David Oriola
@davidoriola.bsky.social
Interested in the physics of very small living things. Assistant Professor in UPC-Barcelona Tech. Full time dad. Occasional guitar player and dachshund lover. https://davidoriola.mystrikingly.com/
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
Check out our new short review "Cell sorting models in tissue development". This is our contribution to a Special Issue on Modelling and Dynamics in Current Opinion in Systems Biology. @barcelonacollaboratorium.com @biocomsc-upc.bsky.social @upc.edu www.sciencedirect.com/science/arti...
Cell sorting models in tissue development
In animal embryos, cell fate specification coordinates with the spatial organisation of cells into distinct domains, leading to the establishment of e…
sciencedirect.com
After a year of posting the pre-print, we now updated the manuscript in bioRxiv with beautiful agent-based simulations from Sotiris Samatas (EMBL) recapitulating symmetry breaking in gastruloids. @barcelonacollaboratorium.com @embl.org
David Oriola@davidoriola.bsky.social · 2y agoReally happy to share with you my last work from my time in @embl.org with the @viktri08.bsky.social group. We studied the dynamics of cell fate transition in gastruloids and found that cells communicate with each other to control the timing of symmetry breaking. www.biorxiv.org/content/10.1...
New preprint! We show how mesoscopic nonequilibrium fluctuations in active gels emerge from the breaking of detailed balance at the molecular scale. Warning: Long technical paper ahead! Enjoy! @mpipks.bsky.social @ub.edu @ubics.bsky.social @icreacommunity.bsky.social arxiv.org/abs/2601.20483
In previous work with @davidoriola.bsky.social and Jaume Casademunt, we proposed this model and coarse-grained it to show that it gives rise to the constitutive equations of a viscoelastic active gel. link.aps.org/doi/10.1103/...
Fluidization and Active Thinning by Molecular Kinetics in Active Gels
We derive the constitutive equations of an active polar gel from a model for the dynamics of elastic molecules that link polar elements. Molecular binding kinetics induces the fluidization of the mate...
link.aps.org
Ja tens disponible la sobretaula amb el professor i biofísic @davidoriola.bsky.social #LSDLF 🔴YouTube: buff.ly/k10Jddt 🟢Spotify: buff.ly/ZLpeVK3 🟠iVoox: buff.ly/vhI2R8G
We offer a 1-year postdoc on modelling multicellular systems in my group at @biocomsc-upc.bsky.social and @barcelonacollaboratorium.com in sunny Barcelona. We encourage applicants to also apply for a Juan de la Cierva Fellowship for a 2-year extension. Feel free to contact me!
🚨JOB ALERT Dr. Buceta at @i2sysbio.es welcome applications for 36-month postdocs on: 👉 Mechanical markers of tissue dysfunction due to ageing – digital twins & machine learning Details here: fgcsic.es/convocatoria... 📩 Contact javier.buceta@csic.es to shape your proposal! @epimechfc.bsky.social
ComFuturo Fourth Edition: ComFuturo iAGE Call - FGCSIC
The Fundación General CSIC (FGCSIC) launches the fourth edition of its ComFuturo programme: ComFuturo iAGE, a postdoctoral initiative co-financed by the Marie Skłodowska-Curie Actions COFUND scheme of...
fgcsic.es
Emergence and Self-organisation across biological scales! I hope you are ready for next year conference! It will be an incredible event April 20-22 2026. The first of many #LakeConference organised by @ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org
allen institute@alleninstitute.org · 9mo ago#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel! 📆 April 20-22, 2026 📍 Seattle, USA 🔬 All career stages welcomed. Apply to attend by 12/12: alleninstitute.org/events/aics-...
We offer a 1-year postdoc on modelling multicellular systems in my group at @biocomsc-upc.bsky.social and @barcelonacollaboratorium.com in sunny Barcelona. We encourage applicants to also apply for a Juan de la Cierva Fellowship for a 2-year extension. Feel free to contact me!
We’ve officially launched the MetaboDev lab at IMBA 🚀! I’m extremely grateful for all the support from the @imbavienna.bsky.social & @viennabiocenter.bsky.social community. Special thanks to @eunicechan.bsky.social, the most amazing first lab member I could have hoped for. On to the science!🔬🧬#NewPI
Institute of Molecular Biotechnology@imbavienna.bsky.social · 10mo agoIn our latest interview, Kristina Stapornwongkul, the newest group leader at IMBA, shares her journey to joining the institute, why she chose IMBA as the next step in her career, and her vision for her lab exploring how metabolism shapes embryonic development: https://imba.science/49fCrxl
Join us next week for another exciting VGZT session! 🗓️ Thursday, November 6th ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET Our speakers are 👉 David Oriola (@davidoriola.bsky.social) 👉 Nicole Edwards (@nicoleedwds.bsky.social) See you then! 👋
With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend. mpl.mpg.de/news/article... @fau.de 📸 Stephan Spangenberg
Amazing!!! 🧪 The 2025 Ig Nobel prize goes to scientists from the @mpipks.bsky.social for discovering a bullet proof version to make the classic pasta alla cacio e pepe! Including a deep understanding of the pasta sauce in terms of phase separation physics 😃 Congrats @gbart.bsky.social et al! Links👇
One is the best EMBO/EMBL symposium is coming up and it’s going to be AWESOME. Save the date !
