Claire Foldi
@foldi.bsky.social
Neuroscientist studying the biological mechanisms of eating disorders in Melbourne, Australia. Mother of cats and graduate students. https://www.monash.edu/discovery-institute/foldi-lab
Excited to be presenting our symposium, "From synapse to self: computational, brain imaging and preclinical perspectives on psilocybin’s therapeutic mechanisms", at #NeuroAlliance2026! Featuring: 🧠 Claire Foldi 🧠 @lenaedibrainz.bsky.social 🧠 @adeelrazi.bsky.social 🧠 Nicholas Everett
I am happy to share our latest manuscript, led by newly-minted PhD Justin Wang, identifying a neural population that selectively controls hedonic, but not homeostatic, feeding. www.biorxiv.org/content/10.6...
Ventral pallidal GABAergic neurons control hedonic feeding and obesity
Food intake is governed by two interacting drives. The homeostatic hunger drive regulates food intake to fulfill caloric needs while the hedonic drive promotes intake of palatable foods outside of cal...
biorxiv.org
Thanks Lizzie! Forgot to post 🫠 but this work is extra special… the last project led by @kynaconn.bsky.social before she left the lab to follow her new path. Well done mate, and thanks to all the legends who contributed to this work 🙏🏻
Lizzie Manning@drlizziemanning.bsky.social · 3mo agoExciting new work from @foldi.bsky.social 🍄↔️🧠
1/8 🧵 Breaking: Groundbreaking study drops in Psychedelics! Psilocybin's effects on social behavior & inflammation in female mice modeling anorexia nervosa? TOTALLY context-dependent on metabolism & exercise. Explains why only ~40% respond in human trials. Implications for personalized therapy!
After a busy semester of teaching it is so nice to be at the Biological Psychiatry Australia Conference. First up today is @foldi.bsky.social and team with the development of a 'library of animal models', which sounds like a fantastic resource for researchers studying clinical symptoms/disorders
Hey bsky-ers! New preprint from the lab on #psilocybin & social behaviour in #female mice in contexts relevant to eating disorders (food restriction, exercise & combo of) by PhD student Sheida 💙🦋
bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 10mo agoPsilocybin exerts differential effects on social behaviour and inflammation in mice in contexts of activity-based anorexia (ABA) https://www.biorxiv.org/content/10.1101/2025.10.14.682467v1
Incredibly proud of @kxhuang.bsky.social for persisting with such a challenging dataset from her PhD! We found some intriguing genetic targets in a corticostriatal circuit that may be involved in the development of #anorexia nervosa 🤔 onlinelibrary.wiley.com/doi/10.1002/...
Toward a Genetic Signature of Resistance to Activity‐Based Anorexia in Striatal Projecting Cortical Neurons
Objective Converging evidence from neuroimaging studies and genome-wide association study (GWAS) suggests the involvement of prefrontal cortex (PFC) and striatum dysfunction in the pathophysiology o...
onlinelibrary.wiley.com
A starter pack including all attendees (that I can find for now) Please let me know if I missed anyone! #GRCPsychedelics go.bsky.app/2ExXJcr
Today is the day! I can officially share my promotion to Associate Professor at @monashuniversity.bsky.social 🎉🎉 - Thanks to my lab (past and present), colleagues, letter writers and supporters 😊
Examining the biological causes of eating disorders to inform treatment strategies — a Review by Claire J. Foldi & Kristi R. Griffiths @foldi.bsky.social www.nature.com/articles/s41... #neuroscience #neuroskyence
Examining the biological causes of eating disorders to inform treatment strategies - Nature Reviews Neuroscience
Recent years have seen a growth in our understanding of the biological drivers of eating disorders and their interactions with environmental and psychosocial factors. Foldi and Griffiths consider how ...
nature.com
Writing this was like any other act of love - awkward at the start, frustrating at times, but something to be proud of. Very grateful to Dr Kristi Griffiths for agreeing to take on this challenge with me for @natrevneuro.nature.com www.nature.com/articles/s41...
Examining the biological causes of eating disorders to inform treatment strategies
Nature Reviews Neuroscience - Recent years have seen a growth in our understanding of the biological drivers of eating disorders and their interactions with environmental and psychosocial factors....
nature.com
The 15th Annual BPA Meeting is fast approaching, and we are so pleased to announce this year's excellent symposia line up! Head to our website to confirm your membership for this year + stay tuned for symposium details, general abstract submission & early bird registration🧠 #BPA2025
We created a photometry python package for unbiased standardised post-hoc analysis using bootstrapping confidence intervals No more AUC or time bins analysis! Ever Follow our simple step by step instructions. @foldi.bsky.social @philjrdb.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
For those hurting after DP EOI outcomes today, courtesy of ChatGPT (I prompted with the first line, it will have to go over 2 posts as it's too long): Oh ARC, why won't you fund me? I’ve written papers, set them free, With research deep and insights bright, Yet still, no grant, no guiding light.
Now that she's finally migrated from the Other Place I can officially congratulate @kynaconn.bsky.social on winning a prestigious Early Career Postdoctoral Fellowship from our Faculty @monashuniversity.bsky.social - Well done Kyna!! 🤩
Our paper is out in DPP! This is the SECOND paper from my lab, but the first headed entirely by summer students: College senior Benjamin Babaev and High school senior Saachi Goyal (!!). They also created an easy to use site so anyone can use the machine learning resource for staging estrous cycle
NPP-Digital Psychiatry and Neuroscience (DPN)@dpn-journal.bsky.social · 2y ago🆕 in DPN‼️ @rossenator.bsky.social & co @einsteinmededu.bsky.social developed an object detection machine learning tool to identify cell types of the estrous cycle in mice, providing a fast & reliable method for estrous cycle monitoring in neuroscience studies! www.nature.com/articles/s44...
A perfect score for the R13 proposal for the GRC Psychedelics conference #GRCPsychedelics - what a delight to receive the news before the holidays 💯🎁 The proposal will entirely go towards supporting travel awards and events for trainees. www.grc.org/neurobiology...
“To write well is to think clearly” - which is to say that by delegating more and more of your writing effort to AI, you are inviting the slow erosion of your own ability to think clearly.
We’re launching the Monash Psychedelic Education Program in 2025! Registrations are NOW OPEN for undergraduate and postgraduate education in psychedelic science and therapies! Options for EVERYONE, ANYWHERE. Clinical training coming in 2026! Visit: www.monash.edu/psychedelic-education
All I have seen on here for days is #ACNP2024 posts and the pain of jealousy hurts more than the unquestionable jetlag that would accompany such a trip. How does an extra-US gal like me score an invite for 2025?
The glass paperweight award I have always dreamed of. Couldn’t have done it without my amazing lab - who refuse to join this platform so may not have jobs for long 🩵
Not sure who needs to hear this but the only thing a first draft has to do is exist. Everything else comes later.
A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S...
authors.elsevier.com
My lab has been slow on the 🦋uptake, despite my nagging, but please welcome and follow these two brilliant neuroscience students @kxhuang.bsky.social & @kasparmccoy.bsky.social (hopefully more will follow suit)
If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs
Opposite responses to reward with dopamine (up) and serotonin (down) in nucleus accumbens boost reinforcement learning. Impressive work in Nature: www.nature.com/articles/s41...
Opponent control of reinforcement by striatal dopamine and serotonin - Nature
Nature - Opponent control of reinforcement by striatal dopamine and serotonin
nature.com
If you really want to encounter a lot of views different from your own, go read some books. You don’t need right wing assholes screaming at you on social media for that. This can just be a place where you chill.
