/NoLongCOVIDC... 📨Email Congress Tool bit.ly/NoLongCOVIDC...

#MEAction plans to announce our #MillionsMissing campaign next week in which we will rally our community to fight back against these research cuts. TAKE ACTION now by calling your Congressional reps to tell them to STOP the CUTS! See the Long COVID Campaigns toolkit: bit.ly/427IHlE

🚨BREAKING: NIH RECOVER #LongCOVID GRANT CUTS HAVE STARTED🚨 The next 2⃣ DAYS critical to tell Congress #NoLongCOVIDCuts to clinical trials & clinic funding. Can you make just 3⃣ calls & send 3⃣emails today? ☎️Call Congress Tool bit.ly/NoLongCOVIDC... 📨Email Congress Tool bit.ly/NoLongCOVIDC...

Update on Long COVID research funding: Per researcher and advocate @themegascope.bsky.social, funding for at least 45 different RECOVER studies have been terminated. RECOVER is a $1.7 billion program that serves as the single largest federal funding mechanism for long COVID research.

Please make calls to save Long Covid funding! As @ezra.zone has pointed out, it’s not just a few years of research being lost, it’s a generation of researchers who will move on to other issues that have funding… ie less hope this gets solved in our lifetimes 💔 win.newmode.net/longcovidcam...

Beerse, Belgium. In cell and hamster models, researchers found that JNJ-9676, a small molecule targeting the SARS-CoV-2 membrane protein, blocks virus assembly and sharply reduces viral load, offering a new antiviral strategy. www.nature.com/articles/s41...

A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein - Nature

JNJ-9676—a small-molecule inhibitor targeting coronavirus M protein that shows excellent efficacy in Syrian golden hamster models—binds to and stabilizes the M protein dimer in an altered conformation...

nature.com

Leuven researchers screened 350,000 compounds and found CIM-834, a small molecule that blocks coronavirus assembly by locking the M protein in its inactive form. In mice and hamsters, it stopped SARS-CoV-2 replication and even prevented transmission. www.nature.com/articles/s41...

A coronavirus assembly inhibitor that targets the viral membrane protein - Nature

High-throughput screening and hit optimization have led to the development of a small molecule, CIM-834, that targets the SARS-CoV-2 membrane protein and blocks assembly of the virus.

nature.com

A paper in Nature Communications reports PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a radiolabeled human antibody revealing persistent detection in the lung and brain three months after infection. #medsky 🧪

Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates - Nature Communications

There are limited approaches to monitor virus spread in vivo. Here, the authors report PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a radiolabeled human antibody revealing persistent detection in the lung and brain 3 months after infection.

go.nature.com