Subhojit Roy MD, PhD
@roylab-ucsd.bsky.social
Science & Music. Sometimes funny. www.roylab.org https://www.youtube.com/@pandemicmelodica
We're now accepting submissions for our next special issue, which will focus on 'Proteostasis' and will be coordinated by two of our Academic Editors, Pedro Carvalho and Tamotsu Yoshimori. Submission deadline: 2 November Find out more: journals.biologists.com/jcs/pages/pr... #proteostasis
This is the future of cognitive surrender.
Ran Blekhman@blekhman.bsky.social · last wk.This is the future of scientific papers. Instead of a PDF, the paper is an AI agent that you can talk to, ask questions, run analyses. No more digging through supplements - just ask the paper directly: "what p-value cutoff was used in Fig 3B? Re-run at 0.01." www.nature.com/articles/s41...
It was so much more interesting to read about Diego Córdoba and Luis Martínez-Zoroa, rather than a stupid machine that spits out numbers. www.quantamagazine.org/ai-has-solve...
AI Has Solved One of Math’s $1 Million Millennium Prize Problems | Quanta Magazine
Mathematicians at OpenAI showed that the Navier-Stokes equations, which describe how fluids flow, can sometimes “blow up.” But the massive result is not without controversy.
quantamagazine.org
Trying to play Finnish Scrabble with English words but I've run into an issue #helsinki @m1singh.bsky.social
Next Monday, we welcome Prof. Subhojit Roy @roylab-ucsd.bsky.social for a Field of View guest seminar on "Neuronal Trafficking in Physiology and Disease" 🗓️ August 31, 11.00-12.00 EEST 📍Auditorium Biologi, BioCity, Turku Host: Guillaume Jacquemet @guijacquemet.bsky.social Feel free to join!
Looking forward to speaking at this synmposium.
BioCity Turku@biocityturku.bsky.social · 2mo ago📣 REGISTER THIS FRIDAY to 35th BioCity Symposium: VISION, EXPANDED bit.ly/4f6kuUR 27-28 August 2026 in BioCity, Turku, Finland Welcome everyone! @utu.fi @turkubioimaging.bsky.social @eurobioimaging.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social
"Wheeling freely in the gaps of human knowledge is this India wicketkeeper batter" www.cricinfo.com/story/sl-vs-...
The trouble with trying to understand Rishabh Pant and cricket's Three Body Problem
He is quite simply the glitch in cricket's increasingly data-driven matrix: a force of chaos that no algorithm, model or physicist can quite explain
cricinfo.com
Didn't realize reason behind the killer bass line in 'I want to Break Free'"
The 70s Guy@stevenw888.bsky.social · last mo.Born 19 Aug 1951, John Deacon, bass player with Queen. He was the last to join the band and also the youngest. Deacon wrote a number of Queen's hit singles, including 'You're My Best Friend', 'I Want to Break Free', & the band's biggest hit in the US, 'Another One Bites the Dust'. #JohnDeacon #Queen
Looking forward to giving a talk next week in Turku, Finland at 35th BioCity Symposium: VISION, EXPANDED (thanks @guijacquemet.bsky.social !): biocityturku.fi/biocity-symp...
BioCity Symposium - BioCityTurku
35th BioCity Symposium: VISION, EXPANDED 27–28 August 2026Mauno Koivisto Centre, BioCity, Turku, Finland Turku is the beating heart of European imaging! The 35th BioCity Symposium “Vision, Expanded” b...
biocityturku.fi
Ok, we know nothing about the brain "More than 80% of eliminated dendritic spines reappeared at their original locations after recovery [from hibernation]": www.science.org/doi/10.1126/...
Artificial hibernation reveals synaptic engram architecture associated with memory retention
Memories leave lasting physical changes at the synaptic level. Although stable, larger spines are thought to support memory, the high turnover of dendritic spines and the drifting of neuronal represen...
science.org
NIH will now attach Gold, Silver or Black stickers to your grant: grants.nih.gov/grants/guide...
NOT-OD-26-088: Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review NOT-OD-26-088. NIH
grants.nih.gov
Walked into lab today and talked about funding crisis, climate collapse and the cosmic meaningless of human existence. Wasn't the best idea.
