Harrison Stratton

@hstratton.bsky.social

Neuroscientist | First Gen | Tech enthusiast. Postdoc at University of Pittsburgh studying mechanisms underlying chronic pain in the periphery and spinal cord.

Thank you @usasp.bsky.social and #NAPainSchool! I am truly grateful for this opportunity and chance to learn from the best this summer! 😎🙌

North American Pain School@napainschool.bsky.social · 3mo ago

A big thank you to our incredible partner, @usasp.bsky.social for sponsoring the participation of a trainee at #NAPainSchool! We’re proud to work together in empowering future #pain researchers. 💫 👏 Welcome @hstratton.bsky.social @upittpress.bsky.social

So excited to share our preprint uncovering FGFR3 autoantibodies as pathogenic drivers of pain sensitization. Using patient serum, human DRG and rat models, we found that autoantibodies can find FGFR3 on sensory neurons to induce hyperexcitability and hypersensitivity. #PainResearch #Autoimmunity

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Sensory neuronopathies (SNN) and small fiber neuropathies (SFN) are debilitating disorders associated with neuropathic pain, yet their underlying mechanisms remain poorly understood. Autoantibodies ag...

biorxiv.org

Really enjoyed going to see the Steeler's preseason game yesterday! The Steeler's played well but in the end lost to Tampa Bay. It was my first time to a Steeler's game and I have to say I enjoyed it. Although it was very hot!

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Hats off to lead author Tony Lim who drove this project from writing the fellowship application, to establishing new techniques in the lab. We developed a reversible self-amplifying RNA (saRNA) system that encodes innate immune suppression directly within saRNA. Next step, in vivo!

eLife@elife.bsky.social · 12mo ago

A promising new approach for self-amplifying RNA that avoids triggering strong inflammatory responses in cells, paving the way for safer, longer-lasting gene therapies without immune suppression. buff.ly/xQWCPhJ

graphical abstract