So excited to see this fun collaboration with Andrew Chisholm out in the world. So much to do with this aECM toolkit for matrix biology, aging, stress, pathogenesis research! Found a striking diversity of localization patterns for different components.

PLOS Biology@plosbiology.org · 3d ago

Barrier #epithelia are protected by apical extracellular matrices (aECMs). This Resource by @gotworms.bsky.social @ucscscience.bsky.social &co generates a toolkit of 105 fluorescently tagged aECM components and defines reference markers for key substructures. 🧪 #AcademicSky #Celegans plos.io/4sggBS0

Interested in nuclear mechanobiology and want to know what some of the big open questions are in the field? Read our recent editorial with input from >15 leading experts in the field, along with a list of review articles on nuclear mechanobiology: www.tandfonline.com/doi/full/10....

Nuclear mechanobiology: a brief history and five unresolved questions

Published in Nucleus (Vol. 17, No. 1, 2026)

tandfonline.com

You're probably already doing science advocacy — you just might not call it that. Our new commentary (www.nature.com/articles/s41...) makes the case that every scientist has a role, and that advocacy takes many forms. Find and embrace yours! @natcellbio.nature.com @vfarm15.bsky.social

Every scientist has a role in advocacy - Nature Cell Biology

In this Comment, we call on scientists to share their stories. Through casual conversation or prepared presentations, with images or essays, scientists can advocate for their research and reach taxpay...

nature.com

We have a new paper out today from superstar Nora Herzog! A virus that fluidizes the nucleus to enable replication! Check it out here: lnkd.in/e-xV8acK This was an amazing collaboration with Ian Mohr and Angus Wilson

Nuclear size and physical properties of the nucleoplasm are determined by colloid osmotic pressure at the nuclear envelope https://www.biorxiv.org/content/10.64898/2026.07.21.739918v1

The nucleolus is the largest condensate in the nucleus and the site where ribosomes are built. It has no membrane. It assembles by phase separation, components demixing from the nucleoplasm into a droplet. So what decides when it forms? 🧵🪱💧 www.biorxiv.org/content/10.6...

Check out our new paper! iCLAP: an innovative method for integrable codetection of low-abundance antigens with highplex immunostaining Read more about iCLAP here: www.nature.com/articles/s41...

Don’t forget to register for the C. elegans topic meeting June 10-14 in Madison, WI. Early bird registration deadline this Friday 2/27! uwmadison.eventsair.com/mapsdev26/

New in @quantamagazine.bsky.social: the science of cytoplasmic crowding. From Liam Holt & Simone Reber's work to our discovery that in vivo cytoplasm is 50x more crowded than cultured cells. Thanks @danstarrucdavis.bsky.social & @gabepopkin.bsky.social! www.quantamagazine.org/the-biophysi...

The Biophysical World Inside a Jam-Packed Cell | Quanta Magazine

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

quantamagazine.org

Forget the calm, spacious cells from your biology textbook. Inside a living cell, it’s less “tidy factory” and more “midnight nightclub and the cytoplasm of worm cells is thick as strawberry jam. Congrats, @gwgl.bsky.social! www.quantamagazine.org/the-biophysi...

The Biophysical World Inside a Jam-Packed Cell | Quanta Magazine

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

quantamagazine.org

The call for session proposals for Cell Bio 2026 is open. ASCB gives priority to organizers who haven't run a session in the last two years, and they encourage trainees to submit with an experienced co-chair. Deadline: Feb 22. @ascbiology.bsky.social www.ascb.org/cellbio2026/...

Cell Bio 2023-An ASCB|EMBO Meeting

Network, learn, and collaborate with top cell biologists from around the globe.

ascb.org

TaoChongBao: A Large-Scale Caenorhabditis elegans Mutagenesis and Missense Variant Database Bridging Worm and Human Genomes https://www.biorxiv.org/content/10.64898/2025.12.03.692224v1

www.nature.com/articles/s41...

Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction - Nature Cell Biology

Shen, Gelashvili and Niethammer developed an inner nuclear membrane tension sensor and demonstrated that ER–nuclear membrane contiguity acts as a mechanical buffer.

nature.com

So excited to post my first official #zebrafish paper in my new gig at UC Berkeley with my amazing co-authors @swinburnelab.bsky.social @alinetschanz.bsky.social The TL;DR is that monomeric StayGolds are game changers for in vivo imaging in zebrafish 1/7 micropublication.org/journals/bio...

WormTagDB: A Systematic Survey of Endogenously Tagged Proteins in C. elegans and Roadmap Towards the Tagged Proteome https://www.biorxiv.org/content/10.64898/2025.12.02.691955v1

Grateful to be featured in Nature Methods discussing how @danstarrucdavis.bsky.social and I run the joint Starr-Luxton Lab @ucdavis.bsky.social together. Thanks to Vivien Marx for the thoughtful interview - she really captured what makes this model work. www.nature.com/articles/s41...