Aileen Berasategui@berasymbionts.bsky.social · 12mo ago🚨 Save the date! Thrilled to be co-organizing the next iteration of the @embl.org Symposium on the Cellular Mechanics of Symbiosis (📅 March 17-20), w/ @floravincent.bsky.social, @hassansalem.bsky.social & Tom Richards. www.embl.org/about/info/c... #EESSymbiosis #Symbiosis #SymbioSky #MicroSky 🦠
Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!
A label-free method for measuring the composition of multicomponent biomolecular condensates - Nature Chemistry
Biomolecular condensates are made of multiple components but current techniques cannot capture their complex composition quantitatively. Now it has been shown that the dense-phase binodal point defini...
nature.com
Physics of Life Dresden@poldresden.bsky.social · 12mo agoNew findings out today in Nature Chemistry from the Brugués @brugueslab.bsky.social at PoL, alongside colleagues at @mpi-cbg.de and the IPF Dresden 🧪 The authors have discovered a new method to identify the molecular makeup of biomolecular condensates Read our press release here: tud.link/ajwtaz
Congratulations, Michael Dorrity and Anna Erzberger! The two EMBL Heidelberg group leaders have received ERC Starting Grants that will enable ambitious projects related to developmental timing and tissue self-organisation, respectively. Learn more: www.embl.org/news/awards-...
🧩 Day 5! Agent-based modeling took center stage today with Alexandria Volkening 🐟🌀 From swarming to zebrafish stripes, participants explored how cells self-organize. ✨ Flash talks & a keynote by Katie Bentley wrapped up the day! #EMBOMulticellModeling
🧠 Day 4 was all about 🧬 noise in biology — from master equations to stochastic simulations, led by Jordi Garcia-Ojalvo! 🔬 Group projects continued, and the day ended with a fascinating keynote by @jamesbriscoe.bsky.social on morphogen mediated tissue patterning! #EMBOMulticellModeling
🧬 Day 3! From spatial models and Turing patterns to the interplay of gradients and self-organisation, today was packed with insights and hands-on work. Participants also began their group projects and wrapped up the day with an inspiring keynote by @bertaverd.bsky.social! #EMBOMulticellModelling 💡🧠
🧪 Day 2 of the EMBO Practical Course at the Collaboratorium! From solving ODEs in Python to applying them to gene regulatory networks and diving into object-oriented programming with VEDO. #EMBOMulticellModelling 💻🧬
🔬 Day 1 of the EMBO Practical Course on Computational Modelling of Multicellular Systems kicks off at the Collaboratorium! Participants were welcomed by @jamesasharpe.bsky.social, setting the stage for a week of exploring how computational tools help us understand tissue and organ dynamics. 💻🧬
Amazing defense by @alisonkickuth.bsky.social! Congratulations on the beautiful thesis!
Alison Kickuth@alisonkickuth.bsky.social · last yr.I successfully defended my PhD thesis this week! Thank you @brugueslab.bsky.social, @poldresden.bsky.social and @mpi-cbg.de for the great time over the last years!
After its renewal last week, our Excellence Cluster Physics of Life will be taking on new challenges! In the upcoming weeks, we will be explaining here our new scientific directions, represented by 7 interwoven Research Avenues🔬👩🔬 Stay tuned! Learn more: tud.link/5f2m72 #biophysics #research #dfg
50+% cut to the US National Science Foundation budget is staggering. These include cuts for research in Chemistry. Physics, Geology, Math, Engineering, Computer Science. Scientific discoveries and training of our next generation of scientists and engineers are halved. How is that helping the US?
Nucleoli as biomolecular bubble tea! Congrats to former Princeton ugrad Holly Cheng (now GS @MIT) ->Holly's senior thesis work, a close collab w Roggeveen Wang & @zs-biophys.bsky.social &Stone. Come for the cool movies & stay for the viscoelasticity! www.pnas.org/doi/10.1073/pnas.2407423122
Flocking and active solid behavior of epithelial cells in our new study in @pnas.org Great work of Y. Shen, J. O'Byrne and @andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez! | PNAS www.pnas.org/doi/10.1073/...
