Bernhard Staresina

@bstaresina.bsky.social

Professor of Cognitive Neuroscience University of Oxford https://www.staresinalab.com/

🌙 Our new preprint is out! We present Nyx, an open-source unsupervised framework for sleep scoring across species, lifespan and modalities. Validated on 19 datasets and 8,000 hours of sleep, from mice to humans, lizards and birds, across development, ageing, health and disease.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last wk.

Nyx: a flexible framework for sleep scoring across species, lifespan and modalities https://www.biorxiv.org/content/10.64898/2026.07.24.740558v1

New preprint! We show low arousal states promote hippocampal ripple genesis in sleep and wake. This bridges rodent work, where ripples predominate during sleep, with human studies reporting ripples during active behavior, identifying low arousal as a common mechanism www.biorxiv.org/content/10.6...

Arousal state modulates human hippocampal ripples

Hippocampal ripples are transient, high-frequency oscillations linked to memory replay and consolidation. Ripples are well-characterized in rodents to occur during periods of behavioral inactivity (i....

biorxiv.org

🔔 Preprint: “Hippocampal ripples evoke a stereotyped cortical response followed by spindle-mediated network synchronization.” Combining iEEG+scalp EEG during sleep, we show that hippocampal ripples leave a decodable cortical fingerprint and are followed by brain-wide spindle synchronization!

doi.org

How are memories consolidated during sleep? Excited to share another preprint: hippocampal SWRs route memory content to the cortex via interregional co-reactivation of concept cells, optimized by slow-oscillation–spindle coupling. With the great @tschreiner.bsky.social @humansingleneuron.bsky.social

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 7mo ago

Sequential coupling of sleep oscillations enables concept-neuron reactivation and supports information flow across the human hippocampal-cortical circuit https://www.biorxiv.org/content/10.64898/2026.01.15.699122v1

🚨Preprint: Semantic Tuning of Single Neurons in the Human Medial Temporal Lobe 1/8: How do human neurons encode meaning? In this work, led by Katharina Karkowski, we recorded hundreds of human MTL neurons to study semantic coding in the human brain: doi.org/10.1101/2025...

Semantic Tuning of Single Neurons in the Human Medial Temporal Lobe

The Medial Temporal Lobe (MTL) is key to human cognition, supporting memory, emotional processing, navigation, and semantic coding. Rare direct human MTL recordings revealed concept cells, which were ...

doi.org

Memory problems will change how you see the world...literally 👀 Across two new papers, we examined the eye movement patterns of younger adults, older adults, individuals with mild cognitive impairment, and amnesic cases. 1/5

Excited to share our new study on how respiration modulates neural dynamics during successful memory retrieval—led by @estebanbt.bsky.social, alongside the exceptional team of @fabian31415.bsky.social, @maritpetzka.bsky.social, @tobiasstaudigl.bsky.social, and @bstaresina.bsky.social. 👇

Esteban@estebanbt.bsky.social · last yr.

Very excited to share the first preprint of my PhD thesis! Together with @tschreiner.bsky.social, we investigated how respiration coordinates signature neural expressions of successful remembering during memory retrieval. 🫁🧠 🧵(1/8)

The Staresina Lab is ready for CNS 2025 in Boston!🇺🇸 If you are around come and check out our work at the following poster sessions: Poster Session C Poster C16: Coupled sleep rhythms in the human hippocampus support memory consolidation - Sha, Manqi