This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi

Medicine Nobel goes to three researchers who identified immune system’s security guards

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

scim.ag

This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues go.nature.com/48QDdAJ

Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

go.nature.com

Write your program officer and grants management official TODAY and thank them! It takes 30 seconds and its really appreciated. The only reason they're remotely this close is because those folks are working 60 hour weeks under immense pressure

Jeremy Berg@jeremymberg.bsky.social · last yr.

Here are data on the percentage of FY2024 appropriation committed to date in FY2025. Most ICs are well on track, but four ICs (NIMHD, NINR, NHLBI, NHGRI) still appear to be under 80%. Note that values >100% reflect either a higher appropriation for FY25 or an increased % devoted to grants.

🎉Check out our new preprint!! 🧬We found that lamin mutations in muscular dystrophy don’t just affect the nucleus — they disrupt a nucleolar–ribosomal axis that reorganizes the entire cytoplasm. Very grateful to @danstarrucdavis.bsky.social, @gwgl.bsky.social and our lab for collaboration & support!

GW Gant Luxton@gwgl.bsky.social · last yr.

🧬 NEW Starr-Luxton Lab PREPRINT: Our 🌠grad student @XiangyiDing figured out why muscular dystrophy mutations cause such widespread cellular chaos. The answer wasn't what we expected - and it changes how we think about the disease. Thread🧵 (1/6). www.biorxiv.org/content/10.1...

🧬 NEW Starr-Luxton Lab PREPRINT: Our 🌠grad student @XiangyiDing figured out why muscular dystrophy mutations cause such widespread cellular chaos. The answer wasn't what we expected - and it changes how we think about the disease. Thread🧵 (1/6). www.biorxiv.org/content/10.1...

Centrosomes might look tough, but they are actually big softies - see the latest work from the Dammermann lab now on BioRxiv:

Júlia Garcia-Baucells@jugarbau.bsky.social · last yr.


1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.

Congrats to @xiangyiding.bsky.social et al. on their new study on the intense cellular dance happening in worm cells! 🕺 Dive into the #FrontierScience of organelle crowd control. 👇

GW Gant Luxton@gwgl.bsky.social · last yr.

🧬BREAKING!🪱Plot twist: Cells aren't meditation pools, they're overcrowded concerts with VIP ropes everywhere! Our study reveals worm cells are insanely crowded AND compartmentalized. Ribosomes = packing peanuts, ANC-1 = the bouncer! www.science.org/doi/10.1126/...

🧬Want the full story of our paper without the science jargon? Our @ucdavis.bsky.social department broke down our "cells are crowded AND constrained" findings in plain English! Perfect explanation of why worm cells are nothing like cultured cells 🪱🌠

🧬BREAKING!🪱Plot twist: Cells aren't meditation pools, they're overcrowded concerts with VIP ropes everywhere! Our study reveals worm cells are insanely crowded AND compartmentalized. Ribosomes = packing peanuts, ANC-1 = the bouncer! www.science.org/doi/10.1126/...

Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo

Living tissues maintain unique intracellular biophysical properties under the control of cytoplasmic constraints and crowding.

science.org

🚨Our fabulous graduate student Selin's paper on how the KASH protein UNC-83 regulates the activity of kinesin-1 to control developmental stage-specific nuclear migration is out! Another great collaboration between the Starr-Luxton and MOM labs. www.sciencedirect.com/science/arti...

The KASH protein UNC-83 differentially regulates kinesin-1 activity to control developmental stage-specific nuclear migration

Nuclear migration plays a fundamental role in development, requiring precise spatiotemporal control of bidirectional movement through dynein and kines…

sciencedirect.com

2025 Worm Show youtu.be/HXgUZzLJ-b0?...

Worm Show 2025

YouTube video by Morris Maduro

youtu.be

Our review is out! Such an honor to publish with Ryoko and Michael-early midbody leaders! The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential www.molbiolcell.org/doi/full/10....

The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential | Molecular Biology of the Cell

The midbody (MB), a transient structure formed during cytokinesis, has evolved from a mere structural component to a complex signaling organelle with diverse functions beyond cell division. Recent stu...

molbiolcell.org

Congratulations to Dr. Gümüşderelioğlum from the Starr-Luxton Lab @ucdavis.bsky.social! 🎓 Fresh off her recent PhD defense, she gave an excellent talk this morning at the Cell Biology session of #Worm2025 on UNC-83 molecular switches in nuclear migration. So proud! 👏 #NewPhD #CellBiology

Incredible plenary presentation by Starr-Luxton Lab student @xiangyiding.bsky.social at the International Worm Meeting! Who knew C. elegans cytoplasm has the viscosity of strawberry jam? 🍓 So proud! #Worm2025 #frontierscience @danstarrucdavis.bsky.social