@brittanyabaker.bsky.social

Postdoc at Institut Pasteur, investigating the evolutionary transitions among diverse groups of archaea

I'm reposting this because I want to make a correction. In the thread below I mention using the -mset flag for testing site profile mixture models. But in fact you should use -madd flag. I'm sorry for this mistake.

Andrew Roger@andrewjroger.bsky.social · 5mo ago

So you are using IQ-TREE to estimate a tree for "deep time" phylogenetics using amino acid alignments. There is a lot of confusion about how to test model fit. Here are some suggestions.

1/ Our new paper in Systematic Biology "Modeling Site-and-Branch-Heterogeneity with GFmix" led by @cgpmcc.bsky.social describes improved ways to model compositional heterogeneity across both sites and branches—an important source of error in deep phylogenomics. doi.org/10.1093/sysb...

Modeling Site-and-Branch-Heterogeneity with GFmix

Abstract. Phylogenetic trees are often inferred from protein sequences sampled from diverse taxa across the tree of life. The compositions of these amino a

doi.org

Archaea Power Hour returns next WEDNESDAY, May 20th, at 10AM EST / 4PM CET for the final installment of our spring semester seminar series!! We have two exciting talks planned for you so check your email for the Zoom link (coming soon) or visit our website (link in bio) for more info on how to join.

Bild

🚨 Archaea alert 🚨!! We’re back this Wednesday, April 22nd, at 10 AM EST / 4 PM CET with two exciting research talks! You won’t want to miss this so check your email for the Zoom link or visit the link in our bio for more info on how to join the community 🦠

Bild

We have just published a short note on archaeal phylogeny: complex mixture models support a deep placement of Methanonatronarchaeia within Euryarchaea and indicate that three recently described groups (Halorutilales, Afararchaeaceae, and Ordosarchaeia) are actually the same. shorturl.at/5GMpU

Bild

So you are using IQ-TREE to estimate a tree for "deep time" phylogenetics using amino acid alignments. There is a lot of confusion about how to test model fit. Here are some suggestions.