I've been wondering how to spot good scientists and found the answer in @themarginalian.org.web.brid.gy 's book TRAVERSAL
"You have not become less capable. You have simply become less novel" - The Second Half of life www.linkedin.com/pulse/what-m...
What My Tattoo Artist Taught Me About Work After 50
A seven hour tattoo session became an unexpected lesson about work, identity, and life after 50. Yesterday, I spent the first of three seven hour sessions questioning someone who didn’t need to prove ...
linkedin.com
"Every day, we manage veterans whose conditions are profoundly complex, trauma deep, and suffering [that] can turn dangerous. This is not routine primary care; it is a form of service..." @m1singh.bsky.social 's colleague about what VA doc's life has become: www.annfammed.org/content/24/4...
Maybe I Should Have Taken the Fork
In this reflective essay, a primary care physician describes practicing within the Department of Veterans Affairs during a period of workforce reductions, policy shifts, and changing institutional pri...
annfammed.org
Twenty years ago, Addgene co-founder Melina Fan, PhD, couldn’t get the plasmids she needed for her research, so she helped build a better way to share them. 🧬 On Aug. 1, Melina stepped into a new role as Chief Scientific Advisor. A thank-you and a look at what’s next:
blog.addgene.org
Thank You, Melina: A New Chapter After 20 Years
twp.ai
"The early video store was often a place to talk as well as to shop, and the persona and expertise of retailers and clerks structured the consumer experience of home video as much as the shelves on the wall" I still have my Blockbuster card. thereader.mitpress.mit.edu/the-lost-civ...
The Lost Civic Life of Movie Rental Stores
Decades before recommendation algorithms, video stores served as social hubs where conversation and camaraderie became a form of taste-making.
thereader.mitpress.mit.edu
Key argument why academia is trash...every human "must be a strong business asset" (view shared by the mythical "requiter"):
Every trainee thinks that they can write a paper whenever they want. Some divine intervention will happen as and when necessary, but there is no need to practice anything. Newsflash: You can't just wake up one day and start writing. Just like you can't wake up one day and start playing the cello.
"For anyone with an Internet connection and a little discretionary income, the contemporary moment offers a superabundance of seductive distractions" www.theguardian.com/us-news/ng-i...
Why does everything feel so joyless? Welcome to the age of decadence without pleasure | Michèle Mendelssohn and Charlie Tyson
Decadence in our era comes in technologically mediated forms, emptied of desire and obsessed with self-optimisation
theguardian.com
"Jared Cooney Horvath said Gen Z is less cognitively capable than previous generations, despite its unprecedented access to technology...Gen Z is the first generation in modern history to score lower on standardized tests than the previous one" fortune.com/article/how-...
The U.S. spent $30 billion to ditch textbooks for laptops and tablets: The result is the first generation less cognitively capable than their parents | Fortune
Neuroscientist Jared Cooney Horvath said older generations “screwed up” giving students access to so much technology: “I genuinely hope Gen Z quickly figures that out and gets mad.”
fortune.com
Very excited for our new paper, now out in @cellcellpress.bsky.social! /🧵 The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...
Arc mediates intercellular tau transmission via extracellular vesicles
Tau pathology spreads cell to cell, but the mechanisms of intercellular tau transmission remain unclear. We find that the neuronal gene Arc is critica…
authors.elsevier.com
Interesting to see how few of the "1% papers" say something definitive with a high degree of certainty. Give me something I know is real has become gimme something fuzzy but scintillating that can go in glossy journal. I don't know how to do science anymore.
Richard Sever@richardsever.bsky.social · 3mo ago"the first validated, large-scale framework for judging the quality of life science papers independently of venue, identity, and prestige...Blinded domain-expert professors sided with score three times more often than with journal rank" the-one-percent.qedscience.com 1/n
Souvenir from the Cell Biology of the Neuron GRC in beautiful Tuscany. A great community, looking forward to meet everyone again in two years with @barrlab.bsky.social and @roylab-ucsd.bsky.social at the helm!
