Stephan Uphoff

@uphoff.bsky.social

Professor of Physical Microbiology at Oxford University. Investigating bacterial DNA Repair and Mutagenesis. Imaging single molecules and single cells.

academic.oup.com/nar/article/... Collaboration with Y. Yamaichi. Killing donor bacteria in conjugation mixes using water enables transcriptomic profiling of early plasmid genes ! Superb tool for studying zygotic induction of these early genes, which include anti-SOS and anti-RM factors. #microsky

Selective elimination of donor bacteria enables global profiling of plasmid gene expression at early stages of conjugation

Abstract. Conjugative plasmids are a major driving force for the dissemination of antimicrobial resistance. During conjugation, plasmid DNA is transferred

academic.oup.com