John De Vos
@jdevos.bsky.social
#StemCells Researcher | Director of the Cell Processing Facility University of Montpellier - CHU of Montpellier | #StemCells #iPScells for #lung #CellTherapy | Stem Genomics co-founder | President of the FSSCR
[Resources] #AlphaFold protein and PPI prediction databases 1️⃣ Predictomes (genome maintenance & H2A/H2b) predictomes.org 2️⃣ Flypredictome www.flyrnai.org/tools/fly_pr... 3️⃣ Human interactome prodata.swmed.edu/humanPPI 4️⃣ BFVD (viral proteins) bfvd.steineggerlab.workers.dev 1/2
🧬 Connecting new ideas in Stem Cell Biology! Join leading scientists from Europe, Canada & the U.S. for the 6th International Conference on developmental, adult and cancer Stem Cells. 📍 Lyon, France 📅 October 1–2, 2026 By Aurastem buff.ly/NRKL0Pg #StemCells, #Development and #Cancer
@biorxivpreprint.bsky.social A Cytokine Receptor Signaling Atlas Reveals How STAT Mosaics Fine-Tune T Cell Function www.biorxiv.org/content/10.6... @stanforduniversity.bsky.social
🔥📣[COMMUNIQUE] de l'ancien Président de la Conférence des Présidents d'Universités @jlsalzmann.bsky.social, lui-même Professeur de médecine sur les 850 études de l'IHU suspectées illégales. Sans précédent sans l'Histoire mondiale. Il n'a pas de mots assez durs. Et la justice ne fait... rien. RT SVP🔽
His words came true. Democracy can hardly be expected to flourish in societies where political and economic power is being progressively concentrated and centralized. But the progress of technology has led and is still leading to just such a concentration and centralization of power. Aldous Huxley
Anti-CD19 #CARTCells can persist up to 10 years after infusion in patients with lymphoid malignancies. In one patient CART cells comprised 1.2% of circulating T cells at 9y. Long-term persisting CART cells were predominant double-negative (CD4−CD8−), effector-memory-like phenotype. buff.ly/FBYeuwR
Prenez soin de vos yeux ce soir!
Mark Wallace@wallaceme.bsky.social · 3w agoSomething to ponder this week.
A growing number of private firms are offering researchers artificial-intelligence tools for scrutinizing manuscripts before publication go.nature.com/4wSqQgQ
This AI tool claims to pick the top 1% of preprints. Should researchers trust it?
QED Science says that its metrics reduce bias by assessing papers solely on the basis of their originality and validity.
go.nature.com
Encouraging results for CAR-T in recurrent glioblastoma: intracranial B7-H3 CAR-T (TX103) was well tolerated in a Phase 1 trial (n=15), with no DLTs. Median OS reached 19.1 months, with 66.7% alive at 12 months and one sustained complete response. Phase 2 warranted. #CARTcells buff.ly/1hWb3c9
‘A chilling effect’: China biotech will slow as it nears R&D frontier, Pfizer’s Baum predicts . buff.ly/VydvQje/
Against all odds, with an HHS that has defunded mRNA research programs, the FDA just approved the first mRNA flu vaccine
#SamediCuiCui Poke @khoyoulaa.bsky.social et @transvinylexpress.eurosky.social 🎨 : Rebecca Rebouché - Swan Tree (from her Modern Mythology series)
Thrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote 1/n
Global warming is already harming human health in countless ways. We can now add smoke-related deaths to the growing list. By David Wallace-Wells of the NYT. www.nytimes.com/2026/07/22/o...
Hopstem has received FDA IND clearance and Fast Track designation for its allogeneic #iPSCells-derived forebrain neural progenitors therapy in both hemorrhagic stroke and traumatic brain injury. Hopstem is a Chinese company (Hangzhou) also based in Houston. #StemCell #Stroke
Industry News and Analysis | FirstWord PHARMA
Stay updated with the latest news, insights, and analysis from FirstWord PHARMA. FirstWord PHARMA provides comprehensive coverage of key developments and trends.
firstwordpharma.com
“You will get the country you voted for. That country is one where we will no longer innovate. We will be less secure, less healthy, and less wealthy because some community of people who influence what this country is do not see the value of science” - Neil deGrasse Tyson — It’s already too late.
📣 SAVE THE DATE! The 8th FSSCR Meeting will be held in Paris from Tuesday 11 to Thursday 13 May 2027. As usual, our scientific committee is curating an exceptional lineup of prestigious speakers (to be announced soon) from some of the most renowned research centres. STAY TUNED. #FSSCR #StemCells
@kenaitx.bsky.social has completed enrollment in the Phase 1b/2a REPLACE™ trial of RNDP-001, an off-the-shelf allogeneic dopaminergic neuron replacement therapy derived from #iPSCells. Early efficacy data are now eagerly awaited. #CellTherapy buff.ly/XD3llbo
Kenai Therapeutics Announces Completion of Enrollment in Phase 1b/2a REPLACE™ Trial of RNDP-001 — Kenai Therapeutics
Kenai Therapeutics, a clinical-stage biotechnology company pioneering next generation approaches to cure neurological conditions, today announced the completion of enrollment for the REPLACE™ Phase…
kenaitx.com
Awesome #evolution tool shows when humans separated from other species: 1bn years fungi, 6m years chimpanzees. Source: buff.ly/2l0gV64
Tech companies treating cautionary tales from science fiction as product roadmaps is one of my least favorite things about this timeline.
An AI-generated small-molecule inhibitor treats fibrosis in vivo and in phase I clinical trials go.nature.com/3IvPOuI rdcu.be/d8EOQ
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models - Nature Biotechnology
An AI-generated small-molecule inhibitor treats fibrosis in vivo and in phase I clinical trials.
go.nature.com
In June, genome-editing pioneer Sangamo Therapeutics filed for bankruptcy. A change of era for one of the field's early trailblazers. buff.ly/wgGhrdh
From cloning to gene-editing: the enduring legacy of Dolly the sheep. 30 years after. buff.ly/5REIgRz
From cloning to gene-editing: the enduring legacy of Dolly the sheep
Dolly’s brush with celebrity could hold lessons for current discussions about reproductive technologies.
nature.com
Encouraging early clinical data for #iPSC-derived #CART therapy in autoimmune disease. Off-the-shelf FT819 showed promising activity in systemic sclerosis patients, with no CRS, ICANS or GvHD reported. A potential step toward on-demand CAR-T. #CellTherapy #ISSCR2026
📢 Les inscriptions au Diplôme Universitaire « Thérapies Cellulaire & Génique – Médecine Régénératrice » de la Faculté de Médecine de Montpellier sont ouvertes! 📅 Formation intensive du 9 au 20 novembre 2026 💻 Accessible en présentiel ou en distanciel 😀 Inscriptions : buff.ly/5jebkp6
Cette animation est saisissante. Elle montre, en seulement quelques secondes, l'accélération spectaculaire de la fréquence des vagues de chaleur au cours des 126 dernières années en France. 1/3
The pace of AI progress is exponential. So is its capacity to create value. This argues against an AI bubble.
Dare Obasanjo@carnage4life.bsky.social · 2mo agoThe full SemiAnalysis article is below
Network-driven discovery of repurposable drugs targeting hallmarks of aging @nataging.nature.com @barabasi.bsky.social @northeasternu.bsky.social www.nature.com/articles/s43...
Intravesical mesothelin-based CAR T cells targeting MUC16 effectively control bladder cancer in preclinical models @jem.org @roswellpark.bsky.social @weillcornell.bsky.social rupress.org/jem/article/...
