Soham Mukhopadhyay

@sohambio.bsky.social

Plant Pathogen Interaction | Plant Galls | Postdoctoral Fellow & Adjunct Faculty @unm.edu | Associate Editor @MPMI | 🌐 soham.science | Try http://biosearch.chat

As genomes become easy, there is a definite need to really teach species and gene phylogenetic analysis to all molecular biologists and biochemists. If a paper/manuscript shows 1:1 orthologues between monocots and dicots for genes unique to the Brassicaceae, I think that is a major red flag.

Plants use the hormone salicylic acid (SA) to fight infection, but how it activates gene expression remained unclear. Two studies @nature show that the mechanism involves interaction between SA receptor NPR1 and a component of the transcriptional machinery. shorturl.at/7PymL & shorturl.at/Iy4oY

Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors - Nature

Nature - Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors

shorturl.at

Plants can synthesize mimics of the insect molting hormone 20-hydroxyecdysone (20E) to defend against pests. In this preprint, we discover that two plant families independently evolved biosynthetic gene clusters to make 20E. Amazing team effort by my lab! www.biorxiv.org/content/10.6...

Convergent biosynthesis of insect molting hormones in plants

Insect herbivores have driven plants to evolve complex chemical defenses, including mimics of the arthropod molting hormone 20-hydroxyecdysone (20E). Many distantly related plants produce 20E, suggest...

biorxiv.org

Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. https://scim.ag/4nTQ3nq

How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux

Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇

bioRxiv Plant Bio@biorxiv-plants.bsky.social · 5mo ago

A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1

We are excited to release the BAT!🦇🚨 We've used this phylogenetic analysis pipeline in our lab for years, and grad Ben Sheppard now presents a Github release and preprint. I run BAT analyses almost daily. It makes exploring gene families routine, customizable, and fun🧵

pipeline logo

What we more recently learnt about Tiberius: the models trained on softmasked genomes are very sensitive to how the genome was masked for inference. It seems safer to use models trained on unmasked genomes. #genomeannotation #geneprediction github.com/Gaius-August...

GitHub - Gaius-Augustus/Tiberius: Tiberius is a deep learning gene finder.

Tiberius is a deep learning gene finder. Contribute to Gaius-Augustus/Tiberius development by creating an account on GitHub.

github.com

the estimated 1 billion biochemical reactions that occur every second in every cell of our bodies 🤯

Simone Reber@simonereber.bsky.social · 8mo ago

Density. Crowding. Tomato. Tomato 🍅 @gabepopkin.bsky.social kin.bsky.social @quantamagazine.bsky.social Thx for covering the debate! We promise we're all friends 🥰 @liamholt.bsky.social & @gwgl.bsky.social Nothing would have been possible without @gucklab.bsky.social @vasilyzaburdaev.bsky.social